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Seven ways to increase power without increasing N.

Many readers of this monograph may wonder why a chapter on statistical power was included. After all, by now the issue of statistical power is in many respects mundane. Everyone knows that statistical power is a central research consideration, and certainly most National Institute on Drug Abuse grantees or prospective grantees understand the importance of including a power analysis in research proposals. However, there is ample evidence that, in practice, prevention researchers are not paying sufficient attention to statistical power. If they were, the findings observed by Hansen (1992) in a recent review of the prevention literature would not have emerged. Hansen (1992) examined statistical power based on 46 cohorts followed longitudinally, using nonparametric assumptions given the subjects' age at posttest and the numbers of subjects. Results of this analysis indicated that, in order for a study to attain 80-percent power for detecting differences between treatment and control groups, the difference between groups at posttest would need to be at least 8 percent (in the best studies) and as much as 16 percent (in the weakest studies). In order for a study to attain 80-percent power for detecting group differences in pre-post change, 22 of the 46 cohorts would have needed relative pre-post reductions of greater than 100 percent. Thirty-three of the 46 cohorts had less than 50-percent power to detect a 50-percent relative reduction in substance use. These results are consistent with other review findings (e.g., Lipsey 1990) that have shown a similar lack of power in a broad range of research topics. Thus, it seems that, although researchers are aware of the importance of statistical power (particularly of the necessity for calculating it when proposing research), they somehow are failing to end up with adequate power in their completed studies. This chapter argues that the failure of many prevention studies to maintain adequate statistical power is due to an overemphasis on sample size (N) as the only, or even the best, way to increase statistical power. It is easy to see how this overemphasis has come about. Sample size is easy to manipulate, has the advantage of being related to power in a straight-forward way, and usually is under the direct control of the researcher, except for limitations imposed by finances or subject availability. Another option for increasing power is to increase the alpha used for hypothesis-testing but, as very few researchers seriously consider significance levels much larger than the traditional .05, this strategy seldom is used. Of course, sample size is important, and the authors of this chapter are not recommending that researchers cease choosing sample sizes carefully. Rather, they argue that researchers should not confine themselves to increasing N to enhance power. It is important to take additional measures to maintain and improve power over and above making sure the initial sample size is sufficient. The authors recommend two general strategies. One strategy involves attempting to maintain the effective initial sample size so that power is not lost needlessly. The other strategy is to take measures to maximize the third factor that determines statistical power: effect size.

Data Interpretation, Statistical↗

A direct method to measure the power of the central cornea after myopic laser in situ keratomileusis.

OBJECTIVE: To measure the corneal power after myopic laser in situ keratomileusis (LASIK). METHODS: Six central areas in 6 corneal power maps were studied using the Orbscan II statistical analysis device in 26 eyes that underwent myopic LASIK. Refractive and corneal power changes were compared. Factors related to wrong corneal power measurement were evaluated. MAIN OUTCOME MEASURES: Cycloplegic refraction, refractive change at the corneal plane, and Orbscan II corneal power maps. RESULTS: Preoperatively, only posterior-mean power (P<<.001) and anterior-posterior power ratio (P<<.001) varied according to the size of the analyzed area. Postoperatively, total-optical (P =.03), keratometric-mean (P =.04), total-mean (P<.001), anterior-mean (P =.03), and posterior-mean (P<<.001) powers; and anterior-posterior power ratio (P<<.001) varied according to the area. Postoperatively, the difference between keratometric-mean and total-mean powers became larger (P<.001), and the anterior-posterior power ratio was reduced (P<<.001). A posterior-mean power change occurred (P =.04). Refractive change after myopic LASIK was best estimated by 2-mm total-mean power (mean +/- SD difference, 0.07 +/- 0.62 diopters [D]; P =.55) and 4-mm total-optical power (mean +/- SD difference, -0.08 +/- 0.53 D; P =.37). CONCLUSIONS: Total corneal power is more positive and refractive change is underestimated when deduced from the anterior surface radius and keratometric refractive index. The anterior-posterior power ratio is not a fixed value. The best area to estimate the refractive change depends on the method used to obtain the power in diopters. Refractive change tended to be underestimated in larger areas and higher preoperative myopia. Orbscan II total-mean and total-optical power maps accurately assess the corneal power after myopic LASIK independent of preoperative data or correcting factors, and should improve intraocular lens calculation.

