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Robotics for surgery.

Robotic technology is enhancing surgery through improved precision, stability, and dexterity. In image-guided procedures, robots use magnetic resonance and computed tomography image data to guide instruments to the treatment site. This requires new algorithms and user interfaces for planning procedures; it also requires sensors for registering the patient's anatomy with the preoperative image data. Minimally invasive procedures use remotely controlled robots that allow the surgeon to work inside the patient's body without making large incisions. Specialized mechanical designs and sensing technologies are needed to maximize dexterity under these access constraints. Robots have applications in many surgical specialties. In neurosurgery, image-guided robots can biopsy brain lesions with minimal damage to adjacent tissue. In orthopedic surgery, robots are routinely used to shape the femur to precisely fit prosthetic hip joint replacements. Robotic systems are also under development for closed-chest heart bypass, for microsurgical procedures in ophthalmology, and for surgical training and simulation. Although results from initial clinical experience is positive, issues of clinician acceptance, high capital costs, performance validation, and safety remain to be addressed.

Biomedical Engineering↗

GIS and remote sensing applications in the assessment of change within a coastal environment in the Niger Delta region of Nigeria.

In the last decades, the Niger Delta region has experienced rapid growth in population and economic activity with enormous benefits to the adjacent states and the entire Nigerian society. As the region embarks upon an unprecedented phase of economic expansion in the 21st century, it faces several environmental challenges fuelled partly by the pressures caused by human activities such as oil and gas exploration, housing development, and road construction for transportation, economic development and demographic changes. This continued growth has resulted in environmental problems such as coastal wetland loss, habitat degradation, and water pollution, gas flaring, destruction of forest vegetation as well as a host of other issues. This underscores the urgent need to design new approaches for managing remote costal resources in sensitive tropical environments effectively in order to maintain a balance between coastal resource conservation and rapid economic development in developing countries for sustainability. Notwithstanding previous initiatives, there have not been any major efforts in the literature to undertake a remote sensing and GIS based assessment of the growing incidence of environmental change within coastal zone environments of the study area. This project is an attempt to fill that void in the literature by exploring the applications of GIS and remote sensing in a tropical coastal zone environment with emphasis on the environmental impacts of development in the Niger Delta region of Southern Nigeria. To deal with some of the aforementioned issues, several research questions that are of great relevance to the paper have been posed. The questions include, Have there been any changes in the coastal environment of the study area? What are the impacts of the changes? What forces are responsible for the changes? Has there been any major framework in place to deal with the changes? The prime objective of the paper is to provide a novel approach for assessing the state of coastal environments while the second objective seeks a contribution to the literature. The third objective is to provide a decision support tool for coastal resource managers in the assessment of environmental impacts of development in tropical areas. The fourth objective is to assess the extent of change in a tropical ecosystem with the latest advances in geo-spatial information technologies and methods. In terms of methodology, the paper draws from primary and census data sources analyzed with descriptive statistics, GIS techniques and remote sensing. The sections in the paper consist of a review of the major environmental effects and factors associated with the problem: initiatives and mitigation measures. The project offers some recommendations as part of the conservation strategies. In spite of concerted efforts by managers to address the problems, results revel that the study area experienced some significant changes in its coastal environments. These changes are attributed to socio-economic and environmental variables.

Demography↗

Distance education: strategies for maintaining relationships.

Experience with Australian Aboriginal and Torres Strait Islander students in the Bachelor of Applied Health Science (BAppHSc) course suggests that one of the key elements for students is the sense of relationship built up through Problem Based Learning (PBL). Failure to retain students is more likely to be related to personal than academic concerns. The low attrition rate is largely attributed to the sense of community and support the course generates. In 1997, the Centre for Indigenous Health, Education and Research offered the BAppHSc to rural Queensland. Campuses were opened in the Torres Strait and Cairns, with 9 and 5 students respectively. The course consisted of PBL sessions, fixed resource sessions provided by local staff or guest lecturers, video-conferencing and the use of videos, or text. Face-to-face contact hours were concentrated into two blocks of one and two weeks respectively, plus one day per week. Course materials such as journal articles and texts were provided. The nine Torres students and three Cairns students completed the first semester. This paper discusses the differences between the centres and examines strategies for maintaining the sense of relationship in distance education settings. In 1999 applications from other remote areas are challenging the model further. Multiple technologies are envisaged and discussed. In addition, similar methods are being applied to post graduate courses and collaboration with other institutions in the Pacific suggested. This would allow cross crediting of such course-work into a range of courses and institutions, reducing duplication and increasing options.

