[Normal antibodies and immunologic reactivity].

M I Levi; T S Selezneva; M M Livshits; N N Sakaian

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PubMed · 986741

[Normal antibodies and immunologic reactivity].

M I Levi·T S Selezneva·M M Livshits·N N Sakaian

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Abstract

Antibodies to the capsular antigen of plague causative agent were found in the serum of many nonimmunized mice of 6 strains, but none were found in mice of the DBA/2 strain. After the administration of the capsular antigen to mice of different strains cells forming the antibodies to the antigen administered were revealed in a quantitative correlation with the natural antibody level. An association was revealed between the level of natural antibodies and the number of antibody-forming cells in the spleen of nonimmunized mice; it could be described by an equation almost all of whose members represented constant values with a definite quantitative characteristics. To check the suggested equation the concentration of immunoglobulins in the blood of mice was compared with the number of plasma cells in the spleen; a satisfactory correlation was revealed between them.

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Animals Antibodies, Bacterial Antibody-Producing Cells Antigens, Bacterial Cell Count Mice Mice, Inbred Strains Plasma Cells Spleen Yersinia pestis Comparative Study Journal Article

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M I Levi, T S Selezneva, M M Livshits, N N Sakaian. 1976. [Normal antibodies and immunologic reactivity].. https://pubmed.ncbi.nlm.nih.gov/986741/

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