Adult↗

Determining corneal power using Orbscan II videokeratography for intraocular lens calculation after excimer laser surgery for myopia.

PURPOSE: To assess the accuracy of Orbscan II slit-scanning videokeratography for intraocular lens (IOL) calculation in eyes with previous photorefractive surgery for myopia. SETTING: Private practice, St. Louis, Missouri, USA. METHODS: Corneal power (K) was measured by manual keratometry, Placido-based videokeratography (Atlas), slit-scanning videokeratography (Orbscan II), and contact lens overrefraction in 21 post-photoablation eyes having cataract surgery. Postoperative data collected after phacoemulsification were used to back-calculate corneal power (BCK). The BCK values were statistically compared at 3.0 to 6.0 mm central Orbscan II curvature and power measurements, including total axial power, total tangential power, total mean power, and total optical power. Similar comparisons were made to Atlas curvature at the 0.0 to 10.0 mm zones. RESULTS: The mean corneal power after refractive surgery based on BCK values using the Holladay 2 formula (BCK H2) was 39.35 diopters (D) +/- 2.58 (SD). The mean manual value (40.52 +/- 1.95 D) and Atlas-based values were statistically higher than BCK H2 values (P<.001). The mean corneal power calculated from historical data was 39.33 +/- 2.70 D (P = .83 to BCK H2; n = 19) and from contact lens overrefraction, 41.38 +/- 3.11 D (P = .19; n = 5). Orbscan II parameters (n = 21) of the total mean power (3.0 mm, 39.10 +/- 2.63 D), total tangential power (3.0 mm, 39.11 +/- 2.60), total axial power (5.0 mm, 39.19 +/- 2.55 D), and total optical power (3.0 mm, 39.08 +/- 2.78 D; 4.0 mm, 39.39 +/- 2.76 D) were statistically similar to both the historical and BCK H2 values (P>.11). If used prospectively, 80.9% of eyes would have been within +/-0.50 D of the targeted refraction using a 4.0 mm total optical power, 76.2% using a 5.0 mm total axial power, and 42.1% using the historical method. CONCLUSION: The Orbscan II 5.0 mm total axial power and 4.0 mm total optical power can be used to more accurately predict true corneal power than the history-based method and may be particularly useful when pre-LASIK data are unavailable.

Cataract↗

[Pitfalls of IOL power prediction after photorefractive keratectomy for high myopia -- case report, practical recommendations and literature review].

BACKGROUND AND PURPOSE: Published experience with eyes after keratorefractive correction of myopia indicates that insertion of the average keratometric readings into standard IOL power predictive formulas will frequently result in substantial undercorrection and postoperative hyperopic refraction or anisometropia after cataract surgery depending on the amount of myopia corrected previously. The purpose of this paper is to discuss the accentuated differences of various approaches to minimize IOL power miscalculations by describing a case report of a patient with excessive myopia as well as a review of the literature. PATIENT AND METHODS: A 50-year old lady presented for cataract surgery on her left eye after having PRK seven years ago elsewhere (refraction - 25.5 - 3.0/20 degrees, central keratometric power 43.0 diopters [D]). Central power before cataract extraction was measured to be 35.5 D (Zeiss Keratometer) and 36.5 D (TMS-1 topography analysis) and refraction was - 3.0 D (before onset of index myopia). Orbscan slit scanning topography analysis displayed an anterior surface power of 36.8 D and a posterior surface power of - 9.3 D. Total axial length was 31.93 mm (optical biometry using Zeiss IOL-Master). The contralateral eye after PRK suffering from a comparable excessive myopia had required an exchange of the IOL implant because of intolerable anisohyperopia of + 6.0 D after primary cataract extraction elsewhere. RESULTS: Corrected corneal power values for the left eye were calculated as follows: (1) spherical equivalent (SEQ) change at spectacle plane 19.0 D, (2) SEQ change at corneal plane 26.2 D, (3) separate consideration of anterior and posterior curvature 27.5 D, (4) consideration of the IOL power misprediction on the fellow eye 29.5 D, (5) subtraction of 24 % of the SEQ change at the spectacle plane from the actually measured keratometry value 29.7 D, (6) clinical estimate from regression analysis performed earlier 30.5 D, (7) change of anterior surface power 34.5 D. Deciding for a presumably "real" corneal power of 28.0 D the Haigis formula was used to aim for - 2.0 D since the patient preferred to read uncorrected. Thus, a 21.0 D IOL was implanted uneventfully in the capsular bag. The stable refraction postoperatively was - 3.5 - 1.0/20 degrees and visual acuity increased to 20/30. Therefore, the "real" power of that cornea must have been around 30 D. CONCLUSIONS: After corneal refractive surgery, various techniques to determine the current corneal power should be compared and the value around which results tend to cluster should be relied on to avoid hyperopia after cataract surgery with lens implantation. In those cases where keratometry and refraction before PRK/LASIK are available, the gold standard is still to subtract the change of the SEQ at the corneal plane from the preoperative central keratometric power, although in the present case report the subtraction of 24 % of the SEQ change at the spectacle plane from the measured corneal power value seemed to produce the best result. Pure subtraction of the SEQ change at the spectacle plane from the corneal power value before refractive surgery has to be avoided in eyes with excessive myopia. The most reliable corrected power value should be inserted in more than one modern third-generation formula (such as Haigis, Hoffer Q, Holladay 2, SRK/T) and the highest power IOL should be implanted. In all instances, the cataract surgeon has to make sure that the corrected K-reading is not wrongly re-converted within the IOL power calculation formula used.

