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Adrenal-medullary and adrenal-cortical responses to understimulation and overstimulation: comparison between type A and type B persons.

Male and female university students, classified as Type A and Type B persons with the aid of a questionnaire measuring coronary-prone behavior, were studied while doing mental work under laboratory conditions, characterized by understimulation and overstimulation, and while unoccupied (baseline session). The urinary excretion of adrenaline, noradrenaline and cortisol, heart rate (in the understimulation and baseline conditions) and self-reports were used as indices of arousal. The overall picture showed that both experimental conditions increased arousal, the rise being particularly pronounced for cortisol excretion during understimulation and for adrenaline excretion during overstimulation. Comparison between groups showed that cortisol excretion was higher in Type A than in Type B persons of both sexes during understimulation. Adrenaline excretion was about the same in both sexes (Type A and Type B) during understimulation, but was higher in males than in females during overstimulation. There were no group differences in performance.

Adrenal Cortex

Type A personality and extent of coronary atherosclerosis.

The relation between type A personality and the extent of coronary artery disease was studied in 109 patients who underwent selective coronary angiography. Type A personality as measured with the Jenkins Activity Survey was not correlated with the extent of coronary artery disease as assessed from the number of vessels with 50 percent or greater narrowing of diameter.

Adult

Was Thomas Wolfe a borderline?

The distinction between the two types of borderline proposed by Spitzer, Endicott, and Gibbon--the Schizotypal Personality type of borderline and the Borderline Personality type of borderline--suggests an advance in our thinking about the borderline concept. However, it can be shown, at least in the case of Thomas Wolfe, that an appreciable amount of overlap exists between the two borderline types, in the sense that the same person can load substantially on items from both types. Such findings may tend to blur the distinction between the two types. Also, Wolfe, hailed as a genius, manifested unusual behaviors which are rarely observed and may constitute a form of borderline condition that challenges current diagnosis.

Adult

Automated classification of MMPI profiles into psychotic, neurotic or personality disorder types.

A Fortran program has been developed which can objectively classify Minnesota Multiphasic Inventory (MMPI) profiles as being psychotic, neurotic, personality disorder, or indeterminate types. The method used is a set of configural rules, 'Henrichs' rules for males'. The only input data required are K-corrected T scores, which are the end product of standard scoring techniques. To automate these rules it was necessary to rewrite them so that all decisions were the result of arithmetic comparisons or logical tests using only and, or and not. In particular, examination of the Welsh code, which many rules required, had to be stimulated by the use of several sorted arrays. The program has been carefully tested and is in the use in our computer lab.

Diagnosis, Computer-Assisted

Types of family practice teachers and residents: a comparative study.

A study of personality types using the Myers-Briggs Type Indicator was performed on family practice teachers and residents. The combined group was found to be different from the general medical population. There was a larger percentage of persons who tended to be practical, realistic, present-oriented, organized, and able to deal effectively with factual information. The majority were persons who enjoy seeing immediate results of actions and can made decisions quickly and effectively using whatever information is available. These personality types are similar to those found in the older field of general practice. The residents and faculty were similar in the above respects but a higher percentage of the residents tended to make judgments using impersonal logic and a factual basis for reaching decisions. The faculty, however, had a significantly higher percentage of types who make judgments by considering human values and understanding of people.

Emotions

What kinds of leaders are entering optometry schools?

The purpose of this study was to determine the parameters of leadership of students entering one optometry school, assess the relation between personality types and leadership during optometry school, and forecast potential for leadership beyond school. Personality inventories of 269 students entering University of Houston College of Optometry (UHCO) from 1988 through 1990 were analyzed for personality type according to Gough's two-vector system (V1 = extroversion/introversion; V2 = norm-favoring/norm-doubting) which results in four types or life styles: Alpha, Beta, Gamma, and Delta. Although some sex and ethnic differences were found, most (71%) optometry students were Alphas (extroverted/norm-favoring), accepted leaders who strive to maintain and advance consensual values. Alphas achieved well in classroom and clinic and were student leaders. A lesser number (10%), mostly women, were Gammas; extroverted but norm-questioning, Gammas can provide creative and progressive leadership. Remaining types were Betas (15%) and Deltas (4%), both introverted types who avoid leadership positions. In sum, traditional and, to a lesser degree, innovative leadership potential appears strong among optometry students; they should serve the profession well.

Ethnicity

[Personality traits (type A) in patients with intermittent claudication. 1. Results of the Bortner test].

It has never been considered whether type A (coronary prone) behavior can also be found in patients with peripheral atherosclerotic disease (intermittent claudication). This question has been studied by means of the 14-item (Bortner) questionnaire. The questionnaire was filled out by 10 patients (self-assessment) with coronary artery disease and intermittend claudication, 13 with intermittent claudication alone and 10 with comparably severe, but not arteriovascular disease and independently by their wives (relative's assessment). In the self-assessment the test discriminated significantly between the three groups (Kruskal-Wallis p less than 0.05). The correlation coefficient (Spearman) between expression of type A behavior and extent of atherosclerosis was 0.3720 (p less than 0.02). In the relative's assessment the groups were also differentiated significantly (Kruskal-Wallis p less than 0.05). The correlation coefficient (Spearman) was 0.4080 (p less than 0.009). The results indicate that patients with intermittent claudication demonstrate a predilection for type A behavior, which is more pronounced in those with additional coronary artery disease. The multiple stepwise regression indicated that type A behavior is related to atherosclerosis independently of other factors.

Coronary Disease

[A study of psychological stress: observations of serial performance under the stress induced experimentally by different kind of procedures (author's transl)].

