Two developmentally regulated mRNAs encoding actin-binding proteins in Physarum polycephalum.

B St-Pierre; C Couture; A Laroche; D Pallotta

doi:10.1016/0167-4781(93)90254-b

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Two developmentally regulated mRNAs encoding actin-binding proteins in Physarum polycephalum.

B St-Pierre·C Couture·A Laroche·D Pallotta

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Abstract

A cDNA library from amoebae of Physarum polycephalum was screened by differential hybridization. Two clones contained inserts for mRNAs present in amoebae and absent in plasmodia. The LAV3-4 cDNA encodes a 402 aa protein (ABP-46) that shows sequence similarity to the actin binding site in the N-terminal region of the alpha-actinin family. The LAV3-5 cDNA is 76% identical to the Dictyostelium actin bundling protein, which cross-links and stabilizes actin filaments in amoebal filopodia.

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Actinin Amino Acid Sequence Animals Base Sequence Dictyostelium Fungal Proteins Molecular Sequence Data Physarum polycephalum RNA, Messenger Comparative Study Journal Article Research Support, Non-U.S. Gov't

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B St-Pierre, C Couture, A Laroche, D Pallotta. 1993-04-29. Two developmentally regulated mRNAs encoding actin-binding proteins in Physarum polycephalum.. https://doi.org/10.1016/0167-4781(93)90254-b

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