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PubMed · 9645916

Mathematical model for the blood coagulation prothrombin time test.

M A Khanin·D V Rakov·A E Kogan
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Abstract

A mathematical model for the prothrombin time test is proposed. The time course of clotting factor activation during coagulation was calculated, and the sensitivity of the test to a decrease in the concentrations of coagulation proteins or their activities was studied. The model predicts that only severe coagulation disorders connected with a more than five-fold decrease in the concentrations or activities of the blood coagulation factors can be revealed by the test.

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Blood Coagulation FactorsBlood Coagulation TestsHumansModels, BiologicalPartial Thromboplastin TimeSensitivity and SpecificityJournal Article

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BibTeXRIS

M A Khanin, D V Rakov, A E Kogan. 1998-03-01. Mathematical model for the blood coagulation prothrombin time test.. https://doi.org/10.1016/s0049-3848(97)00288-0

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