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Productivity growth in health-care delivery.

OBJECTIVES: The authors compute and compare productivity growth in the health-care sectors for a sample of Organization for Economic Cooperation and Development countries over the period from 1974 to 1989. The authors compute Malmquist productivity indexes, which allow productivity growth to be decomposed into efficiency changes and technical change. These indexes also allow the use of primary quantity data (recently available from the Organization for Economic Cooperation and Development), rather than expenditure data, which the authors argue reduces bias resulting from distorted prices. METHODS: The authors specify two models. The first model focuses on the hospital sector; inputs include physicians and medical care beds, whereas outputs are the "intermediate" type used in hospital efficiency studies, namely, inpatient days and discharges. RESULTS: For the 19 countries with complete data, the authors found little productivity growth based on this model (with the exception of Denmark, with 15.4% cumulated growth, and the United States, with about 5% from 1974 to 1989). The authors did find, however, that the highest productivity levels are found in the United States (Italy and Finland were also on the frontier of technology in the base period, 1974). The second model uses the same inputs as the first (but in per capita terms), but it specifies simple proxies of health outcomes as outputs: life expectancy of women at age 40 and the reciprocal of the infant mortality rate. CONCLUSIONS: For the 10 countries with complete data for this model, the authors found evidence of much more widespread and rapid productivity growth: Denmark's cumulated growth was close to 33%, with the United States close behind. In both these countries, this growth was due solely to technical change over this period.

Canada↗

Suicidal behavior in a bicultural society: a review of gender and cultural differences in adolescents and young persons of Aotearoa/New Zealand.

During the 1990s, Aotearoa/New Zealand has experienced an alarming increase in youth suicide in the Maori and non-Maori populations. Among 23 Organization for Economic Cooperation and Development countries surveyed by the World Health Organization's (1995) World Health Statistics Annual, New Zealand ranks first for fatal suicidal behavior, in males 15-24 years of age, and third for fatal suicidal behavior in females. A United Nations Children's Fund (UNICEF, 1996) survey of 32 countries places New Zealand males as third highest for fatal suicidal behavior, and females as eighth highest in the age group 15-24 years. New Zealand has recently undergone a number of social and economic changes that have created dramatic social and cultural shifts. Given the rapidity of these changes, the shock on such a small country has been difficult to absorb. These shifts have placed tremendous pressures on families and service support systems, such as health and mental health services, to develop programs that are relevant and acceptable for a bicultural society. This article focuses on these changes and the effect they have had on cultural narratives of gender and suicidal behavior, the different cultural etiologies that underlie these statistics, and recommendations for intervention and prevention program development.

Adolescent↗

Medical treatment and traffic fatality reductions in industrialized countries.

Reductions in traffic-related fatalities in developed industrialized countries have been substantial in the last 30 years. Most analyses have attributed this reduction to changes in vehicle design, better road design, increased seat-belt use, and reductions in driving under the influence of alcohol. This paper analyses the impact of improvements in medical treatment and technology. Data from the International Road and Traffic Accident Database (IRTAD), which includes all developed countries, was used in combination with Organization for Economic Cooperation and Development (OECD) Health Care data. Using proxy measures to account for improvements in medical treatment and technology it is found that these proxy variables are significant and capture much of the residual time trend in the data when they are omitted. Changes in age cohorts, such as fewer young people, also have contributed to a reduction in fatalities. These results suggest that medical technology improvements are associated with reductions in traffic-related fatalities over time.

Accidents, Traffic↗

The globalization of capital, the welfare state, and old age policy.

A new political economy is shaping the lives of present and future generations of older people. The key change has been the move from the mass institutions that defined growing old in the period from 1945 through the late 1970s to the more individualized structures--privatized pensions, privatized health and social care--that increasingly inform the current period. The authors examine the role of international governmental organizations in promoting this trend, with examples drawn from the work of the World Bank, World Trade Organization, and Organization for Economic Cooperation and Development, and the relationship between international governmental organizations and the state. The article concludes with an assessment of the changes to citizenship that accompany globalization and the implications for political organization among older people themselves.