Australia↗

Volcano remote sensing with ground-based spectroscopy.

The chemical compositions and emission rates of volcanic gases carry important information about underground magmatic and hydrothermal conditions, with application in eruption forecasting. Volcanic plumes are also studied because of their impacts upon the atmosphere, climate and human health. Remote sensing techniques are being increasingly used in this field because they provide real-time data and can be applied at safe distances from the target, even throughout violent eruptive episodes. However, notwithstanding the many scientific insights into volcanic behaviour already achieved with these approaches, technological limitations have placed firm restrictions upon the utility of the acquired data. For instance, volcanic SO(2) emission rate measurements are typically inaccurate (errors can be greater than 100%) and have poor time resolution (ca once per week). Volcanic gas geochemistry is currently being revolutionized by the recent implementation of a new generation of remote sensing tools, which are overcoming the above limitations and are providing degassing data of unprecedented quality. In this article, I review this field at this exciting point of transition, covering the techniques used and the insights thereby obtained, and I speculate upon the breakthroughs that are now tantalizingly close.

Environmental Monitoring↗

Land use change analysis of Beykoz-Istanbul by means of satellite images and GIS.

Management and planning of the natural environment requires spatially accurate and timely information on land use patterns. With repetitive satellite coverage, the rapid evolution of computer technology and the integration of satellite and spatial data, the development of land use applications have become ubiquitous. The integration of Remote Sensing (RS) and Geographic Information Systems (GIS) has been widely applied and recognized as a powerful and effective tool in detecting land use change in urban areas. This paper presents the land use change analysis of the Beykoz region, which is the second largest administrative district of Istanbul. Land use changes and their impacts are monitored using Landsat (MSS - TM) and Spot 5 satellite data in the period of 1975-2001. The independent classification of each satellite image was used as a change analysis method and the resulting images were analyzed with GIS techniques. The results showed that forest area of Beykoz decreased from 80.55% to 70.5% between 1975 and 1984 and during the 1984-2001 periods, the forested area decreased from 70.5% to 68.86% and the urban growth rate was 4.65%.

Conservation of Natural Resources↗

[Calculation of soil water erosion modulus based on RUSLE and its assessment under support of artificial neural network].

With Hengshan County of Shanxi Province in the North Loess Plateau as an example, and by using ETM + and remote sensing data and RUSLE module, this paper quantitatively derived the soil and water loss in loess hilly region based on "3S" technology, and assessed the derivation results under the support of artificial neural network. The results showed that the annual average erosion modulus of Hengshan County was 103.23 t x hm(-2), and the gross erosion loss per year was 4. 38 x 10(7) t. The erosion was increased from northwest to southeast, and varied significantly with topographic position. A slight erosion or no erosion happened in walled basin, flat-headed mountain ridges and sandy area, which always suffered from dropping erosion, while strip erosion often happened on the upslope of mountain ridge and mountaintop flat. Moderate rill erosion always occurred on the middle and down slope of mountain ridge and mountaintop flat, and weighty rushing erosion occurred on the steep ravine and brink. The RUSLE model and artificial neural network technique were feasible and could be propagandized for drainage areas control and preserved practice.

China↗

Development of a functionalized xenon biosensor.

NMR-based biosensors that utilize laser-polarized xenon offer potential advantages beyond current sensing technologies. These advantages include the capacity to simultaneously detect multiple analytes, the applicability to in vivo spectroscopy and imaging, and the possibility of "remote" amplified detection. Here, we present a detailed NMR characterization of the binding of a biotin-derivatized caged-xenon sensor to avidin. Binding of "functionalized" xenon to avidin leads to a change in the chemical shift of the encapsulated xenon in addition to a broadening of the resonance, both of which serve as NMR markers of ligand-target interaction. A control experiment in which the biotin-binding site of avidin was blocked with native biotin showed no such spectral changes, confirming that only specific binding, rather than nonspecific contact, between avidin and functionalized xenon leads to the effects on the xenon NMR spectrum. The exchange rate of xenon (between solution and cage) and the xenon spin-lattice relaxation rate were not changed significantly upon binding. We describe two methods for enhancing the signal from functionalized xenon by exploiting the laser-polarized xenon magnetization reservoir. We also show that the xenon chemical shifts are distinct for xenon encapsulated in different diastereomeric cage molecules. This demonstrates the potential for tuning the encapsulated xenon chemical shift, which is a key requirement for being able to multiplex the biosensor.

