PubMed Health⌕ Search

SEARCH · PubMed Health

Results for “Architectural Accessibility”

Explore indexed PubMed citations for clinical trials, systematic reviews and public health research. Read source abstracts and follow each citation to its original PubMed record.

Quote a phrase for an exact phrase match. Source license links do not imply unrestricted reuse.

At least 55 records · Page 3Linked to original sources
PubMed2004

Insights into facility access.

Hospitals and healthcare premises are extremely busy environments, having to cope with continuous streams of high volume traffic, which includes stretchers and wheelchairs. With time of the essence, it is imperative that staff and patients have easy, reliable access throughout the building.

Architectural Accessibility↗
PubMed2002

Iodine(V) reagents in organic synthesis. Part 2. Access to complex molecular architectures via Dess-Martin periodinane-generated o-imidoquinones.

o-Imidoquinones, a rather rare class of compounds, are prepared from anilides by the action of Dess-Martin periodinane (DMP) and water. Their chemistry has been extensively investigated and found to lead to p-quinones and polycyclic systems of diverse molecular architectures. Applications of this methodology to the total synthesis of the naturally occurring compounds, epoxyquinomycin B and BE-10988, are described. Finally, another rare chemical entity, the ketohydroxyamide moiety, has been accessed through this DMP-based synthetic technology, and its reactivity has been studied. Among its most useful reactions is a set of cascade heterocyclic annulations leading to a variety of polycyclic systems of possible biological relevance.

Alkenes↗
PubMed2005

Perceived barriers to exercise in people with spinal cord injury.

OBJECTIVE: To identify barriers to physical fitness faced by individuals with spinal cord injury preventing them from participating in a physical fitness program. DESIGN: In this cross-sectional study, a survey of barriers to exercise was administered to 72 individuals with spinal cord injury. RESULTS: Although 73.6% of the participants expressed an interest in an exercise program, less than half (45.8%) were currently active in an exercise program. Less than half (47.2%) reported that their physician had recommended an exercise program for them. The most frequently cited concerns about barriers to exercise fell into three areas: (1) intrapersonal or intrinsic (e.g., lack of motivation, lack of energy, lack of interest), (2) resources (e.g., cost of an exercise program, not knowing where to exercise), and (3) structural or architectural (e.g., accessibility of facilities and knowledgeable instructors). More individuals with tetraplegia reported concerns over exercise being too difficult and that health concerns kept them from exercising. Greater number of concerns was significantly related to higher levels of perceived stress. CONCLUSIONS: People with spinal cord injury face multiple barriers to physical fitness in functional, psychological, and architectural domains. Identification of these barriers can facilitate the participation of individuals with spinal cord injury in an exercise program, improving long-term health and wellness.

Adult↗
PubMedDate not supplied

Shopping center wheelchair accessibility: ongoing advocacy to implement the Americans with Disabilities Act of 1990.

Although the regulations of the Americans with Disabilities Act (ADA) of 1990 were phased in by 1992, monitoring and enforcement continue to be problematic. This study of three large shopping centers in the Southwest included one mall that was opened in the mid-1990s, and two malls that were constructed prior to the law (but have undergone recent renovations). Use of the ADA Accessibility Guidelines Checklist for Buildings and Facilities (Architectural and Transportation Barriers Compliance Board [ATBCB], 1992) generated data which were analyzed descriptively to determine the frequency and percent compliance in: parking lots, entrances, ramps, elevators, telephones, restrooms, food courts, and 12 specific store-types. No mall was fully compliant in any area, other than telephone specifications. In other areas, compliance ranged from 0% (ramp slopes in the newer mall) to many areas of 100% compliance (for example, outdoor curb ramps and food court seating spaces and aisles). The implications are that shoppers who are wheelchair mobile cannot count on complete compliance and cannot predict which physical architectural barriers they will find in shopping centers.

Architectural Accessibility↗
PubMed1991

Nondiscrimination on the basis of disability by public accommodations and in commercial facilities--Department of Justice. Final rule.

This rule implements title III of the Americans with Disabilities Act, Public Law 101-336, which prohibits discrimination on the basis of disability by private entities in places of public accommodation, requires that all new places of public accommodation and commercial facilities be designed and constructed so as to be readily accessible to and usable by persons with disabilities, and requires that examinations or courses related to licensing or certification for professional and trade purposes be accessible to persons with disabilities.

Architectural Accessibility↗
PubMed2002

Catalysts for the living insertion polymerization of alkenes: access to new polyolefin architectures using Ziegler-Natta chemistry.

Coordination-insertion polymerization systems have long been superior to their anionic, cationic, and radical polymerization counterparts with regard to stereochemical control. However, until five years ago, these metal-based insertion methods were inferior to ionic and radical mechanisms in the category of living polymerization, which is simply a polymerization that occurs with rapid initiation and negligible chain termination or transfer. In the last half decade, the living insertion polymerization of unactivated olefins has emerged as a powerful tool for the synthesis of new polymer architectures. Materials available today by this route range from simple homopolymers such as linear and branched polyethylene, to atactic or tactic poly(alpha-olefins), to end-functionalized polymers and block copolymers. This review article summarizes recent developments in this rapidly growing research area at the interface of synthetic and mechanistic organometallic chemistry, polymer chemistry, and materials science. While special emphasis is placed on polymer properties and novel polymeric architectures, most of which were inaccessible just a decade ago, important achievements with respect to ligand and catalyst design are also highlighted.

Journal Article↗
PubMed1990

Altered B-lymphocyte membrane architecture indicated by ganglioside accessibility in C3H/HeJ mice.

We have analyzed both the total ganglioside composition and the surface accessibility of C3H/HeN B lymphocytes and C3H/HeJ B lymphocytes. Seventeen individual resorcinol-positive moieties were visualized by two-dimensional thin-layer chromatography of the purified gangliosides from both strains. Complete homology between strains was seen in the patterns of total gangliosides purified from the endotoxin-responsive and -hyporesponsive strains, with only minor differences in the relative concentrations of four gangliosides. In comparison, only 12 individual gangliosides were accessible to surface labeling following galactose oxidase treatment in these same strains, suggesting that some gangliosides are masked at the cell surface in both strains. However, labeling of the more polar components was greatly reduced in the endotoxin-hyporesponsive (C3H/HeJ) strain, suggesting that these gangliosides have decreased accessibility to galactose oxidase at the cell surface. Therefore, while the total ganglioside compositions of the two strains were nearly equivalent, there were dramatic differences in ganglioside surface accessibility. These findings indicate that an alteration in membrane structure that is associated with the endotoxin hyporesponsiveness observed in C3H/HeJ B lymphocytes exists.

Animals↗
PubMed2001

Rapid Access to Complex Molecular Architectures via o-Azaquinones We thank Dr. D. H. Huang, G. Siuzdak, and Dr. R. Chadha for NMR spectroscopic, mass spectrometric, and X-ray crystallographic assistance, respectively. This work was supported financially by The Skaggs Institute for Chemical Biology, the National Institutes of Health (USA), a predoctoral fellowship from the National Science Foundation (P.S.B), and grants from ArrayBiopharma, Pfizer, Glaxo, Merck, Schering Plough, Hoffmann-La Roche, Boehringer Ingelheim, DuPont, and Abbott Laboratories.

Explore the source record for details and available documents.

Journal Article↗