Aged↗

What can the U.S. learn from national health accounting elsewhere?

The United States is typically seen as an outlier in health spending when compared with other advanced nations. Recent improvements in health accounting in lower- and middle-income countries suggest some common features with the high and pluralistic spending in the United States. The author discusses recent developments and findings in health accounting outside the Organization for Economic Cooperation and Development (OECD) and their relevance for the United States. He argues that we should expect more fruitful exchanges in the future.

Accounting↗

Inequalities in access to medical care by income in developed countries.

BACKGROUND: Most of the member countries of the Organization for Economic Cooperation and Development (OECD) aim to ensure equitable access to health care. This is often interpreted as requiring that care be available on the basis of need and not willingness or ability to pay. We sought to examine equity in physician utilization in 21 OECD countries for the year 2000. METHODS: Using data from national surveys or from the European Community Household Panel, we extracted the number of visits to a general practitioner or medical specialist over the previous 12 months. Visits were standardized for need differences using age, sex and reported health levels as proxies. We measured inequity in doctor utilization by income using concentration indices of the need-standardized use. RESULTS: We found inequity in physician utilization favouring patients who are better off in about half of the OECD countries studied. The degree of pro-rich inequity in doctor use is highest in the United States and Mexico, followed by Finland, Portugal and Sweden. In most countries, we found no evidence of inequity in the distribution of general practitioner visits across income groups, and where it does occur, it often indicates a pro-poor distribution. However, in all countries for which data are available, after controlling for need differences, people with higher incomes are significantly more likely to see a specialist than people with lower incomes and, in most countries, also more frequently. Pro-rich inequity is especially large in Portugal, Finland and Ireland. INTERPRETATION: Although in most OECD countries general practitioner care is distributed fairly equally and is often even pro-poor, the very pro-rich distribution of specialist care tends to make total doctor utilization somewhat pro-rich. This phenomenon appears to be universal, but it is reinforced when private insurance or private care options are offered.

Adolescent↗

The influence of the sulphonic group on the biodegradability of n-alkylbenzene sulphonates.

1. Model compounds of the type p-n-alkylbenzene sulphonates, p-n-alkylbenzoic acids and phenylcarboxylic acids were tested for biodegradability. Bioassays were performed with unadapted mixed cultures (soil suspensions) using the Organization for Economic Cooperation and Development (OECD) screening test. 2. Degradation was measured by dissolved organic carbon analysis and g.l.c. or h.p.l.c. 3. p-n-Alkylbenzene sulphonates were resistant to microbial attack. The carboxylated compounds with analogous structures, however, with one exception, were easily decomposed. 4. The results indicate that the persistent character of p-n-alkylbenzene sulphonates is mainly due to the sulphonic substituent.

Bacteria↗

Road traffic accidents in Nigeria: a review and a reappraisal.

Based on data that are at best conservative estimates, Nigeria is a country with a serious and growing road accident problem that is about the worst in the world. As can be seen from the trend over a 15-year period (1971-1985), legislative and other countermeasures thus far have proved ineffective. In 1988, a new approach was adopted with the formation of a national body charged with road traffic accident control--The Federal Road Safety Commission. In this paper, the programme of action of this body is examined to see to what extent it hopes to be able to fulfil its mandate. Suggestions are made on how the motorized industrialised countries can give assistance to developing countries through such bodies as the World Health Organization (WHO), the Organization for Economic Cooperation and Development (OECD), and the World Bank.

Accident Prevention↗

National health system steps in Turkey: concerns of family physician residents in Turkey regarding the proposed national family physician system.

