Intermodality, retrospective image registration in the thorax.

J N Yu; F H Fahey; H D Gage; C G Eades; B A Harkness; C A Pelizzari; J W Keyes

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PubMed · 8523127

Intermodality, retrospective image registration in the thorax.

J N Yu·F H Fahey·H D Gage·C G Eades·B A Harkness·C A Pelizzari·J W Keyes

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Abstract

UNLABELLED: The purpose of this study was to develop an accurate, retrospectively applicable procedure for registering thoracic studies from different modalities in a short amount of time and with minimal operator intervention. METHODS: CT and PET studies were acquired from six patients. The pleural surfaces in both image sets were determined by segmenting based on 50% of the maximum soft-tissue value in the study. These surfaces were converted into three-dimensional volumes and used to register the CT and PET studies in three dimensions using a sum of least squares fitting approach. The registered PET study was then displayed in a hot metal scale overlayed on top of the gray scale CT study. The accuracy of the fit was evaluated through a phantom study and preliminary clinical evaluation. RESULTS: A phantom study was performed to determine the limits of this technique. The accuracy was determined to be less than 2.3 mm in the x and y direction and 3 mm in the z direction. Preliminary clinical evaluation was also performed with encouraging results. CONCLUSION: This technique accurately registers PET and CT images of the thorax, retrospectively, without the need for external fiducial markers or other a priori action.

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J N Yu, F H Fahey, H D Gage, C G Eades, B A Harkness, C A Pelizzari, J W Keyes. 1995. Intermodality, retrospective image registration in the thorax.. https://pubmed.ncbi.nlm.nih.gov/8523127/

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