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PubMed · 8825571

Canine osteosarcoma: amputation and chemoimmunotherapy.

E G MacEwen·I D Kurzman
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Abstract

Canine osteosarcoma is a highly metastatic cancer commonly seen in large breed dogs. At the time of diagnosis, approximately 90% to 95% of the dogs have established micrometastases. Dogs undergoing amputation alone have a median survival time of 3 to 4 months. Amputation followed by cisplatin chemotherapy increases median survival times to 9 to 11 months. When dogs are treated with amputation and cisplatin, followed by immunotherapy (with liposome-encapsulated muramyl tripeptide phosphatidylethanolamine), median survival times increase to 14.4 months, the longest reported median survival time for dogs with osteosarcoma treated by amputation and any form of adjuvant therapy.

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Acetylmuramyl-Alanyl-IsoglutamineAmputation, SurgicalAnimalsAntineoplastic AgentsBone NeoplasmsCisplatinCombined Modality TherapyDog DiseasesDogsDrug Therapy, CombinationImmunotherapyOsteosarcomaPhosphatidylethanolaminesJournal ArticleResearch Support, Non-U.S. Gov'tReview

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BibTeXRIS

E G MacEwen, I D Kurzman. 1996. Canine osteosarcoma: amputation and chemoimmunotherapy.. https://doi.org/10.1016/s0195-5616(96)50011-2

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Acetylmuramyl-Alanyl-Isoglutamine↗
PubMed2007

NOD protein expression and function in first trimester trophoblast cells.

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Acetylmuramyl-Alanyl-Isoglutamine↗