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At least 757 records · Page 42Linked to original sources
PubMed1993

Acute toxicological effects of ingested tooth whiteners in female rats.

Tooth whiteners are considered as cosmetic agents to be used for bleaching teeth. Since tooth whitener may be swallowed during the whitening procedure, studies were conducted to determine whether ingestion of tooth whitener containing carbamide peroxide resulted in toxic effects. Adult female rats were used, and vaginal smears were examined daily to determine whether the animals were ovulating. Following an overnight fast, a single bolus of a commercial tooth whitener (5 g of tooth whitener/kg fasting body weight) was administered by gavage. Control rats received de-ionized water. After 2 h, mean respirations per min of animals receiving the tooth whitener Quik Start (contains 35% carbamide peroxide) decreased from 169 to 55, and body temperature decreased from 38.4 to 34 degrees C. Other distress signs included: labored breathing, loss of righting reflex, partial eye closure, bloody urine, and incontinence. Three of 22 animals (3/22) died within 48 h, of gastric hemorrhaging. Eight/10 rats stopped ovulating. At necropsy 2 weeks post-dosing, 10/19 animals had grossly bloated stomachs, and mucosal necrosis was observed histologically in 3. Animals receiving White & Brite or Nu-Smile (containing 10 or 15% carbamide peroxide, respectively) exhibited similar but milder symptoms. The data indicate that ingestion of large doses of commercial preparations of tooth whiteners may be acutely toxic, sometimes fatal, to female laboratory rats.

Animals↗
PubMed2004

Bleaching agents.

Explore the source record for details and available documents.

Carbamide Peroxide↗
PubMed2004

The measurement of degradation and wear of three glass ionomers following peroxide bleaching.

OBJECTIVES: To investigate, for three glass ionomer dental materials, the effects of a hydrogen peroxide solution on the elution of key elements, and the effects of a novel 6% hydrogen peroxide tooth whitening gel on subsequent wear rates with a toothpaste slurry. METHODS: Discs specimens of three glass ionomers (ChemFlex, Fuji II and Ketac-Fil) were prepared. One set of discs was exposed to either 6% hydrogen peroxide in phosphate buffer, phosphate buffer, water, a carbonated beverage or 38% orthophosphoric acid for 60 min. The ions eluted from the discs were determined by inductively coupled plasma-optical emmision spectroscopy. A second set of discs were conditioned with either a 6% hydrogen peroxide gel (30 min), water (30 min), a carbonated beverage (2 min) or 38% orthophosphoric acid gel (2 min) followed by a three-body abrasive wear treatment (2 min) with a toothpaste slurry. Changes in height of the samples were measured with a digital comparitor. The conditioning and abrasive cycles were repeated thirteen times. RESULTS: For the elution study, the solutions gave only minor release of sodium except orthophosphoric acid which showed increased elution levels of aluminium, silicon and sodium ions. For the wear study, the orthophosphoric acid gave the highest level of wear whilst for the other treatments there were no statistical significant differences in the level of wear (one-way ANOVA). CONCLUSIONS: A 6% hydrogen peroxide solution did not cause significant dissolution, and a novel 6% hydrogen peroxide tooth whitening gel did not significantly increase the three-body wear rate of any of the materials tested.

Aluminum↗
PubMed1991

pH variation among materials used for intracoronal bleaching.

Intracoronal bleaching of pulpless teeth with 30% hydrogen peroxide may result in external cervical root resorption. One of several suggested etiological factors associated with this complication is the pH of the bleaching materials. Because the available data on the pH values of bleaching materials were conflicting, it was the purpose of this study to measure the pH of the materials commonly used for bleaching pulpless teeth. The pH of different concentrations of sodium perborate and 30% hydrogen peroxide, alone or in combination, were measured for a period of 14 days. Sodium perborate was confirmed to be alkaline, whereas 30% hydrogen peroxide was acidic. The pH of the materials when mixed together gradually changed from acidic to alkaline as the concentration of sodium perborate was increased. A thick clinical consistency mixture of both materials was alkaline, and its alkalinity increased with time. These results do not support the theory relating bleaching-induced root resorption to an acidic pH of the bleaching pastes.

Borates↗
PubMed2005

An overview of bleaching techniques: 3. In-surgery or power bleaching.

The use of in-surgery bleaching techniques has increased recently within the profession following the introduction of various new systems. Many dentists and patients alike prefer the in-surgery procedures to lighten teeth as it takes the responsibility for the procedure firmly away from the patient to the dentist; a situation with which both sides may be more comfortable. This article will review various in-surgery or power bleaching procedures. In addition, it will detail the procedure involved and how and when to combine bleaching techniques.

Burns, Chemical↗