Virulence-associated plasmids in Rhodococcus equi.

S Takai; Y Watanabe; T Ikeda; T Ozawa; S Matsukura; Y Tamada; S Tsubaki; T Sekizaki

doi:10.1128/jcm.31.7.1726-1729.1993

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PubMed · 8349748

Virulence-associated plasmids in Rhodococcus equi.

S Takai·Y Watanabe·T Ikeda·T Ozawa·S Matsukura·Y Tamada·S Tsubaki·T Sekizaki

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Abstract

Twenty-three strains of Rhodococcus equi from independent clinical cases were analyzed for the presence of virulence plasmid DNA. Of the clinical isolates, 19 contained an 85-kb plasmid and the remaining 4 contained a 90-kb plasmid. All of the isolates expressed 15- to 17-kDa antigens and were virulent in mice. Restriction enzyme and Southern blot analyses showed large regions of DNA homology between the 85- and 90-kb virulence plasmids. It was concluded tentatively that there are at least two virulence plasmids in R. equi and that they have a common origin.

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S Takai, Y Watanabe, T Ikeda, T Ozawa, S Matsukura, Y Tamada, S Tsubaki, T Sekizaki. 1993. Virulence-associated plasmids in Rhodococcus equi.. https://doi.org/10.1128/jcm.31.7.1726-1729.1993

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