Many countries are currently struggling with the public desire for improved health care and provision of basic services on the one hand, and the rising costs of health care on the other. Turkey is acutely experiencing this problem because of its relatively advanced level of economic development and its relatively low level of health status compared to Organization for Economic Cooperation and Development and European Union countries. Since 1990, there has been vigorous debate in the Turkish society regarding the best way to improve public health through improved primary health care. The current government is pursuing a proposal that has been mentioned before, but in a more serious effort than has been previously made. This is an approach to primary care based on systems such as those in the United Kingdom and in Germany, and the basic components are family physicians who have a particular list of patients whom they provide care for. Financing of the system is to be provided with a new general health insurance scheme. In this study, 38 family practice residents at the 3 major training hospitals for this specialty completed an investigator-designed questionnaire for the purpose of characterizing their concerns regarding this proposed system of primary health care delivery. The participants' responses indicated that the new system, which is known as the Family Physician System, will contribute importantly toward raising the overall level of health in Turkey. Specific expected benefits include closer patient-physician relationships, increased job satisfaction on the part of family physicians, and an overall increase in income for the physicians working in the system.

Adult↗

Impacts of informal caregiver availability on long-term care expenditures in OECD countries.

OBJECTIVE: To quantify the effects of informal caregiver availability and public funding on formal long-term care (LTC) expenditures in developed countries. DATA SOURCE/STUDY SETTING: Secondary data were acquired for 15 Organization for Economic Cooperation and Development (OECD) countries from 1970 to 2000. STUDY DESIGN: Secondary data analysis, applying fixed- and random-effects models to time-series cross-sectional data. Outcome variables are inpatient or home heath LTC expenditures. Key explanatory variables are measures of the availability of informal caregivers, generosity in public funding for formal LTC, and the proportion of the elderly population in the total population. DATA COLLECTION/EXTRACTION METHOD: Aggregated macro data were obtained from OECD Health Data, United Nations Demographic Yearbooks, and U.S. Census Bureau International Data Base. PRINCIPAL FINDINGS: Most of the 15 OECD countries experienced growth in LTC expenditures over the study period. The availability of a spouse caregiver, measured by male-to-female ratio among the elderly, is associated with a $28,840 (1995 U.S. dollars) annual reduction in formal LTC expenditure per additional elderly male. Availability of an adult child caregiver, measured by female labor force participation and full-time/part-time status shift, is associated with a reduction of $310 to $3,830 in LTC expenditures. These impacts on LTC expenditure vary across countries and across time within a country. CONCLUSIONS: The availability of an informal caregiver, particularly a spouse caregiver, is among the most important factors explaining variation in LTC expenditure growth. Long-term care policies should take into account behavioral responses: decreased public funding in LTC may lead working women to leave the labor force to provide more informal care.

Adult↗

Genetic testing: policy issues for the new millennium.

The purpose of this article is to provide a brief overview of the policy considerations underlying the Organization for Economic Cooperation and Development (OECD) workshop, "Genetic Testing: Policy Issues for the New Millennium," which was organised and hosted by the governments of the United Kingdom (UK) and Austria in Vienna, 23-25 February 2000, with the support of the European Commission (EC). It reviews the various topics presented at the meeting and offers a brief summary of its main conclusions.

Biotechnology↗

[Evolution of air pollution and impact on control programs in 3 megacities in Latin America].

The present work discusses the problems of atmospheric pollution of three Megacities of Latin America (Mexico City, Sao Paulo and Santiago). The environmental pollution control programs implemented by the Government are revised and the evolution of pollution levels during the period of 1988-1995 at Santiago de Chile and Sao Paulo, but until 1997 at Mexico City, in order to evaluate the impact of these programs. During this period, a decreasing trend is observed in the three cities in the levels of PTS, PM10, SO2, NO2, CO and O3, although most of these contaminants still exceed the air quality standards. It must be emphasized that the largest impact has been on the levels of SO2. We recommend the development of sustainable transport policies; in this context, various strategies were proposed by the Organization for Economic Cooperation and Development (OECD) in the European Conference of Ministers of Transport. Additionally, public participation is important when decisions are taken on transport policies.

Air Pollution↗

Utility of a juvenile fathead minnow screening assay for detecting (anti-)estrogenic substances.

