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Phacoemulsification and retinal detachment.

Retinal detachment is not eliminated nor decreased to a rare complication after phacoemulsification. There were 94 eyes examined with retinal detachments after phacoemulsification and the majority were operated upon. The fundus view might be hampered and some areas of the retina obscured by this form of lens extraction. There are, however, some cases where the small incision and relative clarity of the media, soon after cataract surgery, offer an advantage.

Adolescent↗

Latest developments in treating retinal detachment.

Retinal detachment is a significant cause of blindness. Until the second quarter of this century, no successful treatment was available. Since then, there have been many exciting developments so that nowadays the majority of retinal detachments can be successfully repaired.

Cryosurgery↗

[Retinal detachment].

Retinal detachment is a rare but serious disease with potential socio-professional repercussions. Its prevention rests on information of medical practitioners and patients and on photocoagulation with argon laser. Nowadays, the curative treatment of retinal detachment is surgical. When applied at an early stage and correctly performed, it should normally give satisfactory functional results.

Humans↗

[Retinal detachments and retinal surgery].

The incidence of retinal detachment is approximately 1:10,000. Most retinal detachments occur between the ages of 50 and 65 years. A rhegmatogenous retinal detachment starts with a tear in the peripheral retina. Through this retinal tear liquefied vitreous may enter the subretinal space, resulting in a retinal detachment with progressive visual loss. In 50% prodromal light flashes are observed. Laser coagulation around a tear without subretinal fluid can make surgical intervention unnecessary in approximately 96% of cases. When subretinal fluid is present, conventional scleral buckling surgery is successful in 80-90% of the cases. In more complex retinal detachments or in re-detachment cases, a trans pars plana vitrectomy is indicated. Anatomical success can be achieved in approximately 96% of cases, sometimes after several operations. Functional success depends on preoperative pathology and duration of the detachment. Eyes with retinal detachment of the macula and with larger and complex defects have poorer visual prognosis.

Aged↗

Effects of laser wavelengths on experimental retinal detachments and retinal vessels.

We studied the effects of the yellow (577 nm), orange (595 nm) and red (630 nm) dye lasers, the argon blue-green (488, 514.5 nm) and green (514.5 nm) lasers, and the krypton red (647 nm) laser on experimentally produced serous and hemorrhagic retinal detachments and on retinal vessels in rabbits. Retinal detachments were created by either injecting balanced saline solution or partially hemolyzed blood under the retina. All laser wavelengths except the argon blue-green bypassed the sensory retina and produced no damage on either the sensory retina or the underlying retinal pigment epithelium with serous retinal detachment. Each laser wavelength, however, produced a specific effect on the detached retina with hemorrhagic fluid. Blue-green, green, yellow and orange wavelengths damaged the sensory retina more severely than the red wavelengths. Laser coagulation of the retinal vessels with the blue-green, green and orange wavelengths produced vasospasms.

Animals↗

Vitrectomy techniques in late-stage Coats'-like exudative retinal detachment.

Retinal telangiectasia is the hallmark of Coats' disease. In the late stages, leakage from these abnormal vessels can result in a total, bullous exudative retinal detachment with cholesterol-laden subretinal fluid. Secondary angle-closure glaucoma may result in a blind and painful eye which may require enucleation or evisceration. Surgical reattachment of the retina and destruction of the retinal telangiectasia may preserve these eyes. We have found that vitrectomy, internal drainage of subretinal fluid and cholesterol, direct treatment of the retinal telangiectasia with intraocular diathermy and intravitreal gas or silicone oil injection are effective surgical techniques for salvaging these severely damaged eyes.

Adult↗

Congenital myopia and retinal detachment.

Retinal detachment is unusual in children and is often associated with other serious ocular abnormalities. In more than 25 children varying in age from 3 to 16 years in whom the common ocular complication was congenital myopia, associated features included facial abnormalities and other changes often associated with familial and inherited conditions. A very high incidence of giant retinal breaks was found and these were associated with considerable difficulty in treatment.

Adolescent↗

Cellular remodeling in mammalian retina: results from studies of experimental retinal detachment.

