Hydroxyzine therapy for interstitial cystitis.

T C Theoharides; G R Sant

doi:10.1016/s0090-4295(97)00182-9

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Hydroxyzine therapy for interstitial cystitis.

T C Theoharides·G R Sant

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Abstract

OBJECTIVES: To determine the usefulness of oral hydroxyzine for the treatment of symptomatic interstitial cystitis. METHODS: This study was an open-label, nonconsecutive case series of patients treated by their local physicians, in consultation with the authors. A case-report form using visual analog scales was used to assess outcomes. RESULTS: Out of 140 patients, 90 (65%) returned the case-report forms. A 40% reduction in symptom scores was reported. This rose to 55% in patients with a history of allergies. CONCLUSIONS: Hydroxyzine is a useful drug for the symptomatic treatment of IC, especially in patients with documented allergies and/or evidence of bladder mast cell activation.

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T C Theoharides, G R Sant. 1997. Hydroxyzine therapy for interstitial cystitis.. https://doi.org/10.1016/s0090-4295(97)00182-9

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