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PubMed · 9230454

A computer program for constructing multivariate reference models.

M Hekking·J Lindemans·E S Gelsema
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Abstract

From a statistical point of view the simultaneous interpretation of multiple variables should be performed with a multivariate reference model rather than with multiple univariate reference intervals. A computer program for constructing and testing multivariate reference models is described. The use of the computer program is illustrated with a data set of total serum calcium concentrations and serum albumin concentrations from 222 2nd year medical students. Using a single univariate reference interval for total serum calcium, 17 students were classified as having an abnormal calcemic status while using a bivariate reference model for total serum calcium and serum albumin, 13 of these 17 students had in fact normal total serum calcium concentrations, taking into account their serum albumin concentrations.

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BiometryCalciumHumansModels, BiologicalModels, StatisticalMultivariate AnalysisReference ValuesSerum AlbuminSoftwareJournal Article

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BibTeXRIS

M Hekking, J Lindemans, E S Gelsema. 1997. A computer program for constructing multivariate reference models.. https://doi.org/10.1016/s0169-2607(97)00018-7

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