Retinal detachment, the separation of the neural retina from the retinal pigmented epithelium, starts a cascade of events that results in cellular changes throughout the retina. While the degeneration of the light sensitive photoreceptor outer segments is clearly an important event, there are many other cellular changes that have the potential to significantly effect the return of vision after successful reattachment. Using animal models of detachment and reattachment we have identified many cellular changes that result in significant remodeling of the retinal tissue. These changes range from the retraction of axons by rod photoreceptors to the growth of neurites into the subretinal space and vitreous by horizontal and ganglion cells. Some neurite outgrowths, as in the case of rod bipolar cells, appear to be directed towards their normal presynaptic target. Horizontal cells may produce some directed neurites as well as extensive outgrowths that have no apparent target. A subset of reactive ganglion cells all fall into the latter category. Muller cells, the radial glia of the retina, undergo numerous changes ranging from proliferation to a wholesale structural reorganization as they grow into the subretinal space (after detachment) or vitreous after reattachment. In a few cases have we been able to identify molecular changes that correlate with the structural remodeling. Similar changes to those observed in the animal models have now been observed in human tissue samples, leading us to conclude that this research may help us understand the imperfect return of vision occurring after successful reattachment surgery. The mammalian retina clearly has a vast repertoire of cellular responses to injury, understanding these may help us improve upon current therapies or devise new therapies for blinding conditions.

Animals↗

Retinal detachment and retinal holes in retinitis pigmentosa sine pigmento.

Retinal detachment and retinal holes in two family members with retinitis pigmentosa sine pigmento are reported. We believe these are the first such cases reported in the literature. We describe the presenting symptoms and management, including cryotherapy, scleral buckling procedure, and sulfur hexafluoride injection (SF6), resulting in stable visual acuity in one case and retinal reattachment and improved visual acuity in the other case.

Adult↗

Surgery for retinal detachment.

Retinal detachment surgery in human patients is currently 90% successful, with most detachments amenable to treatment by scleral buckling procedures. The main obstacle to achieving comparable results in veterinary patients is the active nature of our patients during the postoperative convalescent period. Adapting current techniques to include short-term chorioretinal adhesion by way of tacking, cyanoacrylate adhesives, or other methods has shown substantial promise and should be further investigated in veterinary species. The technology and methods are currently available to produce success rates comparable to those achieved in human patients, and the near future promises to bring further refinements in veterinary applications.

Animals↗

Ciliary detachment after retinal detachment surgery.

PURPOSE: To evaluate the changes in the ciliary body and anterior choroid that occur after retinal detachment surgery. METHODS: Thirty-three eyes with rhegmatogenous retinal detachment were evaluated before and after surgery. An ultrasound biomicroscope was used to observe the ciliary body and anterior choroid. RESULTS: Ciliary detachment was found to be present in 22 eyes (67%) on examination 5-14 days after surgery. The detachment was confined to the pars plana in nine eyes and involved the pars plicata and plana in 13 eyes. The whole circumference of the ciliary body was detached in seven of the 13 eyes. In three of these seven eyes, ophthalmoscopy showed the detachment to extend to the anterior choroid. Ciliary detachment lasted for at least 2 weeks and resolved within 2 months in 19 of 22 eyes. A shallow anterior chamber was observed after surgery in 12 eyes with severe ciliary detachment. Ciliary detachment was more likely to occur in eyes with a large retinal tear, large area of scleral buckling, or in eyes that were treated with solid silicone exoplant. CONCLUSION: Ciliary detachment occurred frequently after retinal detachment surgery using scleral buckling. It was temporary and usually did not result in untoward complications.

Adolescent↗

Rhegmatogenous retinal detachment with retinal telangiectasia.

A 34-year-old man with unilateral retinal telangiectasia developed a bullous retinal detachment. A horseshoe retinal tear was found at 12 o'clock. The detachment resolved with placement of an encircling scleral buckle. The prompt and permanent resolution of subretinal fluid supported our belief that this was a rhegmatogenous retinal detachment.

Adult↗

Giant retinal tears, retinal detachment and retinitis pigmentosa.

A patient with retinitis pigmentosa and sensorineural deafness presented with bilateral giant retinal tears and a unilateral retinal detachment. The peripheral visual field loss could have been erroneously ascribed to the primary retinal dystrophy. A retinal detachment must be considered in patients with a sudden loss of visual acuity or field even if they have a primary retinal dystrophy.

