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PubMed · 951886

Endothelial-cell development: pressure-flow phenomena.

V F Burpee·W V Sharp·D V Hillegass·R J Arconti
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Abstract

Scanning electron micrographs showed directional orientation and cytoplasmic changes in the seeded cells after 21 days of perfusion. From this evidence it is theorized that human fibroblasts, exposed to physiological pressures and flows, exhibit morphological characteristics similar to arterial endothelial cells. Conceivably, cells other than fibroblasts (i.e., multipotential cells) would show the same response to these pressure and flow conditions.

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Blood CirculationCardiovascular Physiological PhenomenaEndotheliumFibroblastsMicroscopy, Electron, ScanningModels, BiologicalPressureRegenerationJournal Article

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V F Burpee, W V Sharp, D V Hillegass, R J Arconti. 1976. Endothelial-cell development: pressure-flow phenomena.. https://pubmed.ncbi.nlm.nih.gov/951886/

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Understanding the pathophysiology of intra-uterine growth retardation: the role of the 'lower limb reflex' in redistribution of blood flow.

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