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Reduced total complement haemolytic activity in schizophrenic patients.

B Spivak·M Radwan·J Brandon·Y Baruch·M Stawski·S Tyano·A Weizman
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Abstract

Serum concentrations of the third and fourth components of the complement system and total complement haemolytic activity were measured in 167 psychiatric patients. Total complement haemolytic activity was decreased in chronic schizophrenic patients as compared to healthy controls and bipolar patients. The relatively diminished total haemolytic activity was not attributable to drug treatment. It is not clear if the reduced total haemolytic activity is an epiphenomenon or related to the involvement of an autoimmune process in the pathophysiology of schizophrenia.

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Autoimmune DiseasesBipolar DisorderChronic DiseaseComplement ActivationComplement C3Complement C4Depressive DisorderFemaleHaloperidolHemolysisHumansLithium CarbonateMaleMiddle AgedSchizophreniaSchizophrenic PsychologyJournal Article

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B Spivak, M Radwan, J Brandon, Y Baruch, M Stawski, S Tyano, A Weizman. 1993. Reduced total complement haemolytic activity in schizophrenic patients.. https://doi.org/10.1017/s0033291700028397

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