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At least 37 records · Page 2Linked to original sources

SCL 90-R interpretation and brain tumour: a correction factor?

OBJECTIVE: Determine whether spurious SCL 90-R profiles resulting from endorsement of neurologic treatment items can be corrected and still retain ecological validity. DESIGN: The proportion of subjects' item endorsement was compared with the adult non-patient norm group. Items with discriminative power (chi 2 > 25, p < 0.001 and endorsement by at least 25% of subjects) underwent principal-components analysis with somatic treatment and psychiatric factors identified. Items in the somatic treatment factor were extracted as the corrective factor. The resultant corrected T scores were plotted against original SCL 90-R profiles. SETTING: University medical centre. PATIENTS: Thirty community dwelling adults with biopsy confirmed malignant brain tumours referred by their treating physician for evaluation prior to aggressive treatment. INTERVENTIONS: The SCL 90-R was part of a neuropsychological test battery. MAIN OUTCOME MEASURE: The SCL 90-R was selected prior to data collection because it is the second most frequently used psychosocial instrument in medical settings, yet has demonstrated attenuated validity with neurologic patients. RESULTS: Extraction of 10 somatic treatment items resulted in lower profiles on Somatization, OBSESSIVE: Compulsive, Depression, and Anxiety dimensions and the global indicators. However, clinical caseness for individuals remained greater than indicated by clinical interview. CONCLUSION: Correction for SCL 90-R neurologic treatment items resulted in reduced sensitivity and poorer ecological validity.

Adult↗

Encephalopathy associated with bismuth subgallate therapy.

A 74-year-old man developed paranoid ideation, memory impairment, and defective gustatory and olfactory function while on bismuth subgallate therapy for use as a colostomy deodorant. Twenty-four-hour urine bismuth was elevated at 889 micrograms/day, and whole blood bismuth concentration was 67 micrograms/L. The patient improved after discontinuation of bismuth subgallate; there was resolution of paranoid behavior and gustatory and olfactory functions improved. Follow-up whole blood bismuth concentration was 21 micrograms/L 4 weeks after cessation. Altered gustatory and olfactory function have not been previously reported with bismuth intoxication.

Aged↗

Behavioral disorders in the elderly.

Based on the study of 40 patients in a unit of a large geriatric center, as well as on long overall experience, the problems of aged men and women with various emotional disorders are discussed. Case abstracts are presented to illustrate chronic organic brain syndrome, delirium, hallucinatory behavior, paranoid ideation, depression, and reactions triggered by physical illness. The geriatrician should be fully aware of all the interlocking factors in the patient's adjustment to his condition. Only in this way can the geriatrician and staff choose the best relevant therapy.

Adjustment Disorders↗

Central nervous system depression associated with glucocorticoid ingestion in a dog.

Signs of a central nervous system disorder were observed following 2 instances of accidental ingestion of glucocorticoid in a young female Doberman Pinscher. The signs included transient aggressive and paranoid behavior, amaurosis, disorientation, ataxia with circling backward, and depression. Vomiting, weight loss, and abnormal drinking behavior persisted for several weeks following recovery from the acute illness.

Animals↗

Psychological testing at high altitudes.

Psychological testing was done on 20 subjects at various altitudes (sea level, 3,8,10 m, and 5,000 m) during a 35-d mountaineering expedition to Denali (Mt. McKinley). Intellectual functioning and personality changes were studied. While little variation was noted at the lower altitude, at 5,000 m there was a marked deterioration in cognitive ability. This was accompanied by a sharp increase in paranoia and obsessive-compulsiveness and smaller increases in depression and hostility.

Adolescent↗

[Medical-psychologic study of somatic patients].

An attitude towards the disease in patients with chronic somatic disturbances is determined by three factors: the nature of the disease, personality type and the attitude to this particular disease in the microsocial environment to which the patient belongs. Three main types of attitudes towards their disease in patients with chronic somatic disturbances are described: anxious-depressive, melancholic, obsessive-phobic, hypochondriacal, neurasthenical, dysphoric, euphoric, anozognosic, apathetic, egopathic (a fanatic preoccupation with work), sensitive, egocentric, paranoiac. These types may be mixed as well. A knowledge of the above-mentioned types is useful for psychotherapeutic approaches.

Adolescent↗

Paranoid and aggressive behavior in two obsessive-compulsive adolescents treated with clomipramine.

Obsessive-compulsive disorder is increasingly recognized in patients of different age groups. Serotonergic agents, such as clomipramine, have been recently found to be useful in the management of this condition. However, unexpected side effects, such as dysphoria, aggressiveness, and paranoid ideation, may occur with therapeutic doses of this compound, as evidenced in the cases of two male adolescents presented here. Possible pathogenetic factors, involving serotonin and serotonin-receptor abnormalities are discussed. Management of these side effects is based on adequate dose reduction and monitorization.

Adolescent↗

[Psychoses and unidentified flying objects].

Some individuals claim to have come into contact and communicated with occupants of flying objects of extraterrestrial origin who often would have entrusted them with "missions" regarding the safeguard of humanity. The authors, who have observed six such subjects, conclude that five of them suffered from a paranoid delusional state often akin to paraphrenia; whereas other analogous cases previously reported have been diagnosed as suffering from paranoid schizophrenia. Their beliefs, inaccessible to criticism and to reasoning, presumably help them to remain outside psychiatric reach. The present article does not take an interest in the physical existence of this phenomenon and does not wish to be reductionistic. It does not claim to express a judgment on the witnesses of such phenomena whose mental health must be evaluated through a rigorous and impartial examination, and not be evaluated in terms of the examiner's preconceptions toward the witnesses' assertions.

Delusions↗

Ethological study of facial behavior in nonparanoid and paranoid schizophrenic patients.

This investigation addressed the question of affective disturbance in schizophrenia by applying quantitative measurement techniques to patients' facial behavior. The subjects were medication-free male inpatients: nine nonparanoid and six paranoid schizophrenic patients and 12 drug- or alcohol-abuse rehabilitation control patients. Two judges scored the subjects' behavior, which was recorded on videotape, according to a system that included 16 different types of facial movements. Eye blinks, eye contact, and words spoken were also scored. Compared to the control patients, the nonparanoid schizophrenic patients spoke significantly fewer words and had significantly less eye contact, while the paranoid schizophrenic patients had significantly fewer eyebrow and lower facial movements.

Adult↗

Death in Jonestown: techniques of political control by a paranoid leader.

Jim Jones and Jonestown are discussed from a "political control" point of view. Seven basic techniques of political control are identified: Control of property and income, weakening of family ties, a sociopolitical caste system, control of egression (escape), control of verbal expression, cognitive control and emotional control. Jonestown is identified as a mini-totalitarian state ruled by a delusional and paranoid person.

Famous Persons↗