Renal K+ channels: structure and function.

W Wang; S C Hebert; G Giebisch

doi:10.1146/annurev.physiol.59.1.413

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Renal K+ channels: structure and function.

W Wang·S C Hebert·G Giebisch

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Abstract

The activity of potassium (K+) channels is intimately linked to several important transport functions in renal tubules. We review recent progress concerning the properties, site along the nephron, and physiological regulation of native K+ channels, and compare their characteristics with those of recently cloned K+ channels. We do not fully cover work on K+ channels in amphibian tubules, cell cultures, and single tubule cells and do not review K+ channels in mesangial cells.

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Animals Cell Membrane Kidney Kidney Tubules, Collecting Kidney Tubules, Proximal Loop of Henle Molecular Conformation Potassium Channels Structure-Activity Relationship Journal Article Research Support, U.S. Gov't, P.H.S.Review

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W Wang, S C Hebert, G Giebisch. 1997. Renal K+ channels: structure and function.. https://doi.org/10.1146/annurev.physiol.59.1.413

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