Nucleotide sequence of equine MxA cDNA.

P M Chesters; M Steele; A Purewal; N Edington

doi:10.3109/10425179709034043

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Nucleotide sequence of equine MxA cDNA.

P M Chesters·M Steele·A Purewal·N Edington

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Abstract

A 2.6 kb cDNA species has been isolated from a cDNA library prepared from interferon-alpha stimulated equine peripheral blood leucocytes and the nucleotide sequence determined. The cDNA has a single open reading frame potentially encoding a 660 amino acid polypeptide showing a high degree of homology with known mammalian Mx proteins, including the possession of three consensus GTP-binding motifs. The protein has a calculated pI = 6.1 and in accordance with proposed nomenclature we have designated it equine MxA.

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Amino Acid Sequence Animals Base Sequence GTP-Binding Proteins Horses Molecular Sequence Data Myxovirus Resistance Proteins Protein Biosynthesis Proteins Sequence Analysis, DNA Journal Article Research Support, Non-U.S. Gov't

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P M Chesters, M Steele, A Purewal, N Edington. 1997. Nucleotide sequence of equine MxA cDNA.. https://doi.org/10.3109/10425179709034043

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