The European Chemical Industry's aquatic research program for endocrine disrupters includes the development of an in vivo juvenile fathead minnow (Pimephales promelas) screening assay. Working within the Organization for Economic Cooperation and Development's (OECD, Paris, France) tiered approach to endocrine disrupter evaluation in fish, the juvenile fish screening protocol was adapted from the OECD test guideline 204. Six chemicals, with different (anti-)estrogenic potencies, were used to develop the in vivo juvenile fish screening protocol: diethylstilbestrol, 17alpha-ethynylestradiol, genistein, methoxychlor, 4-tert-pentylphenol, and ZM189,154 (a novel pharmaceutical antiestrogen). Mixed-sex juvenile fathead minnows were exposed to individual chemicals (with chemical analyzes) and sampled after 4, 7, 14, and 21 d of exposure. Wet weight, total length, condition factor, and whole-body homogenate concentrations of vitellogenin (VTG) were determined. Estrogens and antiestrogens were detected in this screen by virtue of the VTG response (an elevation or suppression, respectively) after 14 d. The study showed that the use of VTG concentrations in mixed-sex juvenile fish provides a sensitive and robust assay for the detection of both estrogenic and antiestrogenic chemicals, with widely divergent potencies.

Animals↗

Assessment of in vivo assays for endocrine disruption.

The United States Environmental Protection Agency (USEPA) has developed a screening and testing programme to detect endocrine-disrupting chemicals. This programme is organized into two phases: a tier 1 screening battery and, for those chemicals that are positive in this phase, a tier 2 testing battery. Similarly, the Organization for Economic Cooperation and Development (OECD) has set up a task force to identify, prioritize and validate test methods for the detection of endocrine disrupters. This chapter describes the mammalian in vivo assays recommended by these organizations. The tier 1 screening recommended by both agencies comprises the uterotrophic assay for the detection of oestrogens and anti-oestrogens, and the Hershberger assay for the detection of anti-androgens. Both of these assays are nearing the end of a comprehensive validation process and show consistency across testing laboratories. A further assay recommended by the USEPA is the female pubertal assay, designed to assess steroidogenesis, anti-thyroid activity and anti-oestrogenicity, while the OECD recommends an enhanced version of their standard regulatory test guideline number 407, the 28-day rat toxicity test. The tier 2 test recommended by both agencies is an enhanced version of the two-generation regulatory study. This is a large time- and animal-consuming study, and in order to obtain the maximum information regarding the potential for endocrine-disrupting activity of a chemical, it should be modified depending on the results of the tier 1 assays.

Androgen Antagonists↗

Potency grading in carcinogen classification.

In 1992 the United Nations Conference on Environment and Development decided to harmonize carcinogen classification systems. A proposal for a harmonized classification system is currently being considered by the Organization for Economic Cooperation and Development (OECD). In many countries, classification of a chemical as carcinogenic triggers labeling requirements. Implicit in the labeling requirements are often restrictions on the sale of consumer products and workplace regulations. Many of the current classification systems for carcinogens use a single concentration limit for the minimum concentration of a carcinogen in a preparation (mixture) that requires labeling. For high-potency carcinogens, one concentration limit may not adequately express the hazard, whereas for low-potency carcinogens, one limit may overestimate the hazard caused by the carcinogen in the preparation (mixture). The potency grading system discussed consists of three potency groups: high-, medium-, and low-potency carcinogens. It is envisioned that the different classes will trigger different labeling requirements. In the process of potency grading, a preliminary conclusion as to whether a substance shows high, medium, or low potency is initially based on a tumorigenic dose descriptor. The preliminary potency evaluation may then be modified after due consideration of a number of additional elements. These may include evaluation of the dose-response curve; site-, species-, strain-, and sex-specific activity; mechanisms including genotoxicity; mechanistic relevance to humans; toxicokinetics; and other factors. The potency grading system discussed is applicable to most carcinogen classification systems, including that currently being considered by the OECD.

Animals↗

Beyond the initial indicators: lessons from the OECD Health Care Quality Indicators Project and the US National Healthcare Quality Report.

