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PubMed2000

Preparing children for surgery--an integrative research review.

The purpose of this integrative research review was to determine the methodological and substantive characteristics of the research pertaining to preparation of children for surgery, examine pertinent research issues, and suggest recommendations for future research and practice. A total of 400 articles were reviewed using inclusion and exclusion criteria. Twenty-two studies, published between 1974 and 1995, met the criteria and, therefore, constituted the study corpus. The total sample comprised 1,263 subjects. Findings indicate that further research is needed to examine the efficacy of preparation strategies, address diverse populations, and include patient and parent involvement in the preparation process.

Adolescent↗
PubMed2005

Teaching research integrity and bioethics to science undergraduates.

Undergraduate students in the Department of Biomedical Sciences at the University of South Alabama, Mobile, are required to take a course entitled "Issues in Biomedical Sciences," designed to increase students' awareness about bioethical questions and issues concerning research integrity. This paper describes the main features of this course and summarizes the results of a survey designed to evaluate the students' perceptions about the course. A summary of this study was presented at the 2002 Conference on Research Integrity in Potomac, MD, sponsored by the Office of Research Integrity of the National Institutes of Health.

Bioethics↗
PubMed2003

Promoting research integrity at the American Society for Microbiology.

The American Society for Microbiology addresses issues of research integrity in several ways. There is a Code of Ethics for Society members and an Ethics Committee, a Publications Board has editorial oversight of ethical issues involved in Society journals and other publications, and the Public and Scientific Affairs Board is involved in ethical issues and scientific policies at the national level. In addition, the Society uses meetings and publications to inform and educate members about research integrity.

Codes of Ethics↗
PubMed2006

Complainant issues in research misconduct: the office of research integrity experience.

This paper discusses the experiences of the Office of Research Integrity (ORI) with issues involving complainants who make allegations of research misconduct. The paper describes the legal framework for complainant issues, the various roles of the complainant as the allegation of misconduct proceeds through the steps of investigation and resolution, how allegations of retaliation against the complainant are handled, the responsibilities of ORI and of the research institution where the alleged misconduct occurred, and ORI's experience with several cases of alleged retaliation. In each of these areas, the paper attempts to provide guidance to prospective complainants, research institutions, and other interested persons on effective ways to approach the various problems and concerns that arise, while maintaining a balance between the needs of the complainant, the accused, the research institution handling the allegation, and ORI.

Academies and Institutes↗
PubMed2003

Scientific societies and research integrity: what are they doing and how well are they doing it?

Scientific societies can play an important role in promoting ethical research practices among their members, and over the past two decades several studies have addressed how societies perform this role. This survey continues this research by examining current efforts by scientific societies to promote research integrity among their members. The data indicate that although many of the societies are working to promote research integrity through ethics codes and activities, they lack rigorous assessment methods to determine the effectiveness of their efforts.

Ethics, Research↗
PubMed2004

Integrating research and practice in the CSAT Methamphetamine Treatment Project.

This study investigates the dynamics of integrating research and practice in community-based treatment organizations that participated in the Center for Substance Abuse Treatment Methamphetamine Treatment Project (MTP). Qualitative, semi-structured interviews were conducted in eight treatment organizations throughout the western United States and involved 85 participants working either directly under the MTP cooperative agreement (n = 77) or for the agency in which the MTP was taking place (n = 8). The interview explored how participants viewed the integration of substance abuse treatment and research and how they characterized successful and ideal drug treatment. Participants were concerned that clients' needs were not met within the parameters of a research study. They also described new relationships (e.g., between Research Assistants and clients) that had potentially important implications for the integrity of research in clinical settings. Projects attempting to integrate research and practice should attend to clinicians' orientations toward clients and to the effects of research on treatment program dynamics.

Adult↗
PubMed1999

Office of Research Integrity: a reflection of disputes and misunderstandings.

Each year, the U.S. Public Health Service (PHS) provides billions of dollars to support over 30,000 extramural research grants to more than 2,000 institutions in the U.S. and other countries. The Office of Research Integrity (ORI) is responsible for protecting the integrity of the research supported by the grants awarded for the PHS extramural research program. One of its responsibilities includes monitoring investigations into alleged or suspected scientific misconduct by institutions that receive the PHS funds. However, not all of the alleged or suspected scientific misconduct meet the the PHS definition of scientific misconduct. Among the wide range of allegations that the ORI receives are those that are ultimately determined to be authorship disputes. This article will report on ORI's functions and review some of the commonly reported allegations that do not constitute scientific misconduct according to the PHS definition.

Authorship↗
PubMed2002

Participatory action research: integrating community occupational therapy practice and research.

