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PubMed · 8336813

[A case of diffuse idiopathic skeletal hyperostosis (DISH) causing dysphagia].

T Kubokura·N Sanno·J Hotta·H Ozawa
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Abstract

A case of diffuse idiopathic skeletal hyperostosis causing dysphasia was reported. A 62 year-old man was admitted to our hospital complaining of nuchal pain and dysphagia. Roentgenograms of the cervical spine demonstrated a "flowing" ossification anterior to three contiguous vertebral bodies, C 4-6. Esophagraphic examination demonstrated esophageal compression caused by the enormous ossification. Roentgenograms of the thoracic and lumbar spine revealed an anterior bony bridge and prediscal ossicles at multiple levels of the vertebral column. These radiographic features were characteristic of DISH. The authors discussed the symptomatology, differential diagnosis and treatment of DISH mainly involving the cervical region, and emphasized the importance of being able to recognize this unfamiliar disorder in the neurosurgical clinic.

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Cervical VertebraeDeglutition DisordersDiagnosis, DifferentialHumansHyperostosis, Diffuse Idiopathic SkeletalMaleMiddle AgedRadiographyCase ReportsJournal Article

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T Kubokura, N Sanno, J Hotta, H Ozawa. 1993. [A case of diffuse idiopathic skeletal hyperostosis (DISH) causing dysphagia].. https://pubmed.ncbi.nlm.nih.gov/8336813/

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PubMed2007

Surgical treatment of cervical kyphosis in Larsen syndrome: report of 3 cases and review of the literature.

STUDY DESIGN: A retrospective case series. OBJECTIVE: To review the surgical results for midcervical kyphosis in 3 cases with Larsen syndrome, and to discuss the choice of surgical treatments. SUMMARY OF BACKGROUND DATA: Cervical kyphosis is the most hazardous and serious manifestation of Larsen syndrome due to the risk of life-threatening paralysis, and thus usually requires surgical treatment. However, little information has been reported concerning surgical treatments for this challenging condition. METHODS: Three patients with Larsen syndrome were surgically treated for midcervical kyphosis at our institution. RESULTS: An infant with mild cervical kyphosis was successfully treated with posterior arthrodesis using a halo immobilization, and anterior vertebral growth with a mature posterior fusion mass resulted in spontaneous correction of the kyphosis. In the remaining 2 infants with myelopathic symptoms due to severe and structural kyphosis, anterior decompression and fusion via a lateral approach followed by posterior fusion with segmental spinal instrumentation and halo immobilization resulted in improved neurologic symptoms and solid fusion. CONCLUSIONS: Posterior spinal fusion is only indicated for patients with mild and flexible cervical kyphosis, and anterior decompression and circumferential arthrodesis is required for patients with severe kyphotic deformity, who usually develop myelopathic symptoms. Anterior surgery for such a small patient with severe kyphosis involves much higher risk of spinal cord injury during decompression maneuvers and difficulty in stabilization of the reconstructed cervical spine. Therefore, all patients with Larsen syndrome should be screened with radiographs at the first visit to detect cervical kyphosis early so that posterior alone fusion is possible.

Cervical Vertebrae↗