Corneal Topography↗

Power absorption and production during slow, large-amplitude stretch-shorten cycle motions.

The purpose of this study was to determine the important predictors of power absorption and power production during slow, large-amplitude stretch-shorten cycle (SSC) motions. The relationship between power absorption (mean eccentric power output) and production (mean concentric power output) across different inertial loads was also investigated. Fifty-four subjects with a sporting background performed concentric (CBP) and rebound bench-presses (RBP) at 40% and 80% of their one-repetition maximum (1RM). The relationship between kinematic and kinetic variables and mean eccentric power and RBP mean power output was determined using correlation and multiple regression analysis. Maximal strength was found to be the best single predictor of power absorption, explaining between 44.2% and 69.1% of the variability that was associated with mean eccentric power output for 40% and 80% 1RM loads. Stretch velocity in combination with maximal strength was found to be the best two-predictor model of power absorption ( R(2)=83.7-97.3%). The best single predictor of SSC power production was found to be concentric mean power output ( R(2)=49.2-88.0%). The utilisation of the power absorbed during the power production phase differed across loads. It was suggested that as maximal strength is more trainable than speed, training to improve power absorption might emphasise maximal strength development. It was also suggested that SSC power output might benefit from training methods that focus on concentric force development. Further research is needed to evaluate these hypotheses and whether the findings of this study are similar for fast SSC motion.

Adult↗

The need for power, brain norepinephrine turnover and learning.

This experiment was designed to explore whether brain norepinephrine (NE) serves as a specific reward system for the power drive. Previous research has indicated that 3-methoxy-4-hydroxyphenyl glycol (MHPG), a urinary metabolite reflecting central NE turnover, is positively correlated with features of assertiveness which one might expect of a person high in the need for power (n power) or in a state of aroused power motivation. Twenty-seven male undergraduates, 13 of whom were high and 14 of whom were low in n power as assessed by a TAT measure, were recruited as subjects. Before and after the laboratory session, subjects voided all urine and concentrations of epinephrine, norepinephrine and MHPG were obtained from samples. The laboratory task consisted of 20 picture-word pairs in which the subject had to learn to anticipate the word associated with each picture before the word was presented. Five pairs of stimuli in each of the following picture-word combinations were presented 12 times: neutral-neutral, neutral-power, power-neutral and power-power. The results revealed that, as predicted, subjects high in n power learn most power-related material faster than subjects low in n power. The need for achievement is unrelated to the learning of any picture-word pairs. The neurochemical data indicated that subjects maintaining a relatively high MHPG excretion rate during the experiment who were also high in n power showed the greatest mastery of power related compared with neutral picture-word pairs. These findings are consistent with the hypothesis that brain NE turnover is specifically related to the learning of power-related responses in subjects high in n power.

Assertiveness↗

The use of quantitative temperature images to predict the optimal power for focused ultrasound surgery: in vivo verification in rabbit muscle and brain.

