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Acute generalized exanthematous pustulosis.

C Beylot·M S Doutre·M Beylot-Barry
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Abstract

Acute generalized exanthematous pustulosis (AGEP) is now a well-known clinical entity, characterized by acute onset with associated fever, and numerous non-follicular pin-head sterile pustules on erythematous background. The biopsy evidences subcorneal pustules resembling those of pustular psoriasis. However, polymorphic aspects such as pseudo-erythema multiforme purpuric lesions, and edema are often associated, and with the rapid self-healing course of this impressive pustulosis, allow the differential diagnosis with pustular psoriasis. Most cases of AGEP are drug induced, particularly by antibiotics and mainly beta-lactams. However, a number of other drugs, of which the list is increasing, may be responsible. Few cases are related to other causative factors such as viral infections or ultraviolet radiation.

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Diagnosis, DifferentialDrug EruptionsHumansHypersensitivity, ImmediatePrognosisSkin Diseases, PapulosquamousJournal ArticleReview

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BibTeXRIS

C Beylot, M S Doutre, M Beylot-Barry. 1996. Acute generalized exanthematous pustulosis.. https://doi.org/10.1016/s1085-5629(96)80037-x

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