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Pharmaceutical innovation in the United States. Factors affecting future performance.

Fueled by high returns on its investments, the pharmaceutical industry in the United States has flourished for the past 50 years. The regulatory strategy of demanding stringent testing then allowing market-based pricing has allowed private companies to fund ambitious research and development activities with the assurance that these investments will be recovered. However, aggressive managed-care cost-containment strategies threaten the companies' ability to recoup research and development expenses and may affect their willingness to invest in future innovative research.

Diffusion of Innovation↗

Teaching research utilization to baccalaureate nursing students.

This article describes an undergraduate nursing research course that focuses on research utilization. Critical appraisal skills were used to critique articles that formed the bases of a research utilization project. Groups of students formed research utilization teams and developed proposals for identifying, initiating, and evaluating a clinical innovation.

Curriculum↗

The why, what, and how of management innovation.

For organizations like GE, P&G, and Visa, management innovation is the secret to success. But what is management innovation? Why is it so important? And how can other companies learn to become management innovators? This article from expert Gary Hamel answers those questions. A management breakthrough can deliver a strong advantage to the innovating company and produce a major shift in industry leadership. Few companies, however, have been able to come up with a formal process for fostering management innovation. The biggest challenge seems to be generating truly unique ideas. Four components can help: a big problem that demands fresh thinking, creative principles or paradigms that can reveal new approaches, an evaluation of the conventions that constrain novel thinking, and examples and analogies that help redefine what can be done. No doubt there are existing management processes in your organization that exacerbate the big problems you're hoping to solve. So how can you learn to identify them? Start by asking a series of questions for each one. For instance, Who owns the process? What are its objectives? What are the metrics for success? What are the decision-making criteria? How are decisions communicated, and to whom? After documenting these details, ask the people involved with the process to weigh in. This exploration may reveal opportunities to reinventyour management processes. A management innovation, the author says, creates long-lasting advantage when it meets at least one of three conditions: It is based on a novel principle that challenges the orthodoxy; it is systemic, involving a range of processes and methods; or it is part of a program of invention, where progress compounds over time. So far, management in this century isn't much different from management in the previous one, says Hamel. Therein lies the opportunity. You can wait for a competitor to come upon the next great management process and drive you out of business-or you can become a management innovator right now.

Commerce↗

The adoption of corporate restructuring by hospitals.

This study investigates factors associated with the adoption of corporate restructuring by hospitals in Massachusetts, where restructuring occurred much more rapidly than it did nationally. Drawing on studies of management innovation in hospitals, this article hypothesizes that early adopters will differ from those that adopt later on the basis of individual and organizational factors, and that institutional forces will explain later adoption. The findings show no differences between early and later adopters but do show that after an intense period of restructuring, hospitals became less likely to adopt the innovation. The article concludes with a discussion of the impact of reimbursement laws on the adoption pattern and the implications for the diffusion of management innovation, particularly under health care reform.

American Hospital Association↗

Statistical procedures for spatiotemporal neuronal data with applications to optical recording of the auditory cortex.

This article presents new procedures for multisite spatiotemporal neuronal data analysis. A new statistical model - the diffusion model - is considered, whose parameters can be estimated from experimental data thanks to mean-field approximations. This work has been applied to optical recording of the guinea pig's auditory cortex (layers II-III). The rates of innovation and internal diffusion inside the stimulated area have been estimated. The results suggest that the activity of the layer balances between the alternate predominance of its innovation process and its internal process.

Animals↗

Innovation in healthcare: how does credible evidence influence professionals?

The objectives of the present paper are to describe selected findings from a research project on the diffusion and adoption of innovations in primary-care settings. The project design was a comparative case study design exploring four innovations in different settings. The findings are used to explore the influence of evidence on clinical behaviour, particularly how clinical professionals judge credible evidence and take decisions. The article goes on to explore other influences on behaviour and the role of context in shaping processes and behaviour. Finally, the concluding section draws out the relevance of these data for the current changes being implemented in primary care, and raises questions about the implementation of clinical governance and quality improvements.

Diffusion of Innovation↗

Six steps to innovation.

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Attitude of Health Personnel↗