In this study, we investigated the use of MRI-derived thermal imaging for determining the exposure parameters for focused ultrasound (FUS) surgery. Since the temperature rise induced by a FUS beam scales linearly with power, the temperature maps acquired during subthreshold sonications can be used to determine the power necessary to produce thermal tissue damage with a desired size. Thermal images acquired during multiple sonications delivered at different locations in rabbit thigh muscle and brain tissue in vivo were analyzed to test this hypothesis. First, the linearity of the induced temperature rise with the acoustic power was tested. Next, the temperature maps acquired during preliminary low power sonications were scaled up until the estimated size of the tissue damage was equal to the tissue damage size of subsequent high power sonications. A threshold thermal dose was used to estimate the onset of thermal damage. The predicted power (based on amount of scaling required to reach the target size) was then compared to the true high power value. Overall, the temperature rise varied linearly with power (slope of deltaThigh/deltaTlow vs Power(high)/Power(low) = 0.97, 0.93 for pairs of sonications at each location in brain, muscle). The predicted power matched the true high power in the brain sonications (slope = 1.04). The predicted power underestimated the true high power in the muscle sonications (slope = 0.87). This under-prediction was due to a deviation from linearity in those cases where tissue damage was detected in subsequent MR images (slope of deltaThigh/deltaTlow vs Power(high)/Power(low) = 1.02, 0.84 for no tissue damage, tissue damage). The source of this deviation was not clear from these experiments. Even with this underestimation of the power, this method will be useful because it will allow an estimate of the proper power to use during FUS surgery without exact knowledge of the tissue parameters.

Animals↗

Vascularity of hepatocellular carcinoma: assessment with contrast-enhanced second-harmonic versus conventional power Doppler US.

PURPOSE: To compare contrast material-enhanced harmonic power Doppler ultrasonography (US) with conventional power Doppler US in depicting the vascularity of hepatocellular carcinoma (HCC). MATERIALS AND METHODS: Twenty patients with nodular HCCs (2.6-13.2 cm in diameter; mean diameter, 4.8 cm) were prospectively examined with both conventional and harmonic power Doppler US. US was performed with a 2-4-MHz curved linear-array transducer according to a standard examination protocol (1,000-Hz pulse repetition frequency, medium wall filter, and power gain of 55%-84% for conventional power Doppler US; 700-Hz pulse repetition frequency, low wall filter, and power gain of 95%-98% for harmonic power Doppler US). Serial, dynamic scans were obtained before intravenous injection of the contrast agent (SH U 508A) and at 30, 60, 90, 120, 180, 240, and 300 seconds after injection with both techniques. RESULTS: The number of intratumoral power Doppler US signals was similar with both techniques at 30-90 seconds after contrast agent injection; however, after 90 seconds, conventional power Doppler US depicted significantly more signals than did harmonic power Doppler US. Harmonic power Doppler US was superior to conventional power Doppler US in terms of power Doppler artifacts such as "blooming" or motion-related artifacts. CONCLUSION: Although the effective enhancement duration is relatively short compared with that for conventional power Doppler US, contrast-enhanced harmonic power Doppler US can be effective in evaluating the vascularity of HCCs because of the advantage of fewer power Doppler artifacts.

Aged↗

Procedure for determining maximum sustainable power generated by microbial fuel cells.

Power generated by microbial fuel cells is computed as a product of current passing through an external resistor and voltage drop across this resistor. If the applied resistance is very low, then high instantaneous power generated by the cell is measured, which is not sustainable; the cell cannot deliver that much power for long periods of time. Since using small electrical resistors leads to erroneous assessment of the capabilities of microbial fuel cells, a question arises: what resistor should be used in such measurements? To address this question, we have defined the sustainable power as the steady state of power delivery by a microbial fuel cell under a given set of conditions and the maximum sustainable power as the highest sustainable power that a microbial fuel cell can deliver under a given set of conditions. Selecting the external resistance that is associated with the maximum sustainable power in a microbial fuel cell (MFC) is difficult because the operator has limited influence on the main factors that control power generation: the rate of charge transfer at the current-limiting electrode and the potential established across the fuel cell. The internal electrical resistance of microbial fuel cells varies, and it depends on the operational conditions of the fuel cell. We have designed an empirical procedure to predict the maximum sustainable power that can be generated by a microbial fuel cell operated under a given set of conditions. Following the procedure, we change the external resistors incrementally, in steps of 500 omega every 10, 60, or 180 s and measure the anode potential, the cathode potential, and the cell current. Power generated in the microbial fuel cell that we were using was limited by the anodic current. The anodic potential was used to determine the condition where the maximum sustainable power is obtained. The procedure is simple, microbial fuel cells can be characterized within an hour, and the results of the measurements can serve many purposes, such as: (1) estimating power generation in various MFCs, (2) comparing power generation in MFCs using different electroactive reactants, (3) quantifying the effects of the operational regime on the power generation in MFCs, and finally, (4) the purpose for which the procedure was designed, optimizing the performance of existing MFCs.

