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[Surgical outcomes of vitrectomy for retinal detachment due to macular hole with proliferative vitreoretinopathy].

We retrospectively studied surgical outcomes in 13 patients (13 eyes) who underwent vitrectomy for proliferative vitreoretinopathy (PVR) due to macular hole. While the success rate of the initial surgery was only 46% (6 eyes), retinal reattachment was ultimately obtained in 92% (12 eyes) with additional surgery. Reattachment rate in the initial was poor in eyes with posterior staphyloma. It was better in eyes treated with macular buckling and/or scleral encircling, and in eyes without iatrogenic retinal tears. These results indicate that appropriate treatment for the macular hole as well as extensive removal of vitreous gel and vitreoretinal traction are necessary in order to obtain the successful results in vitrectomy for PVR due to macular hole.

Aged↗

[Vitrectomy: method for treating of vitreo-corneal adhesions in children].

Vitreocorneal adhesions were removed by anterior vitrectomy in 37 children. In 19 patients the adhesions developed after removal of cataracts and in 18 after penetrating wounds of the cornea. Vitrectomy was carried out 1 month to 6 years after the diagnosis, the mean term was 1.4 years. The intervention normalized the ratio between ocular chambers, improved the appearance, and appreciably improved the visual acuity.

Adolescent↗

Sympathetic uveitis after trauma and vitrectomy.

A case is describes in which the earliest clinical manifestations of sympathetic uveitis that occurred after trauma and pars plana vitrectomy were confined primarily to the retina, retinal pigment epithelium, and choroid posteriorly, and resembled focal lesions of acute posterior multifocal placoid pigment epitheliopathy. Similar focal lesions were noted on gross examination of the enucleated inciting eye. Histopathological examination revealed that these lesions were caused by focal choroidal granulomas and overlying Dalen-Fuchs nodules. Sympathetic ophthalmia was also noted in four other patients in whom the condition developed after trauma and vitrectomy.

Adult↗

Corneal complications after closed vitrectomy through the pars plana.

A retrospective study of 150 patients who underwent closed vitrectomy through the pars plana evaluated the incidence and character of postoperative corneal complications. Corneal changes developed in 43% of patients. Thirty patients had significant corneal complications, half of which resolved with treatment. Fourteen patients had complications that necessitated corneal surgery or resulted in loss of useful vision. Diabetic patients were at greatest risk for corneal problems, particularly postoperative epithelial defects. Intraoperative lensectomy was the only other factor that increased the corneal complication rate. The importance of early recognition and therapy for corneal changes after vitrectomy becomes apparent.

Corneal Diseases↗

Pars plana vitrectomy. Treatment for tractional macula detachment secondary to proliferative diabetic retinopathy.

Pars plana vitrectomies were performed on 43 eyes with traction macular detachment secondary to proliferative diabetic retinopathy. Anatomic success, as judged by reattachment of the macula, occurred 28 (65%) eyes. Improved visual acuity occurred in 11 (26%) eyes. Severe complications occurring after vitrectomy included moderate to severe rubeosis iridis diabetica (28%), neovascular glaucoma (16%), vitreous hemorrhage (49%), and phthisis bulbi (14%). Eyes that received scatter photocagulation therapy at some time prior to macular detachment had a substantially lower incidence of successful postoperative reattachment of the macula than eyes never treated with photocoagulation.

Adolescent↗

Intraocular fluid dynamics. Measurements following vitrectomy and intraocular sulfur hexafluoride administration.

Partial vitrectomies were performed in rabbits, replacing 40% of initial vitreous volume with 100% sulfur hexafluoride, and concentrations of sodium, potassium, calcium, magnesium, ascorbate, and protein were determined in aqueous and vitreous at 10, 14, 21, 28, 56, and 110 days. There were significant increases of potassium, calcium, magnesium, and protein above control values at varying times throughout the study. Vitreous potassium concentration was decreased at 14 and 21 days. All other measurements were similar to control values. Results of studies indicate that, following vitrectomy in rabbits, the blood-retinal barrier can re-form in 14 days and blood-aqueous barrier in ten days. However, a greater than normal exchange diffusion of these measured substances occurs between aqueous and vitreous through 21 days. Four eyes with cataracts, vitreous membranes, and/or detached retinas demonstrated elevated aqueous and vitreous protein concentrations through 110 days, although other measurements returned to normal levels.