Avidin↗

Intelligent infrastructure for sustainable potable water: a roundtable for emerging transnational research and technology development needs.

PROBLEM STATEMENT: Recent commercial and residential development have substantially impacted the fluxes and quality of water that recharge the aquifers and discharges to streams, lakes and wetlands and, ultimately, is recycled for potable use. Whereas the contaminant sources may be varied in scope and composition, these issues of urban water sustainability are of public health concern at all levels of economic development worldwide, and require cheap and innovative environmental sensing capabilities and interactive monitoring networks, as well as tailored distributed water treatment technologies. To address this need, a roundtable was organized to explore the potential role of advances in biotechnology and bioengineering to aid in developing causative relationships between spatial and temporal changes in urbanization patterns and groundwater and surface water quality parameters, and to address aspects of socioeconomic constraints in implementing sustainable exploitation of water resources. WORKSHOP OUTCOMES: An interactive framework for quantitative analysis of the coupling between human and natural systems requires integrating information derived from online and offline point measurements with Geographic Information Systems (GIS)-based remote sensing imagery analysis, groundwater-surface water hydrologic fluxes and water quality data to assess the vulnerability of potable water supplies. Spatially referenced data to inform uncertainty-based dynamic models can be used to rank watershed-specific stressors and receptors to guide researchers and policymakers in the development of targeted sensing and monitoring technologies, as well as tailored control measures for risk mitigation of potable water from microbial and chemical environmental contamination. The enabling technologies encompass: (i) distributed sensing approaches for microbial and chemical contamination (e.g. pathogens, endocrine disruptors); (ii) distributed application-specific, and infrastructure-adaptive water treatment systems; (iii) geostatistical integration of monitoring data and GIS layers; and (iv) systems analysis of microbial and chemical proliferation in distribution systems. IMPACT: This operational framework is aimed at technology implementation while maximizing economic and public health benefits. The outcomes of the roundtable will further research agendas in information technology-based monitoring infrastructure development, integration of processes and spatial analysis, as well as in new educational and training platforms for students, practitioners and regulators. The potential for technology diffusion to emerging economies with limited financial resources is substantial.

Conservation of Natural Resources↗

Nucleic acid sensing by regenerable surface-associated isothermal rolling circle amplification.

A novel method for regenerating biosensors has been developed in which the highly specific detection of nucleic acid sequences is carried out using molecular padlock probe (MPP) technology and surface-associated rolling circle amplification (RCA). This technique has a low occurrence of false positive results when compared to polymerase chain reaction, and is an isothermal reaction, which is advantageous in systems requiring low power consumption such as remote field sensing applications. Gold-sputtered 96-well polystyrene microplates and a fluorescent label were used to explore the detection limits of the surface-associated RCA technique, specificity for different MPP, conditions for regeneration of the biomolecular sensing surface, and reproducibility of measurements on regenerated surfaces. The technique was used to create highly selective biomolecular surfaces capable of discriminating between DNA oligonucleotides with sequences identical to RNA from infectious salmon anemia (ISA) and infectious hematopoietic necrosis (IHN) virus. As little as 0.6 fmol of circularized MPP was detectable with this fluorimetric assay. The sensing layers could be reused for at least four cycles of amplification using thermal denaturation, with less than 33% decrease in RCA response over time. Because the nucleic acid product of the test is attached to a surface during amplification, the technique is directly applicable to a variety of existing sensing platforms, including acoustic wave and optical devices.

Biosensing Techniques↗

GIS tools for tick and tick-borne disease occurrence.

