Bilateral Wilms' tumor.

C M Kullendorff; T Wiebe

doi:10.1007/s003830050510

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PubMed · 9914355

Bilateral Wilms' tumor.

C M Kullendorff·T Wiebe

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Abstract

During a 16-year period, 49 children were treated for Wilms' tumor (WT); 7 were bilateral, 5 synchronous and 2 metachronous. The age at primary diagnosis was 6 months to 5 years (mean 2.4 years). All but 1 child received preoperative chemotherapy with tumor reduction. Unilateral nephrectomy was performed in 2 metachronous cases. In 3 synchronous WTs, the tumor was enucleated in 5 kidneys and a heminephrectomy was performed in 1 kidney with a double pelvis. Two children were not operated upon. At relapse in the contralateral kidney the tumor was enucleated. Three patients died of WT, 1 is alive with disease, and 3 are without evidence of disease. Renal salvage procedures were technically feasible without complications and are advocated to preserve renal function.

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Antineoplastic Agents Child, Preschool Combined Modality Therapy Female Humans Infant Kidney Neoplasms Male Neoplasms, Multiple Primary Neoplasms, Second Primary Nephrectomy Treatment Outcome Wilms Tumor Journal Article Research Support, Non-U.S. Gov't

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C M Kullendorff, T Wiebe. 1999. Bilateral Wilms' tumor.. https://doi.org/10.1007/s003830050510

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