PubMed Health⌕ Search

SEARCH · PubMed Health

Results for “CORNEOMANDIBULAR REFLEX”

Explore indexed PubMed citations for clinical trials, systematic reviews and public health research. Read source abstracts and follow each citation to its original PubMed record.

Quote a phrase for an exact phrase match. Source license links do not imply unrestricted reuse.

21 records · Page 2Linked to original sources

Influence of dopamine and disease severity on primitive reflexes in Parkinson's disease.

Several primitive reflexes are common in patients with Parkinson's disease (PD), but can also be noted in patients who have diffuse cerebral degeneration. The glabellar response is present in virtually all patients with PD and this reflex has been of theoretical interest in PD. It has been suggested that the glabellar response is related to inhibition via dopamine pathways. We examined changes in several primitive reflexes as a function of the plasma dopamine level and the severity of PD. The probability of observing these reflexes did not vary with dopamine levels, but the corneomandibular and palmomental reflexes were significantly more likely to be present in patients with advanced disease. Our findings confirm that primitive reflexes are prominent in PD and suggest that they may be secondary to extrapyramidal disease.

Age Factors↗

Primitive reflexes in Down's syndrome.

The clinical value and prevalences of three primitive reflexes, i.e. the palmomental, the snout, and the corneomandibular, were examined in 30 institutionalized patients with Down's syndrome and the results were compared with those in a control group. The prevalence of palmomental reflex was clearly higher, i.e. 47% (31,63) in DS as compared to 7% (2,16) in controls (confidence limits, P = 0.9, is given in the parenthesis) (P = 0.0001). The prevalences of the snout reflex in the DS and control group were estimated to be 14% (5,29) and 0% (0,6) respectively (P = 0.02). The corneomandibular reflex was found unreliable in DS, mainly because of lack of cooperation. Neither the palmomental nor the snout reflex correlated well with the degree of mental retardation. No correlation of reflex incidence with age was demonstrated for the palmomental reflex. The prevalence of the snout reflex in DS patients less than 35 years was estimated to be 0% (0,18). This is significantly (P less than 0.05) less than the prevalence of 29% (10,54), found in the group older than 35 years of age. The possible value of the snout reflex as a sign of dementia in Down's syndrome is discussed.

Adult↗

Primitive (developmental) reflexes and diffuse cerebral dysfunction in schizophrenia and bipolar affective disorder: overrepresentation in patients with tardive dyskinesia.

Primitive (developmental) reflexes are present in fetal and infant life, but disappear in adulthood. Their elicitation in later life usually occurs in association with cortical or diffuse cerebral dysfunction and suggests a new approach to the issue of whether tardive dyskinesia is particularly likely to occur in patients with organic brain disorder(s). Sixty-six patients with schizophrenia (age range 50-86) and 18 with bipolar affective disorder (age range 40-77) were assessed for the presence of involuntary movements and for the release of the grasp, palmomental, snout, corneomandibular, and glabellar reflexes. In each diagnostic group, patients with involuntary movements showed a significant excess of primitive reflexes in comparison with otherwise indistinguishable patients without such movements. These results complement recent reports that similar patients with involuntary movements also show greater cognitive impairment and point anew to an association between the presence of tardive dyskinesia and of organic brain dysfunction. They raise again the issue of whether or not such dysfunction may be a consequence of neurodevelopmental abnormality rather than of neurodegenerative processes.

Aged↗