Standardized echography, pattern electroretinography and visual-evoked potential and automated perimetry in the early diagnosis of Graves' neuropathy.

F Genovesi-Ebert; E Di Bartolo; A Lepri; V Poggi; A Romani; M Nardi

doi:10.1159/000055442

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Standardized echography, pattern electroretinography and visual-evoked potential and automated perimetry in the early diagnosis of Graves' neuropathy.

F Genovesi-Ebert·E Di Bartolo·A Lepri·V Poggi·A Romani·M Nardi

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Abstract

Twenty-four patients (47 eyes) affected by Graves' disease were enrolled to evaluate the role of standardized echography, pattern electroretinogram (P-ERG), visual evoked potentials (P-VEPs) and automated perimetry in the early diagnosis of the compressive optic neuropathy (CON). The P-ERG amplitude reduction was the most sensitive parameter to demonstrate an early impairment of the optic nerve (ON) function. We found a significant negative correlation between the ON diameter and the P-ERG amplitude. VEPs responses were also altered, but their ability in detecting an early ON damage was less sensitive and specific than P-ERG. The visual field damage was often aspecific and delayed with respect to electrophysiological alterations.

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Electroretinography Evoked Potentials, Visual Graves Disease Humans Middle Aged Optic Neuropathy, Ischemic Prognosis Sensitivity and Specificity Ultrasonography Visual Acuity Visual Field Tests Visual Fields Comparative Study Journal Article

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F Genovesi-Ebert, E Di Bartolo, A Lepri, V Poggi, A Romani, M Nardi. 1998. Standardized echography, pattern electroretinography and visual-evoked potential and automated perimetry in the early diagnosis of Graves' neuropathy.. https://doi.org/10.1159/000055442

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