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Schizophrenia as a consequence of brain evolution.

P L Randall
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Abstract

Connectionist integration of central nervous system function may have proceeded by a process of biological trial and error throughout brain evolution. As existing structures enlarged, and as new elements of brain function were added, misconnectionist variants could arise. This might account for a number of developmental syndromes in the human brain including schizophrenia. Ultimately, these would derive from aspects of hominid brain evolution and its vertebrate ancestry.

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AnimalsBiological EvolutionCerebral CortexCognitionFemaleHominidaeHumansLanguageMaleNeural PathwaysSchizophreniaSex CharacteristicsVertebratesJournal Article

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P L Randall. 1998-03-10. Schizophrenia as a consequence of brain evolution.. https://doi.org/10.1016/s0920-9964(97)00143-6

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