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Capillary permeability in cutaneous tissue.

W P Paaske
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Abstract

Capillary permeability in cutaneous tissue was determined by the single injection, external counting method. A rabbit abdominal skin preparation was developed. After local vasodilatation, 5 mul (400 muCi) 51Cr-EDTA was administered intraarterially by a special bolus injection technique, and the response curve was recorded by external registration. The capillary diffusion capacity (the permeability-surface area product) for 51Cr-EDTA amounted to 3.7 ml/100 g-min at a capillary extraction of 0.59 and a plasma flow of 4.8 ml/100 g-min. The permeability coefficient for 51Cr-EDTA in cutaneous tissue was calculated to 0.9-10-5 cm/s assuming a capillary surface area of 70 cm2/g.

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AnimalsCapillary PermeabilityEdetic AcidFemaleMethodsRabbitsRegional Blood FlowSkinJournal Article

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BibTeXRIS

W P Paaske. 1976. Capillary permeability in cutaneous tissue.. https://doi.org/10.1111/j.1748-1716.1976.tb10341.x

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