Animals↗

Bacterial collagenase. Proposed adjunct to vitrectomy with membranectomy.

Clostridiopeptidase A digested preretinal cicatricial tissue without causing morphological alteration of normal retina during a 30-minute incubation in the rabbit. Light and transmission electron microscopy were used to determine effects on the inner limiting membrane and retinal ganglion and Müller's cells and to evaluate enzyme digestion of preretinal scarring. Removal of the injected collangenase by vitrectomy resulted in normal electroretinograms and retinal morphology 48 hours postoperatively. If the enzyme was left in the eye for 24 hours, lens opacities, partial erosion of the inner limiting membrane, and extensive hemorrhage resulted. The specificity of action of the collagenase is due to the high degree of purity of the enzyme used and a substantial biochemical difference between scar collagen and basement membrane collagen. The injection of purified collagenase capable of digesting vitreal scar tissue while leaving the retina undamaged could represent a new approach to vitrectomy, specifically to facilitate certain cases of membranectomy.

Animals↗

The lens influence on diabetic vitrectomy results. Report of a prospective randomized study.

Fifty cases with clear lenses that were undergoing pars plana vitrectomy for diabetic retinopathy complications were randomly assigned to either retaining the lenses or to having lensectomy at the time of the vitrectomy. Management of the lens did not seem to have a major influence on the postoperative visual function. However, the aphakic cases had a higher incidence of elevated intraocular pressures and peripheral iris rubeosis at the six-month follow-up examination. The incidence of neovascular glaucoma was also higher in the aphakic group.

Adult↗

Stability of pars plana vitrectomy results for diabetic retinopathy complications. A comparison of five-year and six-month postvitrectomy findings.

The visual and anatomical findings in 164 eyes six months after vitrectomy were compared with the findings in these same eyes five years after vitrectomy. Those with good results tended to remain stable. Of the 77 eyes that had 6/60 or better visual acuity at the six-month examination, 64 (83%) continued to have as good or better vision at the five-year examination. Following the six-month examination, 85% of the irides without rubeosis remained without rubeosis, 84% of the vitreous cavities that were clear remained clear, and 94% of the maculae that were attached remained attached.

Adult↗

[A method of standardizing the results of quantitative chemical investigations on material gained from vitrectomy (author's transl)].

In this study a method is described which allow conclusions to be drawn from the concentration of chemical substances in the material gained from vitrectomy in relation to the content of these substances in the whole vitreous body. In 16 pairs of human postmortem eyes enucleated 3-5 h after death one eye of each pair was subjected to vitrectomy under constant suction and infusion pressure and cutting rate; the duration of surgery varied (3-9 min) and in each fellow eye the whole vitreous body was removed. Comparison of the different concentrations of chemical substances in the samples showed that they could be correlated.

Eye Proteins↗

Vitrectomy-instrumentation-system MS 7.

An instrumentation-system (MS 7) for open-sky- as well as for pars-plana-vitrectomy is described. The intraocular canula is equipped with a special rotating cutting device. Suction is generated by a suction-pump in the power supply unit. Intraocular illumination is obtained by a detachable light pipe on the vitrectomy-canula or-for the bimanual technique-by a special hand-piece with infusion and fiber optic illumination. The infusion-canula in the hand-piece can be replaced by a micro-scissor with infusion-channel. Despite the motor the whole system can be easy cleaned and sterilized.

Humans↗

Elevation of intraocular pressure after pars plana vitrectomy.

