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The genome sequence of Veronica verna L., 1753 (Lamiales: Plantaginaceae).

We present a genome assembly of Veronica verna (Spring Speedwell; Streptophyta; Magnoliopsida; Lamiales; Plantaginaceae). The genome sequence has a total length of 463.88 megabases. Most of the assembly (98.85%) is scaffolded into 8 chromosomal pseudomolecules. The mitochondrial sequence has a length of 311.81 kilobases and the plastid genome assembly has a length of 149.82 kilobases. Gene annotation of this assembly on Ensembl identified 22 903 protein-coding genes. This assembly was generated as part of the Darwin Tree of Life project, which produces reference genomes for eukaryotic species found in Britain and Ireland.

Asterales↗

The genome sequence of Filago lutescens Jord., 1846 (Asterales: Asteraceae).

We present a genome assembly of Filago lutescens (Red-tipped Cudweed; Streptophyta; Magnoliopsida; Asterales; Asteraceae). The assembly consists of two haplotypes with total lengths of 648.45 megabases and 646.22 megabases. Most of haplotype 1 (99.77%) is scaffolded into 14 chromosomal pseudomolecules. Haplotype 2 was assembled to scaffold level. The mitochondrial sequence has a length of 225.84 kilobases and the plastid genome assembly has a length of 151.54 kilobases. Gene annotation of this assembly on Ensembl identified 38 942 protein-coding genes. This assembly was generated as part of the Darwin Tree of Life project, which produces reference genomes for eukaryotic species found in Britain and Ireland.

Asterales↗

The genome sequence of Hypericum androsaemum L., 1753 (Malpighiales: Hypericaceae).

We present a genome assembly of Hypericum androsaemum (Tutsan; Streptophyta; Magnoliopsida; Malpighiales; Hypericaceae). The genome sequence has a total length of 384.54 megabases. Most of the assembly (99.96%) is scaffolded into 20 chromosomal pseudomolecules. The mitochondrial sequences have lengths of 138.63, 75.57, 98.15 and 103.38 kilobases and the plastid genome assembly has a length of 165.0 kilobases. This assembly was generated as part of the Darwin Tree of Life project, which produces reference genomes for eukaryotic species found in Britain and Ireland.

Hypericum androsaemum↗

The genome sequence of Aquilegia vulgaris L., 1753 (Ranunculales: Ranunculaceae).

We present a genome assembly of Aquilegia vulgaris (Columbine; Streptophyta; Magnoliopsida; Ranunculales; Ranunculaceae). The assembly consists of two haplotypes with total lengths of 296.10 megabases and 289.22 megabases. Most of haplotype 1 (98.81%) is scaffolded into 7 chromosomal pseudomolecules. Most of haplotype 2 (94.35%) is scaffolded into 7 chromosomal pseudomolecules. The mitochondrial sequences have lengths of 388.22 and 83.91 kilobases and the plastid genome assembly has a length of 161.5 kilobases. Gene annotation of this assembly on Ensembl identified 23 898 protein-coding genes. This assembly was generated as part of the Darwin Tree of Life project, which produces reference genomes for eukaryotic species found in Britain and Ireland.

Aquilegia vulgaris↗

The genome sequence of Frangula alnus Mill., 1768 (Rosales: Rhamnaceae).

We present a genome assembly of Frangula alnus (alder buckthorn; Streptophyta; Magnoliopsida; Rosales; Rhamnaceae). The assembly consists of two haplotypes with total lengths of 279.06 megabases and 281.25 megabases. Most of haplotype 1 (99.91%) is scaffolded into 10 chromosomal pseudomolecules. Most of haplotype 2 (99.91%) is scaffolded into 10 chromosomal pseudomolecules. The mitochondrial sequence has a length of 492.03 kilobases and the plastid genome assembly has a length of 161.23 kilobases. This assembly was generated as part of the Darwin Tree of Life project, which produces reference genomes for eukaryotic species found in Britain and Ireland.

Frangula alnus↗

The genome sequence of Quercus petraea Liebl., 1784 (Fagales: Fagaceae).

We present a genome assembly of Quercus petraea (sessile oak; Streptophyta; Magnoliopsida; Fagales; Fagaceae). The assembly consists of two haplotypes with total lengths of 823.57 megabases and 815.09 megabases. Most of haplotype 1 (99.41%) is scaffolded into 12 chromosomal pseudomolecules. Haplotype 2 was assembled to scaffold level. The mitochondrial sequence has a length of 349.29 kilobases and the plastid genome assembly has a length of 161.18 kilobases. Gene annotation of this assembly on Ensembl identified 32 253 protein-coding genes. This assembly was generated as part of the Darwin Tree of Life project, which produces reference genomes for eukaryotic species found in Britain and Ireland.

Fagales↗

Herbs as medicines.

Herbs and related products are commonly used by patients who also seek conventional health care. All physicians, regardless of specialty or interest, care for patients who use products that are neither prescribed nor recommended. Some herbs have been extensively studied, but little is known about others. When a patient asks for advice regarding the use of a particular herb, how should a physician respond? Similarly, how does a physician determine if a patient's symptoms are caused by a "remedy"? This review attempts to answer these questions by investigating pertinent definitions, the history of herbs in medicine, epidemiology and prevalence of herbal use, and relevant psychosocial issues.