Bacteria↗

Low-power holmium laser for the management of urinary tract calculi, structures, and tumors.

BACKGROUND AND PURPOSE: Introduction of the holmium laser has provided an indispensable tool for the management of urinary tract stones, strictures, and superficial urothelial tumors. While full-power holmium lasers are required for laser resection of the prostate, lower-power devices can be utilized for all cases of stone fragmentation and stricture incision and most cases of superficial urothelial tumors. Herein, we report our initial experience in utilizing a low-power holmium laser in our endourologic practice. PATIENTS AND METHODS: Over a 6-month period, we have utilized both low-power (25 W) and full-power (80 W) holmium lasers to fragment urinary tract stones, incise ureteral or urethral strictures, and ablate superficial urothelial tumors. A series of 80 consecutive patients were assessed prospectively. Laser fibers with a diameter of 200 microm and 365 microm were employed with power settings of 6.4 to 10 W. Laser fiber size and power settings were similar for the low- and full-power devices. RESULTS: Overall, 95% of the stones were completely fragmented, with a stone-free rate at 3 months of 92%. All strictures were incised, with a 91% patency rate at 3 months. Complete tumor ablation was attained in 70%, with a tumor-free rate of 60% at 3 months. Results were equivalent for the low- and full-power lasers. The 200-microm laser fiber allowed adequate access throughout the upper urinary tract during flexible ureteroscopy and flexible nephroscopy. The 365-microm laser fiber was employed via rigid and semirigid endoscopes. CONCLUSIONS: A low-power holmium laser supplies adequate fragmentation and incision power for virtually all endourologic cases. It also provides ablative power in most situations. The only current urologic application that cannot be performed with the low-power device is laser prostatic resection, which requires 60 to 80 W of power. The reduced-power holmium laser should be considered as a low-cost alternative for the management of urinary tract stones, strictures, and urothelial tumors, especially in centers where laser prostatic resection is not performed.

Adult↗

Impact of muscle power and force on gait speed in disabled older men and women.

BACKGROUND: The purpose of this study was to explore the relationship between muscle power output at different external resistances and performance of functional tasks. The authors hypothesized that power at 40% skeletal muscle 1 repetition maximum (1RM), in which contraction velocity is high, would explain more of the variability in tasks such as level walking than would peak power or 1RM strength, in which contraction velocity is lower. METHODS: Participants were men and women (n = 48; ages 65-91 years) with physical disability as evidenced by 2 or more deficits on the Medical Outcomes Study Short Form physical function subscale or a score of 9 or less on the Established Populations for the Epidemiologic Studies of the Elderly short physical performance battery. Muscle strength (1RM) was measured using a bilateral leg press exercise, and power output was determined by selecting the highest power output from 6 different contraction velocities: 40%, 50%, 60%, 70%, 80%, and 90% 1RM. Functional performance tasks consisted of habitual gait velocity (HGV) and stair climb (SC) and chair rise (CR) performance. Separate linear regression models were fit for each of the 3 dependent variables (SC, CR, HGV) using 1RM strength, power at 70% 1RM, and power at 40% 1RM as independent variables. All models were adjusted for age, body mass, and sex. RESULTS: Lower extremity power at 70% and 40% 1RM demonstrated greater associations with SC and HGV than did 1RM strength, whereas power at 40% 1RM demonstrated similar or stronger associations with all functional tasks compared with 1RM strength. Power at 40% 1RM explained the same or more of the variability in SC (R(2) = .42 [regression coefficient = -.169 +/- .06] vs .43 [-.206 +/- .071]), CR (R(2) = .28 [-.154 +/- .057] vs .24 [-.152 + .070]) and HGV (R(2) = .59 [.214 + .37] vs .51 [.223 +/- .049]) compared with power at 70% 1RM. Power at 40% 1RM explained more of the variability in the lower intensity (HGV) compared with the higher intensity (SC or CR) functions. CONCLUSIONS: Power output at 40% of 1RM explained more of the variability in HGV than did power at 70% 1RM, suggesting that measures such as HGV that require a lower percentage of maximal strength to perform might be more sensitive to differences in contraction velocity. Because HGV is highly predictive of subsequent disability, future studies should evaluate the determinants of muscle power output at low external resistances.

