Genetically engineered kidneys.

A S Woolf; L G Fine

doi:10.1007/bf00852565

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PubMed · 8251332

Genetically engineered kidneys.

A S Woolf·L G Fine

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Abstract

We review the available methods of creating genetically engineered kidneys. These include transgenic technology to introduce novel genes or delete existing genes and methods of gene transfer into the post-natal or adult kidney. The use of such technology has provided insights into renal development and growth and created new animal models of human diseases. Although some of these techniques are of potential use for introducing therapeutically useful gene products into the diseased kidney, many problems remain to be solved before this aim is attained.

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Animals Chromosome Deletion Disease Models, Animal Gene Expression Gene Transfer Techniques Genetic Engineering Kidney Kidney Diseases Mice Mice, Transgenic Journal Article Research Support, Non-U.S. Gov't Research Support, U.S. Gov't, P.H.S.Review

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A S Woolf, L G Fine. 1993. Genetically engineered kidneys.. https://doi.org/10.1007/bf00852565

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