This paper aims to investigate the common changes observed in serial performance irrespective of any stressors experimentally prepared, examining the relations between common changes under stress and personal types of performance. Sixty-six students served as subjects. Measurements of serial reaction time, variance in speed of performance, blockings, corrections, errors, omissions and repetitions were made on simple color naming (experimentally non-stress), competitive color naming (stressor, incongruent stimuli) and high-speed color naming (stressor, controlled high-speed). The results showed that stressors of different kinds induced common changes and the indices of stress implied magnified features of personal types of performance. These findings were discussed in terms of Selye's theory of stress.

Adaptation, Psychological

Effects of semaglutide and empagliflozin on markers of endothelial function in persons with type 2 diabetes: A post hoc analysis of a randomized clinical trial.

AIMS: The endothelium maintains vascular health by regulating blood flow and protecting against inflammatory damage. In type 2 diabetes (T2DM), however, hyperglycemia, hypertension, and hyperlipidemia place a significant burden on the endothelium, potentially leading to atherosclerosis and cardiovascular disease (CVD). While semaglutide and empagliflozin have been shown to reduce CVD risk in T2DM, it remains unclear whether these benefits are mediated by improved endothelial function. This post-hoc analysis explores the effects of these agents on markers of endothelial function, i.e. the reactive hyperaemic index (RHI) and the endothelial-derived cell adhesion molecules (CAMs) E-Selectin, ICAM-1, P-Selectin, and VCAM-1. METHODS: This was a post-hoc analysis of a 32-week randomized trial evaluating the separate and combined effects of semaglutide and empagliflozin on cardio-renal organ damage. One hundred and twenty participants with type 2 diabetes, age&#xa0;&#x2265;&#xa0;50 were randomized to four groups (semaglutide, empagliflozin, the combination or placebo). An increase in RHI and/or a decrease in CAMs were considered beneficial. RESULTS: RHI increased compared to baseline (0.11, 95%CI [0.008;0.21], p&#xa0;=&#xa0;0.03) but not compared to placebo in the semaglutide group (0.11, 95%CI [-0.04;0.24], p&#xa0;=&#xa0;0.16). There was no effect on RHI in the empagliflozin group. Compared to placebo, E-Selectin decreased significantly in the semaglutide and combination groups (-9, 95%CI [-14.1;-5.1] p&#xa0;<&#xa0;0.01 and&#xa0;-&#xa0;9, 95%CI [-14.3; -5.2] p&#xa0;<&#xa0;0.01, respectively). VCAM-1 increased in the same groups, compared to placebo (12.3, 95%CI[2.8;20.8] p&#xa0;=&#xa0;0.01 and 16.2, 95%CI [7.2;24.3], p&#xa0;<&#xa0;0.01, respectively).P-Selectin and ICAM-1 was not significantly affected in any of the groups, compared to placebo (p&#xa0;&#x2265;&#xa0;0.11 and p&#xa0;&#x2265;&#xa0;0.09, respectively). CONCLUSION: Semaglutide improved endothelial function compared to baseline, but not significantly versus placebo, which likely is due to limited power. CAM responses were heterogeneous, suggesting distinct roles in endothelial dysfunction and atherosclerosis. ClinicalTrialsRegister.eu: EudraCT 2019-000781-38.

Aged

Personality and morbid obesity. Implications for dietary management through behavior modification.

Psychological investigations have failed to reveal a distinct personality type or psychodynamic conflict pattern in moderately and massively obese persons. Many of the psychological problems noted in the obese such as anxiety, depression, and poor self-esteem seem to be the result of, rather than the cause of, the obese state. Morbidly obese persons share an addictive behavior pattern that is also seen in persons with other types of addictions. The extent of their obesity points to the strong substance abuse component of the eating disorder. Behavior modification programs aimed at changing problematic eating patterns and teaching self-management skills in relation to food consumption have been moderately successful and have been shown to result in a mean post-treatment weiht loss of seven to 16 pounds. However, the majority of morbidly obese persons will not lose enough weight to make this an effective treatment program for them.

Behavior Therapy

Asthenic personality, myth or reality.

One hundred and seventy five subjects admitted to hospital for neurotic conditions were assessed as to their personality types. Forty seven percent were judged as having personality traits consistent with the diagnosis of asthenic personality disorder. Thirteen of the 138 symptom, life history and psychological test items examined were found to be associated with the asthenic traits. Condensation of these thirteen items by factor analysis showed that two features--anxiety proneness and inability to cope with stress--together defined the disorder.

Anxiety

Overwork.

Overwork, ie, working beyond one's endurance and recuperative capacities, may be a hazard in certain personality types engaged in open-ended occupations. Some persons appear to lack an inner "governor" and for various reasons ignore the commonplace signs that inform one of the need for rest or recreation. If they are engaged in occupations that do not have a finite workday, they may at times exceed their bodies' ability to recover. Clusters of symptoms may then develop, some of which may mimic serious physical ailments. Treatment depends on diagnosing the extent of illness and eliciting the underlying causes. Correction involves enforced rest, therapy that may vary from counseling to hospitalization and specialized treatment, but that must include the reeducation of the person to be aware of and make provision for his physical and emotional needs.

Adult

[Congenital hereditary hypotrychosis. Generalized autosomal dominant hypotrichosis with pili torti (hypotrichosis congenita hereditaria Marie Unna)].

Report on a family with numerous relatives in 7 generations suffering from hypotrichosis congenita hereditaria Marie Unna type. Personal investigations were possible in 29 persons. 19 of them presented the characteristic features of the syndrome with pili torti, generalized inborn hypotrichosis and a type of baldness resembling androgenetic alopecia.

Adolescent