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PubMed · 9188546

Intrinsic optical changes in neuronal tissue. Basic mechanisms.

D W Hochman
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Abstract

Associated with changes in the level of physiological activity in neuronal tissue are changes in the intrinsic optical properties of the tissue. As a consequence, it is possible to optically monitor neuronal activity without the use of dyes or other contrast-enhancing agents. Such optical techniques have been applied in the laboratory for more than 50 years. Recent developments in near-infrared spectroscopy and intraoperative optical imaging have suggested a number of clinically important applications of this technology. This article provides an overview of what is known about the physiological correlates and underlying mechanisms associated with activity-evoked optical changes in neuronal tissue.

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BrainFluorescenceHumansNerve TissueNeuronsOptics and PhotonicsPhysical PhenomenaPhysicsScattering, RadiationJournal ArticleReview

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D W Hochman. 1997. Intrinsic optical changes in neuronal tissue. Basic mechanisms.. https://pubmed.ncbi.nlm.nih.gov/9188546/

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