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PubMed · 9653478

The evaluation of ciliary function: electron versus light microscopy.

S B Kupferberg·J P Bent·E S Porubsky
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Abstract

Diagnosing Primary Ciliary Dyskinesia can often be difficult. Physical findings suggest the disease, but definitive diagnosis should be made with a ciliary biopsy. Twenty biopsies were obtained from 16 patients and all underwent both light and electron microscopic examination. In 8/20 (40%) there was a discrepancy between the different imaging techniques. Therefore, light microscopy should be used to assess adequacy of biopsy and motion of the cilia along with electron microscopy to examine ultrastructure.

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BiopsyBronchitisChronic DiseaseCiliaCiliary Motility DisordersDyneinsEvaluation Studies as TopicHumansMicroscopyMicroscopy, ElectronMicrotubulesMovementMucous MembraneNasal MucosaOtitis MediaParanasal SinusesPneumoniaRetrospective StudiesSinusitisTracheaJournal Article

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S B Kupferberg, J P Bent, E S Porubsky. The evaluation of ciliary function: electron versus light microscopy.. https://doi.org/10.2500/105065898781390172

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