Aged↗

Monitoring radiant power in the critically ill newborn under a radiant warmer.

To evaluate radiant power received by infants under radiant warmers, 11 neonates (mean gestational age 32.2 weeks, mean weight 1.50 kg) were monitored. A wattmeter was used to evaluate warmer power (watts), and a thermopile placed at bed level was used to correlate warmer power to radiant power density received (mw/cm2). Warmer power ranged from 133-301 watts. A linear relationship existed between warmer power and radiant power density received (r = 0.97, p < 0.001). After establishing that radiant power delivery could be monitored with a wattmeter, this technique was used to quantitate radiant power in a small series of infants with and without a plastic shield. Radiant power density received decreased in all infants when shielded (mean 14.6-11.2 mw/cm2, p < 0.01). This study demonstrates: (1) radiant warmer power can be monitored with a wattmeter; (2) warmer power correlates to radiant power density received; and (3) radiant power monitoring can be used to evaluate radiant power demands in specific clinical situations.

Apnea↗

The two power limits conditioning step frequency in human running.

1. At high running speeds, the step frequency becomes lower than the apparent natural frequency of the body's bouncing system. This is due to a relative increase of the vertical component of the muscular push and requires a greater power to maintain the motion of the centre of gravity, Wext. However, the reduction of the step frequency leads to a decrease of the power to accelerate the limbs relatively to the centre of gravity, Wint, and, possibly, of the total power Wtot = Wext + Wint. 2. In this study we measured Wext using a force platform, Wint by motion picture analysis, and calculated Wtot during human running at six given speeds (from 5 to 21 km h-1) maintained with different step frequencies dictated by a metronome. The power was calculated by dividing the positive work done at each step by the duration of the step (step-average power) and by the duration of the positive work phase (push-average power). 3. Also in running, as in walking, a change of the step frequency at a given speed has opposite effects on Wext, which decreases with increasing step frequency, and Wint, which increases with frequency; in addition, a step frequency exists at which Wtot reaches a minimum. However, the frequency for a minimum of Wtot decreases with speed in running, whereas it increases with speed in walking. This is true for both the step-average and the push-average powers. 4. The frequency minimizing the step-average power equals the freely chosen step frequency at about 13 km h-1: it is higher at lower speeds and lower at higher speeds. The frequency minimizing the push-average power approaches the freely chosen step frequency at high speeds (around 22 km h-1 for our subjects). 5. It is concluded that the increase of the vertical push does reduce the step-average power, but that a limit is set by the increase of the push-average power. Between 13 and 22 km h-1 the freely chosen step frequency is intermediate between a frequency minimizing the step-average power, eventually limited by the maximum oxygen intake (aerobic power), and a frequency minimizing the push-average power, set free by the muscle immediately during contraction (anaerobic power). The first need prevails at the lower speed, the second at the higher speed.

Biomechanical Phenomena↗

Effects of velocity on upper to lower extremity muscular work and power output ratios of intercollegiate athletes.