Participatory action research (PAR) is a form of collaborative research particularly concerned with power inequities of marginalized communities. With this approach, occupational therapists can work with clients and communities to address issues of access, inclusion, equity and collaboration in practice and research. This paper begins with a summary of key concepts and controversies related to participatory action research. Two examples from occupational therapy experience are used to demonstrate the initial steps and key principles of PAR projects and to highlight the conceptual links between PAR and community-based, client-centred occupational therapy. One project involved a group of mental health consumers, the other a community group of older adults. Several challenges and potential outcomes in PAR projects are highlighted in this examination of the complexity of PAR processes. The paper concludes by identifying possibilities and obstacles to the further use of PAR in occupational therapy.

Aged↗
PubMed2003

Trapping and marking terrestrial mammals for research: integrating ethics, performance criteria, techniques, and common sense.

We propose that researchers integrate ethics, performance criteria, techniques, and common sense when developing research trapping programs and in which members of institutional animal care and use committees address these topics when evaluating research protocols. To ask questions about ethics is in the best tradition of science, and researchers must be familiar with codes of ethics and guidelines for research published by professional societies. Researchers should always work to improve research methods and to decrease the effects on research animals, if for no other reason than to minimize the chances that the methods influence the animals' behavior in ways that affect research results. Traps used in research should meet performance criteria that address state-of-the-art trapping technology and that optimize animal welfare conditions within the context of the research. The proposal includes the following criteria for traps used in research: As Criterion I, killing-traps should render >/= 70% of animals caught irreversibly unconscious in </= 3 min (calculated with 95% confidence). As Criterion II, live-traps should trap >/= 70% of animals with </= 50 points scored for physical injury (calculated with 95% confidence). The types of traps described include killing-traps (snap traps, rotating jaw traps, snares, pitfalls, and drowning sets), common sets, and the common types of live-traps (box and cage traps, pitfalls, foothold traps. snares, corrals and nets, and dart collars). Also described are trapping methods for specific mammals, according to which traps fulfill Criteria I and II for which species, and techniques for short-term, long-term, and permanent marking of mammals.

Animal Experimentation↗
PubMed1998

Anonymity and pseudonymity in whistleblowing to the U.S. Office of Research Integrity.

Given the concerns expressed by members of the academic and legal community about whether (and how) to handle anonymous and pseudonymous allegations of scientific misconduct, this paper summaries the experiences of the Office of Research Integrity and its predecessor from 1989 through 1997. Although the record shows that research institutions and the ORI have treated such allegations seriously, the fraction of complainants to the ORI who remain anonymous is small (8% of 986 allegations); few anonymous complaints are sufficiently substantive to be pursued (4% of the 357 formal cases opened in the ORI); and only 1 of these 13 cases resulted in an ORI finding of scientific misconduct.

Anonyms and Pseudonyms↗
PubMed2004

Integrating research on temperament and childhood psychopathology: its pitfalls and promise.

This article discusses the promise and problems associated with integrating research on child temperament and research on childhood psychopathology. Unfortunately, these 2 extensive and influential areas of psychological research with children have largely been conducted independently of each other. This article provides a summary of the disciplinary, conceptual, and methodological issues that have hampered an integration of these 2 important bodies of research. It also highlights the great promise that such an integration could have for advancing causal theories of childhood disorders and for eventually improving the treatment provided to children with serious emotional and behavioral disturbances.

Adolescent↗
PubMed2002

[Problems integrating research projects in routine medical practise].

Better integration of research projects into the rheumatologic private practises in Germany is of great interest both for the scientific project carriers and for the rheumatologists in practice themselves. The present restrictions in this area may be explained by the lack of resources of this group of rheumatologists needed for such an engagement, mainly for economic reasons. There would be the need to integrate surgery reserach into the practices, with sufficient additional space and man power. For this goal, the material and legal conditions would have to be created.

Biomedical Research↗
PubMed2005

Authors' reports about research integrity problems in clinical trials.

BACKGROUND: There is little information about the prevalence of research integrity problems in the scientific literature. We sought to determine how frequently authors of published pharmaceutical clinical trials reported fabrication of data or misrepresentation of research. METHODS: We conducted a mail survey of 549 authors who had published reports of pharmaceutical clinical trials from 1998 to 2001 that appeared in the Cochrane Database of Systematic Reviews. We asked authors about fabricated data or misrepresentations of research in three contexts: the target study (the report from which their name was obtained), another study they had participated in, or a study that they personally knew about. RESULTS: We received replies from 64% of authors with valid addresses. Two authors (1%) reported that the target article misrepresented the research. Almost 5% reported fabrication or misrepresentation in a study they had participated in the last 10 years, and 17% of authors personally know about a case of fabrication or misrepresentation in the last 10 years from a source other than published accounts of research misconduct. CONCLUSIONS: Fraud and misrepresentation in clinical trials appear to be rare on a per-published report basis. However, they occur sufficiently frequently that scientists have a significant chance of participating in a project affected by fraud or misrepresentation during their research careers. These rates of exposure justify vigorous efforts to prevent research misconduct.

Adult↗