Drug Costs↗

Herbal remedies in psychiatric practice.

Patients' use of alternative and complementary health services has created a need for physicians to become informed about the current literature regarding these treatments. Herbal remedies may be encountered in psychiatric practice when they are used to treat psychiatric symptoms; produce changes in mood, thinking, or behavior as a side effect; or interact with psychiatric medications. English-language articles and translated abstracts or articles (where available) found on MEDLINE and sources from the alternative/complementary health field were reviewed. Each herb was assessed for its safety, side effects, drug interactions, and efficacy in treating target symptoms or diagnoses. A synopsis of the information available for each herb is presented. In many cases the quantity and quality of data were insufficient to make definitive conclusions about efficacy or safety. However, there was good evidence for the efficacy of St John's wort for the treatment of depression and for ginkgo in the treatment of memory impairment caused by dementia. More research is required for most of the herbs reviewed, but the information published to date is still of clinical interest in diagnosing, counseling, and treating patients who may be taking botanical remedies.

Anti-Anxiety Agents↗

Thymos primer.

Explore the source record for details and available documents.

Egypt↗

Herbal intoxication. Psychoactive effects from herbal cigarettes, tea, and capsules.

Herbal preparations, designed to be smoked or ingested for "health and happiness", are promoted as legal hallucinogens, euphoriants, and marihuana substitutes. A total of 25 psychoactive substances have been identified in these products, and a number of intoxications have resulted from their short- or long-term use. Physicians should be alerted to the nature of these effects when taking drug histories, and their possible role in the causation of medical complaints should be considered.

Adult↗

Review of recent placebo-controlled trials utilizing phytotherapeutic agents for treatment of BPH.

BACKGROUND: In order to assess the efficacy of phytotherapeutic agents for the treatment of benign prostatic hyperplasia (BPH), a review of recently published double-blind placebo-controlled trials was undertaken. METHODS: Only those studies reviewed by the Other Medical Therapies Committee of the Fourth International Consultation on BPH were included. RESULTS: These studies suggest a possible benefit for the use of phytotherapeutic preparations in the treatment of BPH. CONCLUSIONS: These studies need to be confirmed in larger long-term placebo-controlled studies in order to ascertain the true efficacy of these agents.

Anti-Bacterial Agents↗

Evidence for demethylation of syringyl moieties in archaeological wood using pyrolysis-gas chromatography/mass spectrometry.

Archaeological oak (Quercus sp.) wood samples, ranging from 16(th) C. AD to 6000 BP, were studied using flash pyrolysis-gas chromatography/mass spectrometry to obtain insight into angiosperm lignin degradation. The pyrolysates revealed evidence of a number of 3-methoxy-1,2-benzenediol derivatives, methoxycatechols, directly related to 2,6-dimethoxyphenol, syringyl, moieties which are characteristic building blocks of angiosperm lignin. Mass spectra and mass chromatograms of these compounds are reported. The finding of these characteristic pyrolysis products in well-preserved archaeological wood provides unequivocal evidence that demethylation of syringyl units occurs very early in wood degradation. It is highly likely that the absence of abundant 3-methoxy-1, 2-benzenediols in degrading plant materials containing angiosperm lignin relates to the lability of these newly formed moieties.

Archaeology↗

A simple structured model for maintenance, biomass formation, and ajmalicine production by nondividing Catharanthus roseus cells.

The stoichiometry of maintenance and carbohydrate storage as well as ajmalicine production kinetics of non-dividing Catharanthus roseus cells in the second stage of a two-stage batch process were investigated. For the mathematical description of these processes, a simple structured model with 5 parameters is proposed. In the model the biomass is divided in two compartments: active biomass and storage carbohydrates. In induction medium (standard medium without phosphate, nitrogen and hormones), biomass formation, glucose consumption, and CO(2) production appeared to be constant in time. Therefore, it is assumed that the active biomass level is constant. The maintenance coefficient m(S), and the yield of storage carbohydrates on glucose Y(SC) were optimized by fitting the model on experimental data: 0.003 C-mol/C-mol/h and 0.82 C-mol/C-mol, respectively. Production kinetics were incorporated in this model and related to the active biomass fraction. The maximum specific ajmalicine production rate q(p)(max) was fitted on the data: 7.5 micromol/C-mol/h. The model was tested at several different experimental conditions, and proved to describe the experimental results adequately. An independent experiment at a very high cell density in order to obtain maximum product formation was used to validate the model. It provided a satisfactory description of the results, but the final ajmalicine concentration (198 micromol/L after 18 days) was lower than the calculated maximum, due to accumulation of inhibiting gaseous metabolites.

Biomass↗

Inhibition of enteric parasites by emulsified oil of oregano in vivo.

Oil of Mediterranean oregano Oreganum vulgare was orally administered to 14 adult patients whose stools tested positive for enteric parasites, Blastocystis hominis, Entamoeba hartmanni and Endolimax nana. After 6 weeks of supplementation with 600 mg emulsified oil of oregano daily, there was complete disappearance of Entamoeba hartmanni (four cases), Endolimax nana (one case), and Blastocystis hominis in eight cases. Also, Blastocystis hominis scores declined in three additional cases. Gastrointestinal symptoms improved in seven of the 11 patients who had tested positive for Blastocystis hominis.

Adult↗