[That which aids better understanding of the pharmacognosy course].
Explore the source record for details and available documents.
SEARCH · PubMed Health
Explore indexed PubMed citations for clinical trials, systematic reviews and public health research. Read source abstracts and follow each citation to its original PubMed record.
Quote a phrase for an exact phrase match. Source license links do not imply unrestricted reuse.
Explore the source record for details and available documents.
Explore the source record for details and available documents.
Explore the source record for details and available documents.
Explore the source record for details and available documents.
Explore the source record for details and available documents.
Explore the source record for details and available documents.
Explore the source record for details and available documents.
Explore the source record for details and available documents.
Explore the source record for details and available documents.
Explore the source record for details and available documents.
Explore the source record for details and available documents.
Explore the source record for details and available documents.
Explore the source record for details and available documents.
1. Progress made in pharmacognostic research by Chinese investigators in the last decade is summarized herein. 2. This review covers studies on herbal properties, resources, identification, physicochemical evaluation, cultivation, breeding, tissue culture, collection, processing, preparation, active principles and pharmacological activities of traditional and herbal Chinese drugs. 3. As a result of these research activities errors in species identification were spotted, new drug resources were revealed, new taxa were discovered, crude drugs were analyzed qualitatively and quantitatively, optimal conditions for cultivation and breeding of plants and animals used as drugs were formulated, the quality of some drugs was controlled, the drug processing procedures and storage conditions were evaluated, and the chemistry and pharmacology of a number of crude drugs were elucidated.
A chemical investigation of the bark of Mimosa tenuiflora (Willd.) Poiret, performed in our laboratory, allowed the isolation and identification of three new triterpenoid saponins (mimonosides A, B and C), three steroid saponins (3-O-beta-D-glucopyranosyl campesterol, 3-O-beta-D-glucopyranosyl stigmasterol and 3-O-beta-D-glucopyranosyl beta-sitosterol) together with lupeol, campesterol, stigmasterol and beta-sitosterol. The three new triterpenoid saponins were subjected to in vitro biological tests (immunomodulation and proliferation) using different animal and human cells in culture. The results of these tests contribute to explain the traditional use of this plant material.
The more a critical look at the medicinal properties of plants is undertaken, the more it will be realized that nature does not make it easy to find all there is to know about them and the complexities of their interactions. An illustration of this can be found in one of the earlier scientific studies on phytomedicines, the Nobel laureate Albert Szent-Györgyi and his colleagues [170] found that flavanone extracts from the Capsicum spp contain an ascorbate-protective factor. It has now been repeatedly shown that the electron-donating properties of the phytochemical flavonoids, providing both nutritive and chemotherapeutic benefits, are the basis of their antioxidant action [171-175]. Studies by zoologists have demonstrated that animals, by selectively choosing specific plants, soils, and clays, maintain their health and treat themselves in times of ill health. The term zoopharmacognosy, now well researched, has been coined to describe the study of this recognized phenomenon. Long ago, Isaac Newton stated that for every action, there is an equal and opposite reaction. The same may be seen in plants and plant material. The same may be said of life in general. At the most basic concept, we are talking of electrons and their activities.
As the population ages, there is an ever-increasing need for therapeutic agents that can be used safely and efficaciously to manage symptoms related to postmenopausal estrogen deficiency. Endogenous estrogens, e.g., 17beta-estradiol, of exogenous mammalian origin, e.g., horses, have long been used to manage such symptoms. There are more than 20 different classes of phytochemicals that have demonstrated affinity for human estrogen receptors in vitro. Some studies on exogenous estrogenic substances of botanical origin (phytoestrogens), such as standardized formulations of plant extracts with in vitro and in vivo estrogenic activity from soy (Glycine max Merill.) and red clover (Trifolium pratense L.), suggest clinical efficacy. Few clinical data for phytoestrogens other than isoflavonoids are available. In an exhaustive review of the literature through 2003, only two clinical trials were identified that were designed to evaluate the effect of hops (Humulus lupulus L.) on symptoms related to menopause. Folkloric, chemical, and biological literature relating primarily to the use of hops for their estrogenic activity, and two human clinical trials, are reviewed.
Explore the source record for details and available documents.