OBJECTIVES: Peak torque expresses a point output which may, but does not always, correlate well with full range output measures such as work or power, particularly in a rehabilitating muscle. This study evaluates isokinetic performance variables, particularly (a) flexor to extensor work and power output ratios of upper and lower extremities and (b) overall upper to lower extremity work and power ratios, in intercollegiate athletes. The purpose was to ascertain how speeds of 30 and 180 degrees/s influence agonist to antagonist ratios for torque, work, and power and to determine the effects of these speeds on upper to lower limb flexor (F), extensor (E), and combined (F + E) ratios, as a guide to rehabilitation protocols and outcomes after injury. METHODS: Twenty seven athletic men without upper or lower extremity clinical histories were tested isokinetically at slow and moderately fast speeds likely to be encountered in early stages of rehabilitation after injury. Seated knee extensor and flexor outputs, particularly work and power, were investigated, as were full range elbow extensor and flexor outputs. The subjects were morphologically similar in linearity and muscularity (coefficient of variation 4.17%) so that standardisation of isokinetic outputs to body mass effectively normalised for strength differences due to body size. Peak torque (N.m/kg), total work (J/kg), and average power (W/kg) for elbow and knee flexions and extensions were measured on a Cybex 6000 isokinetic dynamometer. With respect to the raw data, the four test conditions (F at 30 degrees/s; E at 30 degrees/s; F at 180 degrees/s; E at 180 degrees/s) were analysed by one way analysis of variance. Reciprocal (agonist to antagonist) F to E ratios of the upper and lower extremities were calculated, as were upper to lower extremity flexor, extensor, and combined (F + E) ratios. Speed related differences between the derived ratios were analysed by Student's t tests (related samples). RESULTS: At the speeds tested all torque responses exhibited velocity related decrements at rates that kept flexor to extensor ratios and upper to lower extremity ratios constant (p > 0.05) for work and power. All upper extremity relative torque, work, and power flexion responses were equal to extension responses (p > 0.05) regardless of speed. Conversely, all lower extremity relative measures of torque, work, and power of flexors were significantly lower than extensor responses. In the case of both upper and lower extremities, work and power F to E ratios were unaffected by speed. Moreover, increasing speed from 30 to 180 degrees/s had no effect on upper to lower extremity work and power ratios, whether for flexion, extension, or flexion and extension combined. CONCLUSIONS: Peak torque responses may not adequately reflect tension development through an extensive range of motion. Total work produced and mean power generated, on the other hand, are highly relevant measures of performance, and these, expressed as F to E ratios, are unaffected by speeds of 30 and 180 degrees/s, whether for upper or lower extremities or for upper to lower extremities. In this sample, regardless of speed, the upper extremity produced 55% of the work and 39% of the power of the lower extremity, when flexor and extensor outputs were combined. Injured athletes are, in the early stages of function restoration, often not able to exert tension at fast speeds. An understanding of upper to lower extremity muscular work and power ratios has important implications for muscle strengthening after injury. Knowledge of normal upper to lower extremity work and power output ratios at slow to moderately fast isokinetic speeds is particularly useful in cases of bilateral upper (or lower) extremity rehabilitation, when the performance of a contralateral limb cannot be used as a yardstick.

Adult↗

Power of test considerations for beef cattle experiments: a review.

The use of power tests in the planning and design of beef cattle experiments provides critical information on sample sizes necessary to detect treatment differences at a predetermined significance (alpha) level. Retrospective power analysis provides additional information about previous experiments that may be helpful in designing subsequent investigations. However, in retrospective power analyses, power is inversely related to observed significance level. Benefits of prospective and retrospective power analyses in beef cattle experiments are similar to those for other species; however, because of differences in the methods and conditions involved, considerations for the use of power test procedures are specific for beef cattle research. Retrospective power analyses were conducted on 78 published experiments and on two unpublished experiments. Experiments were compiled into categories that represented group (or pen) feeding, individual feeding, and metabolism studies. Estimated power in pen feeding experiments using randomized block designs (RBD, n = 30) was less than 0.80 for ADG and feed efficiency (FE), but not different from 0.80 for completely random designs (CRD, n = 4). Furthermore, estimated power was less for ADG than for FE in both design types. For individual feeding experiments using RBD (n = 4), power was not different from 0.80 for either ADG or FE; however, for CRD (n = 18), power was less than 0.80 for both ADG and FE. Power was similar for ADG and FE for both RBD and CRD in individual feeding experiments. In metabolism experiments, estimated power for nitrogen retention was less than 0.80 for Latin square designs (n = 20) but not for CRD (n = 4). Comparisons of power between experimental design types were likely influenced by the number of experiments involved. These results indicate that retrospective power in beef cattle experiments is affected by design type, and response variable measured.

Animal Nutritional Physiological Phenomena↗

Power responses of a rowing ergometer: mechanical sensors vs. Concept2 measurement system.