UNLABELLED: Interest in comparative quality measurement and evaluation has grown considerably over the past two decades because of factors such as the recognition of widespread variation in clinical practice, the increased availability of evidence about medical effectiveness, and increasing concern about the cost and quality of health care. This article describes and contrasts two current efforts to develop health performance reporting systems: one, an international initiative-the Health Care Quality Indicator (HCQI) Project, sponsored by the Organization for Economic Cooperation and Development (OECD); and the other, a national project-the National Healthcare Quality Report (NHQR), sponsored by the US Agency for Healthcare Quality and Research. There are a number of lessons learned from a comparison of the two efforts that are relevant for the future of each project and for other indicator-based reporting efforts in quality of health care. These lessons are discussed in the article and include: Conceptual frameworks should be established to guide the selection of indicators. Choices should be made early on in the process to focus on a wide range of clinical conditions or to report on a few priority areas. METHODS: should be developed to add and subtract indicators while maintaining a stable set of indicators to track over time. Resources should be allocated to communication strategies and how best to present data results to diverse audiences. Mechanisms should be put in place to maintain project momentum.

Benchmarking↗

Economic expansion is a major determinant of physician supply and utilization.

OBJECTIVE: To assess the relationship between levels of economic development and the supply and utilization of physicians. DATA SOURCES: Data were obtained from the American Medical Association, American Osteopathic Assocation, Organization for Economic Cooperation and Development (OECD), Bureau of Health Professions, Bureau of Labor Statistics, Bureau of Economic Analysis, Census Bureau, Health Care Financing Administration, and historical sources. STUDY DESIGN: Economic development, expressed as real per capita gross domestic product (GDP) or personal income, was correlated with per capita health care labor and physician supply within countries and states over periods of time spanning 25-70 years and across countries, states, and metropolitan statistical areas (MSAs) at multiple points in time over periods of up to 30 years. Longitudinal data were analyzed in four complementary ways: (1) simple univariate regressions; (2) regressions in which temporal trends were partialled out; (3) time series comparing percentage differences across segments of time; and (4) a bivariate Granger causality test. Cross-sectional data were assessed at multiple time points by means of univariate regression analyses. PRINCIPAL FINDINGS: Under each analytic scenario, physician supply correlated with differences in GDP or personal income. Longitudinal correlations were associated with temporal lags of approximately 5 years for health employment and 10 years for changes in physician supply. The magnitude of changes in per capita physician supply in the United States was equivalent to differences of approximately 0.75 percent for each 1.0 percent difference in GDP. The greatest effects of economic expansion were on the medical specialties, whereas the surgical and hospital-based specialties were affected to a lesser degree, and levels of economic expansion had little influence on family/general practice. CONCLUSIONS: Economic expansion has a strong, lagged relationship with changes in physician supply. This suggests that economic projections could serve as a gauge for projecting the future utilization of physician services.

Cross-Sectional Studies↗

Effects of bis(tri-n-butyltin)oxide in Japanese quail exposed during egg laying period: an interlaboratory comparison study.

The guideline no. 206 for testing of chemicals of the Organization for Economic Cooperation and Development (OECD) comprising an avian reproduction test using the Japanese quail (Coturnix coturnix japonica; Termminck and Schlegel 1849) as pair-hold test organisms has been applied in a version that reduced the treatment period to 6 weeks without any pretreatment. In the present study bis(tri-n-butyltin)oxide, C.A. No. 56-35-9 (tributyltin oxide, TBTO) was examined by five participants in an interlaboratory comparison test. A comparable regimen of dosing was performed by all participants starting either with 24 or 60 mg/kg TBTO in the feed and ending with 150 or 375 mg/kg. Within this dose range no signs of toxicity in adults were observed. Substance-related effects however were obvious with regard to egg production, fertility, hatching success, and survival of 14 day-old chicks. A clear dose dependency was given regarding effects on egg weight and on hatchability. The no-observed-effect concentrations for these two parameters was 60 mg/kg TBTO, characterizing these parameters as the most sensitive in this investigation. With the presented set of test parameters further aspects of subchronic toxicity in adults and chicks can be assessed as well as the validity of the performed test. Comparing the results for most test parameters consistency is obvious, thus confirming the applicability of the presented test guideline.

Animals↗