Geographic information systems (GIS), their fundamental components and technologies are described. GIS is a computer-based system enabling the storage, integration, query, display and analysis of data using information on data location. Further, remote sensing (RS) methods and their application in landscape characterization are described. Landscape pattern analysis, combined with statistical analysis, allows the determination of landscape predictors of disease risk. This makes RS/GIS a powerful set of tools for disease surveillance, enabling the prediction of potential disease outbreaks and targeting intervention programs. The 'pre-GIS era' is briefly described including the early mapping of tick distribution, analyses and the display of biogeographical and medical data. The theory of natural focality of diseases (NFD) is explained and its significance in tick-borne diseases (TBD) research is discussed. Many problems of tick ecology and TBD epidemiology and epizootology have been addressed by means of GIS and examples of these studies are presented and discussed.

Animals↗

Galileo Avionica's technologies and instruments for planetary exploration.

Several missions for planetary exploration, including comets and asteroids, are ongoing or planned by the European Space Agencies: Rosetta, Venus Express, Bepi Colombo, Dawn, Aurora and all Mars Programme (in its past and next missions) are good examples. The satisfaction of the scientific request for the mentioned programmes calls for the development of new instruments and facilities devoted to investigate the body (planet, asteroid or comet) both remotely and by in situ measurements. The paper is an overview of some instruments for remote sensing and in situ planetary exploration already developed or under study by Galileo Avionica Space & Electro-Optics B.U. (in the following shortened as Galileo Avionica) for both the Italian Space Agency (ASI) and for the European Space Agency (ESA). Main technologies and specifications are outlined; for more detailed information please refer to Galileo Avionica's web-site at: http://www.galileoavionica.com .

Astronomy↗

[Use of satellites for public health purposes in tropical areas].

The epidemiological hallmark of the new millennium has been the emergence or recrudescence of transmissible diseases with high epidemic potential. Disease tracking is becoming an increasingly global task requiring implementation of more and more sophisticated control strategies and facilities for sustainable development. A promising initiative involves the use of satellite technology to monitor and forecast the spread of disease. The Health Early Warning System (HEWS) was designed based on successful application of satellite data in food programs as well as in other areas (e.g. weather, farming and fishing). The HEWS integrates data from communications, remote-sensing and positioning satellites. The purpose of this review is to present the main studies containing satellite data on public health in tropical areas. Satellite data has allowed development of more reactive epidemiological tracking networks better suited to increasing population mobility, correlation of environmental factors (vegetation index, rainfall and ocean surface color) with human, animal and insect factors in epidemiological studies and assessment of the role of such factors in the development or reappearance of disease. Satellite technology holds great promise for more efficient management of public health problems in tropical areas.

Cholera↗

Fiber optics in medicine.

The most significant and prevalent applications of fiber optics in medicine are in the imaging and illumination components of endoscopes. Flexible and rigid multifibers composed of step-index fibers and graded-index imaging rods are extensively used for visualization of internal organs and tissue which are accessible through natural openings or transcutaneously. This article reviews the evolution of the fiber-optic endoscope over the past 20 years. The fabrication techniques of optical fibers for imaging and illumination are considered in juxtaposition to their current applications in communications with emphasis on the different technologies involved. The design of distinct endoscopes is described with a detailed review of their use in various medical specialities. Low-loss optical fibers are employed to transmit laser energy for surgery and photocoagulation. Multicolor laser light is transmitted through a single thin optical fiber to provide adequate illumination for viewing and color photography. Past attempts to develop plastic imaging multifibers and their future potential viewing and color photography. Past attempts to develop plastic imaging multifibers and their future potential are discussed. Other uses of fiber optics in medicine include remote spectrophotometry, pressure and position sensing, or scintillation counting. These and other applications, such as intravascular pressure transducers and in vivo oximeters, are described.

Bronchoscopes↗

Invisible Threats, Relentless Hunters: Biosurveillance of Airborne Plant Pathogens.