To determine the incidence and causes of increased intraocular pressure (IOP) after pars plana vitrectomy with the vitrophage, we studied 118 eyes under-going vitrectomy during a one-year period. Fifty-one (43%) were in diabetic patients; 67 (57%) were in nondiabetics. Of the entire group, 33 (28%) developed a postoperative increase in IOP, which was defined as a rise in IOP of at least 10 mm Hg above the preoperative level by applanation tonometry. Of the diabetic eyes 25 (49%) developed increased IOP; 11 (22%) of these eyes required surgical intervention for control of IOP. Of the nondiabetic eyes eight (12%) developed increased IOP postoperatively; all were either transiently elevated or medically controllable. Postoperative rubeosis iridis occurred only in diabetic eyes.

Adolescent↗

Pars plana vitrectomy in the management of endogenous Candida endophthalmitis.

A 27-year-old white man had endogenous Candida endophthalmitis with fungi in the vitreous cavity, presumably caused by hematogenous spread related to drug abuse, and was treated by pars plana vitrectomy and antifungal medications administered systemically after surgery. There was no evidence of other systemic involvement, and excision of fungi from the vitreous cavity confirmed the clinical diagnosis and determined the sensitivity of this fungus to antifungal medications. The fungus was sensitive to flucytosine (5-FC), which the patient received orally since it was less toxic to body tissues than amphotericin B. The intraocular infection cleared rapidly after vitrectomy, and visual acuity returned to 6/5 (20/15).

Adult↗

Recurrent amyloid involvement in the virreous body after vitrectomy.

A patient with vitreous opacification due to primary familial amyloidosis underwent bilateral vitrectomy via the pars plana with excellent visual results. Two and one half years later opacification of the vitreous body recurred in the retrolental area bilaterally, necessitating a repeat vitrectomy in the left eye. This opacity was successfully removed from the posterior surface of the lens without apparent damage to the lens.

Aged↗

Glaucoma occurring after closed vitrectomy.

Six of 20 eyes developed postoperative glaucoma within two to ten days after closed vitrectomy for vitreous hemorrhage. Intraocular pressure was greater than 40mm Hg in all six eyes, and three developed pressure greater than 60 mm Hg. Intraocular pressure in four eyes was controlled with medical antiglaucoma therapy and two eyes required anterior chamber irrigation. Six months postoperatively three of the eyes had normal pressures, one was hypotonous, and two developed increased intraocular pressure secondary to angle neovascularization. Three of the 14 eyes that did not develop glaucoma developed a cellular accumulation in the anterior chamber. The glaucoma was caused mainly by obstruction of the trabecular meshwork by degenerated red blood cells known as ghost cells. The cells may be identified by phase-contrast examination of anterior chamber aspirates. Glaucoma can be prevented through irrigation of the vitreous cavity at the time of vitrectomy ensuring that no cells and debris are left behind to migrate into the anterior chamber and obstruct the trabecular meshwork. This type of glaucoma is caused mainly by ghost cells, whereas hemolytic glaucoma is caused mainly by macrophages and red blood cell debris.

Eye Diseases↗

Results of vitrectomy for rare proliferative and hemorrhagic diseases.

We compiled the results of pars plana vitrectomy in rare proliferative and hemorrhagic diseases. In retinal vasculitis of unknown origin (perhaps Eales' disease), six out of seven eyes had visual improvement; in sickle cell disease, two out of three eyes improved. Three eyes with presumed toxocariasis were successfully treated. In retrolental fibroplasia (RLF), only lighter degrees of the cicatricial stage with traction detachments can be treated. Some cases may simulate Coats' disease. There are also cases which simulate the typical picture of RLF, where there is no history of prematurity or oxygen usage. Five patients with RLF were treated, three of these successfully. Cryoglobulinemia (one case) and hereditary hemorrhagic telangiectasia (one case) were successfully treated. Senile macular degeneration can also be an indication for vitrectomy (two out of three eyes were successfully treated).

Adolescent↗