Red blood cell adhesion on a solid/liquid interface.

P Lavalle; J F Stoltz; B Senger; J C Voegel; P Schaaf

doi:10.1073/pnas.93.26.15136

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Red blood cell adhesion on a solid/liquid interface.

P Lavalle·J F Stoltz·B Senger·J C Voegel·P Schaaf

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Abstract

Red blood cells (RBCs), previously fixed with glutaraldehyde, adhere to glass slides coated with fibrinogen. The RBC deposition process on the horizontal glass surface is investigated by analyzing the relative surface covered by the RBCs, as well as the variance of this surface coverage, as a function of the concentration of particles. This study is performed by optical microscopy and image analysis. A model, derived from the classical random sequential adsorption model, has been developed to account for the experimental results. This model highlights the strong influence of the hydrodynamic interactions during the deposition process.

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Adsorption Cell Adhesion Erythrocytes Fibrinogen Glass Glutaral Humans Mathematics Microscopy, Electron, Scanning Models, Biological Surface Properties Journal Article Research Support, Non-U.S. Gov't

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P Lavalle, J F Stoltz, B Senger, J C Voegel, P Schaaf. 1996-12-24. Red blood cell adhesion on a solid/liquid interface.. https://doi.org/10.1073/pnas.93.26.15136

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