PubMed Health⌕ Search

SEARCH · PubMed Health

Results for “GANGLIA, SPINAL”

Explore indexed PubMed citations for clinical trials, systematic reviews and public health research. Read source abstracts and follow each citation to its original PubMed record.

Quote a phrase for an exact phrase match. Source license links do not imply unrestricted reuse.

At least 37 records · Page 2Linked to original sources
PubMed1985

Choline acetyltransferase and acetylcholinesterase in canine spinal ganglia: increase of choline acetyltransferase activity following sciatic nerve lesion.

Activities of choline acetyltransferase (ChAT) and acetylcholinesterase (AChE) were measured in the dorsal spinal ganglia, the dorsal spinal root and the spinal cord of the normal adult dogs and following one side transection of the sciatic nerve in the intervals 5, 10, 15 and 21 days respectively. In the spinal ganglia of normal dogs very low ChAT activity was found; it was three orders lower than AChE activity. Within 5-10 days after the nerve section ChAT activity increased almost five times in the spinal ganglia while AChE activity remained without any changes. The elevation of ChAT activity correlated with that in the dorsal roots at 15th day and in the dorsal spinal cord at 21st day after the nerve section. Histochemical "direct-colouring" thiocholine method showed AChE-positive cells were distributed mainly in the peripheral area of the spinal ganglia. The spinal ganglion cells ranged from intensely AChE-positive to AChE-negative without correlation between cell size and AChE activity. The ChAT activity changes were evaluated in correlation to the cholinergic function in the spinal ganglion neurons.

Acetylcholinesterase↗
PubMed1980

Effect of ischemia on acetylcholinesterase activity and its molecular forms in the dog spinal cord, spinal ganglia and sciatic nerve.

Partial ischemia of the spinal cord was produced by the ligature of the abdominal aorta twice for 40 minutes with a 40 min. recirculation interval. At the end of the ischemic period acetylcholinesterase (AChE. EC 3.1.1.7) activity increased significantly in the lumbosacral part of the spinal cord but simultaneously decreased in the spinal ganglia; There was no significant change in the sciatic nerve. After 48 hours of recovery AChE activity returned to normal in the sacral part of the spinal cord and in the spinal ganglia, but a less expressive increase remained in the lumbal part. Electrophoretic separation of AChE on the polyacrylamide gel gave in intact control dogs: three or four molecular forms in the spinal cord, five in the spinal ganglia and two molecular forms in the sciatic nerve. Ischemia increased the relative content of the lower molecular forms and often a new low molecular form appeared.

Acetylcholinesterase↗