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Computational methods for exon detection.

J M Claverie
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Abstract

Computer methods for the complete and accurate detection of genes in vertebrate genomic sequences are still a long way to perfection. The intermediate task of identifying the coding moiety of genes (coding exons) is now reasonably well achieved using a combination of methods. After reviewing the intrinsic difficulties in interpreting vertebrate genomic sequences, this article presents the state-of-the-art, with an emphasis on similarity search methods and the resources available through Internet.

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AnimalsBase SequenceComputing MethodologiesConserved SequenceDatabases, FactualEuropeExonsGenesHumansInternetJapanMolecular Sequence DataSequence Homology, Amino AcidSequence Homology, Nucleic AcidUnited StatesUser-Computer InterfaceVertebratesJournal ArticleResearch Support, Non-U.S. Gov'tReview

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J M Claverie. 1998. Computational methods for exon detection.. https://doi.org/10.1007/bf02745861

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