Adolescent↗

Serous choroidal detachment after retinal detachment surgery.

In a prospective evaluation of 154 consecutive retinal detachment procedures, the incidence of choroidal detachment was 39.6%. The age of the patient, drainage of subretinal fluid, and vortex compression by the explant seem to be the most important correlative factors. Scleral explants up to one quadrant in circumferential length produced a minimal incidence (7.7%) of choroidal detachment. Posterior positioning of the explant also affected the incidence of choroidal detachment. After follow-up, ranging from six to 48 months, postoperative visual acuity was recorded for "macula-on" as well as "macula-off" retinal detachments. In the macula-on group, 78.6% of the patients with choroidal detachment retained a visual acuity of 20/50 or better compared with 82.8% of the patients without choroidal detachment. In the macula-off group, 43.2% of the patients with choroidal detachment achieved a visual acuity of 20/50 or better compared with 55.1% of the patients without choroidal detachment. The final anatomic success rate was 86.5% for eyes with choroidal detachment and 92.3% for eyes without choroidal detachment.

Age Factors↗

Peripheral retinal detachments and retinal pigment epithelial atrophic tracts secondary to central serous pigment epitheliopathy.

Twenty-five patients with central serous pigment epitheliopathy (CSP), also known as central serous chorioretinopathy, have been observed to have inferior hemispheric retinal pigment epithelial atrophic tracts, presumptive of antecedent retinal detachments. Five of these patients were noted to have clinically discernible, dependent peripheral retinal detachments. The clinical and fluorescein angiographic features of these patients are reviewed. Alterations in the retina, the retinal pigment epithelium (RPE) and the choroid are also described. They include the commonly associated manifestations of CSP such as RPE leaks and macular detachment as well as some newly recognized disturbances such as retinal capillary dilatation (telangiectasia), retinal capillary leakage, retinal lipid deposition, cystoid macular edema, choriocapillaris atrophy, choroidal neovascularization and disciform scarring.

Adult↗

[Incidence of lack of posterior vitreous detachment in retinal detachment caused by flap tear in the elderly].

I investigated whether posterior vitreous detachment is invariably associated with retinal detachment in the elderly caused by flap retinal tears. Of 97 eyes which underwent vitrectomy, Weiss' ring was not observed in 10 eyes during both the preoperative slit lamp microscope examination and the intraoperative surgical microscope observation. I proved by surgically detaching the posterior vitreous in 5 out of those 10 eyes that the posterior vitreous had not yet become detached before the operation. My results suggest that posterior vitreous detachment may not be associated with 5 to 10% of cases of retinal detachment caused by flap retinal tears.

Aged↗

[Visual acuity and binocular vision following surgery of extreme retinal detachment].

Retinal surgery with implantation of silicone oil was performed in 33 patients presenting with idiopathic or traumatic proliferative vitreoretinopathy. Following removal of the oil patients were on average followed-up for 6 to 29 months (14 months). Sixteen patients had had buckling procedures prior to endosurgery. Improvement of vision up to 4 rows of optotypes was noted in 21 patients following silicone oil removal. Three cases showed a large, organic, central scotoma. Ten patients suffered from diplopia; 3 of whom were known to have had a preexisting strabismus. Suppression of the visual impression of the operated eye was seen in 4 cases. Eye muscle surgery was necessary in 4 cases. Sixteen patients demonstrated normal binocular vision as far as possible taking the visual acuity into account.

Adolescent↗

Retinal detachment in retinitis pigmentosa.

Three cases of retinal detachment occurring in patients with retinitis pigmentosa are presented and three previously reported cases reviewed. All the detachments were rhegmatogenous. One patient had a horseshoe tear, one had oral bay tears, two had dialyses, one a giant tear and in one case the break was not specified. Three patients were high myopes. All the patients were young males. The five operable cases all responded satisfactorily to conventional surgery. Histologically apparent adhesions between retinal pigment epithelium and neuroretina have been described in advanced cases of retinitis pigmentosa in older patients and may not be present in younger patients with less advanced disease. Until these adhesions occur patients with retinitis pigmentosa may have no additional protection against retinal detachment.

Adolescent↗