Accommodative and pupillary responses to sinusoidal target depth movement.

Abstract

We evaluated the accommodative and pupillary responses to sinusoidal target depth movement in 10 normal subjects and one patient by analysing frequency responses and associated Bode plots. The phase of the pupillary response significantly lagged behind that of accommodative response, which suggests that they are controlled by separate central nervous systems. We measured the baseline shift of each response trace using a regression line and found that they were larger at higher stimulation frequencies. A patient with severe asthenopia showed a considerable baseline shift in accommodative response. These analyses may be useful for the quantitative assessment of dynamic accommodation and pupillary response.