Airborne dispersal enables plant pathogens to travel across fields, regions, and continents, fueling rapid epidemics and emerging disease threats. Biosurveillance, the systematic monitoring of airborne inoculum, offers the opportunity to detect pathogens before symptoms appear and informs timely, risk-based management. Recent advances in air sampling, molecular diagnostics, metagenomics, and imaging technologies have expanded the scale and resolution of pathogen monitoring, from single-species qPCR assays to community-level aerobiome surveys. Integration of biosurveillance data with decision-support systems, remote sensing, and artificial intelligence is transforming early-warning capabilities and providing novel insights into pathogen ecology, evolution, and fungicide resistance. Yet major challenges remain, including assay standardization, data interpretation, and translation into actionable tools for growers. This review synthesizes current approaches, highlights case studies in which biosurveillance has advanced disease management, and outlines future directions toward coordinated surveillance networks and precision agriculture applications.

Air Microbiology↗

Computerized thermography. The emergence of a new diagnostic imaging modality.

Medical thermology is a relatively new diagnostic imaging modality that is based on thermography and has just recently gained acceptance by the medical community at large. In fact, the first comprehensive book on thermology appeared in press just a few months ago (2). Thermography is the recording and displaying of images that depict the distribution of temperature on the skin surface of patients. Thermology is the systematic interpretation of clinical thermograms. The leading thermographic technique is now based on remote infrared sensing. using digitizing techniques and microcomputers, the images can be processed to facilitate better thermological interpretation. This paper presents a brief account of the evolvement of this imaging modality, its current technology and medical uses, and its potential to become a major diagnostic tool in a large number of clinical situations. Finally, we will attempt to assess the overall role and place of thermology in medicine while also pointing out the need for fundamental thermological research to support the current empirical diagnostic applications.

Computers↗

Vestibular telemedicine and rehabilitation. Applications for virtual reality.

This paper will discuss the use of Virtual Reality (VR) technologies in the rehabilitation of patients with vestibular disorders and in the provision of remote medical consultations for those patients. Patients with a vestibular problem are very common (vertigo is the second most common neurological complaint after headache) and yet there are very few vestibular neurotologists: specialists in their diagnosis and treatment. New treatments for various disorders causing vertigo now exist. This means that appropriate diagnosis can significantly improve patients' well-being. Remote medical diagnosis and treatment facilities could make the few vestibular disorder specialists much more available to patients. An analysis of the technological and economic factors influencing the provision of this service is necessary. The main long term effect of many vestibular disorders is damage to the sensing apparatus of the inner ear. The damage can lead to inappropriate interaction between visually driven orientation sensing and sensing of orientation by the inner ear. The consequence for the patient is vertigo (a sensation of turning), motion sickness and imbalance. Current rehabilitation efforts are intended to drive the nervous system to adapt to the disordered vestibular input. Adaptation appears to occur slowly in many subjects, even those within rehabilitation programs. An appropriately designed VR experience could greatly increase the rate of adaptation in these patients.

Humans↗

Gas-phase databases for quantitative infrared spectroscopy.

The National Institute of Standards and Technology (NIST) and the Pacific Northwest National Laboratory (PNNL) are each creating quantitative databases containing the vapor-phase infrared spectra of pure chemicals. The digital databases have been created with both laboratory and remote-sensing applications in mind. A spectral resolution of approximate, equals 0.1 cm(-1) was selected to avoid degrading sharp spectral features, while also realizing that atmospheric broadening typically limits line widths to 0.1 cm(-1). Calculated positional (wave- number, cm(-1)) uncertainty is </=0.005 cm(-1), while the 1sigma statistical uncertainty in absorbance values is <2% for most compounds. The latter was achieved by measuring multiple (typically >/=9) path length-concentration burdens and fitting a weighted Beer's law plot to each wavenumber channel. The two databases include different classes of compounds and were compared using 12 samples. Though these 12 samples span a range of polarities, absorption strengths, and vapor pressures, the data agree to within experimental uncertainties with only one exception.

Calibration↗

Microsystems technology for remote monitoring and control in sustainable agricultural practices.

The future development of advanced sensor and microsystems technologies for use in agriculture is briefly discussed, within a general appraisal of the industrial requirements and the potential economic and ecological benefits to be derived from the employment of novel sensing systems in sustainable agricultural practices, such as precision farming. It is proposed that these technologies are potentially important monitoring tools for farmers and growers, and that a concerted programme of research and development is required to satisfy the future requirements of the agricultural industry.

Agriculture↗