[Haptoglobin and ceruloplasmin in systemic scleroderma].

Z I Volkova; A S Kaĭnova; R M Balabanova

PubMed · 888393

[Haptoglobin and ceruloplasmin in systemic scleroderma].

Abstract

Content of haptoglobin and ceruloplasmin was estimated in blood serum of 23 patients with sclerodermia systematica. A statistically distinct decrease in ceruloplasmin concentration was observed in blood of the patients, whereas content of haptoglobin was markedly increased; this phenomenon reflects a level of the pathological process activity. The proteins are synthesized in various zones of liver lobes: haptoglobin--in the central zone, ceruloplasmin - in the peripheral one. Decrease in content of ceruloplasmin in blood of patients with sclerodermia systematica was due to impairment of hepatocytes, localized in peripheral parts of liver lobes.

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Animals Carbon Tetrachloride Poisoning Ceruloplasmin Chemical and Drug Induced Liver Injury Haptoglobins Humans Rabbits Scleroderma, Systemic Journal Article

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Z I Volkova, A S Kaĭnova, R M Balabanova. [Haptoglobin and ceruloplasmin in systemic scleroderma].. https://pubmed.ncbi.nlm.nih.gov/888393/

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