The aim of this study was to compare the power provided by a recent ergometer with the power developed by the rower determined using mechanical sensors set on the same apparatus. Six rowers and six non-rowers performed a power graded test and an all-out start on an instrumented ergometer (Concept2 system, model D, Morrisville, VT, USA). Power values displayed by the ergometer were recorded with a specific software. A strain gauge placed near the handle and a position sensor installed on the chain allowed the calculation of the power developed by the rower. Power values provided by the ergometer were strongly correlated to those determined with a direct measurement and calculation of power. However, power values given by the Concept2 system were lower (- 17.4 to - 72.4 W) than those calculated using mechanical sensors. This difference in power measurements was lower at a steady pace and for rowers. The Concept2 system underestimates the power produced by the rower by approximately 25 W. This difference in power seems to be independent of the level of power developed but increases with variations in intensity and pace. The deletion of the first strokes following changes in power production allows to limit this phenomenon. According to the use of the power parameter in the experimental design, it could be appropriate to correct values provided by the Concept2 ergometer.

Adult↗

Power, muscular work, and external forces in cycling.

Cycling performance is affected by the interaction of a number of variables, including environment, mechanical, and human factors. Engineers have focused on the development of more efficient bicycles. Kinesiologists have examined cycling performance from a human perspective. This paper summarizes only certain aspects of human ergonomics of cycling, especially those which are important for the recent current research in our departments. Power is a key to performance of physical work. During locomotion an imaginary flow of energy takes place from the metabolism to the environment, with some efficiency. The 'useful' mechanical muscle power output might be used to perform movements and to do work against the environment. The external power is defined as the sum of joint powers, each calculated as the product of the joint (net) moment and angular velocity. This definition of external power is closely related to the mean external power as applied to exercise physiology: the sum of joint powers reflects all mechanical power which in principle can be used to fulfil a certain task. In this paper, the flow of energy for cycling is traced quantitatively as far as possible. Studies on the total lower limb can give insight into the contribution of individual muscles to external power. The muscle velocity (positive or negative) is obtained from the positions and orientations of body segments and a bar linkage model of the lower limb. The muscle activity can be measured by electromyography. In this way, positive and negative work regions in individual muscles are identified. Synergy between active agonistic/antagonistic muscle groups occurs in order to deliver external power. Maximum power is influenced by body position, geometry of the bicycle and pedalling rate. This has to be interpreted in terms of the length-tension and force-velocity-power relationships of the involved muscles. Flat road and uphill cycling at different saddle-tube angles is simulated on an ergometer. The measured pedal forces (magnitude and direction) are only dependent on the intersegmental orientation of saddle tube, crank position, upper and lower leg, and foot. The changed direction of the gravitational force with respect to the saddle-tube does not interfere with the co-ordinated force production pattern. During locomotory cycling at constant speed the external power is mainly used to overcome the aerodynamic friction force. This force and the rolling resistance are determined by coasting down experiments, yielding the external power.(ABSTRACT TRUNCATED AT 400 WORDS)

Bicycling↗

Measurement of the muscle power of the toes in female marathon runners using a toe dynamometer.

The aim of this study was to investigate the relationship between the strength of the foot muscles that control the toes and disorders such as shin splint. In order to this, we designed and built a toe dynamometer to compare the muscle power exerted through the toes in top female marathon runners and age-matched women not involved in sports. The subjects were 12 top-level female marathon runners (Group A) and 37 student nurses who were not involved in sports (Group B). We devised a dynamometer to measure the total power exerted by the flexor muscles of the 5 toes of a single foot (total flexor power) and the combined power of the abductors of the big (1st) and little (5th) toes (abductor power). In Group A, the total flexor power was 14.3 +/- 5.3 kg in the right foot and 15.4 +/- 4.7 kg in the left foot. The abductor power was 1.9 +/- 1.8 kg in the right foot and 2.2 +/- 1.9 kg in the left foot. In Group B, total flexor power was 18.3 +/- 6.7 kg in the right foot, while the abductor power was 1.9 +/- 1.7 kg. The subjects from Group A with an arch index < 1.0 (n = 8) or > 1.0 (n = 4) were respectively classified as Group I and Group II. In Group I, total flexor power was 14.9 +/- 5.3 kg (right) and 15.5 +/- 5.2 kg (left), while the abductor power was 2.6 +/- 1.9 kg (right), and 3.1 +/- 1.7 kg (left). In Group II, the total flexor power was 13.2 +/- 5.8 kg (right) and 15.1 +/- 4.2 kg (left), while the abductor power was 0.7 +/- 0.6 kg (right) and 0.3 +/- 0.2 kg (left). The abductor power of toes was significantly lower in Group II than in Group I. The incidence of posteromedial shin pain was higher in Group II (75.0%) than in Group I (12.5%).

Adolescent↗