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PubMed · 8599299

A simple quality control protocol for haemoximetry using standard p50.

J Morgan·A Clague·J Rayfield·Z Endre
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Abstract

We have designed a quality control tool for haemoximetry using the principle that standard p50, calculated from blood gas and haemoximetry measurements using the Siggaard-Andersen algorithm, remains unchanged when a specimen of venous blood is oxygenated progressively to 97% saturation of haemoglobin. If the haemoximeter is inaccurate, progressively larger deviations of standard p50 from the constant value occur above 80% saturation. Deviations too small to be detected by analysis of quality control materials comprised of non-haemoglobin dyes and yet sufficient to cause significant errors in derived extractivity parameters can be detected by this method. The suggested protocol is easy to perform, and is recommended as a quality control tool for blood gas analyser/haemoximeters used to determine arterial extractivity parameters.

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AlgorithmsBiasBlood Gas AnalysisCalibrationColoring AgentsHemoglobinometryHemoglobinsHumansHydrogen-Ion ConcentrationOxygenQuality ControlSpectrophotometryJournal Article

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J Morgan, A Clague, J Rayfield, Z Endre. 1995. A simple quality control protocol for haemoximetry using standard p50.. https://pubmed.ncbi.nlm.nih.gov/8599299/

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