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PubMed · 865291

A cytogeneticist's microscope.

D K Green·R Bayley·D Rutovitz
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Abstract

It is demonstrated that there are a number of advantages in using a mechanised microscope for scoring a large number of metaphase cells from human blood lymphocyte preparations. Following the development of an automatic metaphase spread finding machine based upon a large motorised microscope and a synchronous closed circuit television camera and flashing light source, a much smaller machine which is more appropriate to the cytogenetics laboratory, but with a similar metaphase finding performance has been constructed. The new machine which consists of a Cambridge Instruments 1 micron stepping microscope stage, a linear diode array scanner and a computer is described in detail. Metaphase finding performance figures for various orcein stained human blood lymphocyte preparations are given.

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CytogeneticsHumansKaryotypingLymphocytesMicroscopyMitosisJournal Article

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D K Green, R Bayley, D Rutovitz. 1977. A cytogeneticist's microscope.. https://pubmed.ncbi.nlm.nih.gov/865291/

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