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PubMedDate not supplied

The evaluation of sensory processing: a validity study using contrasting groups.

The purpose of this study was to examine the validity of a sensory history questionnaire using contrasting groups. Specifically, the goal was to identify items on the Evaluation of Sensory Processing that differentiate between parent ratings of children with sensory integrative dysfunction and parent ratings of typically developing children. Data were collected from 30 parents of children with sensory integrative dysfunction and 59 parents of typically developing children. Items were analyzed using a Wilcoxon signed rank test to detect the difference between the parent ratings for the 30 children with sensory integrative dysfunction and 30 of the typically developing children who were matched to the dysfunctional children on age, ethnicity, gender, geographic location, and socioeconomic status. Eighty-four of the 200 items significantly (p < .05) distinguished between parents' ratings of children with and without sensory integrative dysfunction.

Case-Control Studies↗

PubMed1998

Evaluation of a self-administered sensory testing tool to identify patients at risk of diabetes-related foot problems.

OBJECTIVE: To study the use of a self-administered sensory testing tool designed to identify individuals at risk for diabetes-related foot problems and determine the inter-rater reliability between patient and provider sensory evaluations. RESEARCH DESIGN AND METHODS: Nine centers in eight states with established foot prevention centers mailed 196 self-screening testing materials to randomly selected patients with diabetes scheduled for follow-up appointments. Patients were instructed to perform a sensory test using a 10-g nylon filament at specified sites on the foot and to complete a brief survey form before their appointment. During the follow-up appointment, providers retested patients using an identical sensory filament at the same sites and completed a provider survey. RESULTS: Of the patients, 145 kept their appointments and completed the self-screening materials. There were 141 patient and 137 provider surveys that indicated the instructions were clear and easy to use. Sixty-eight percent of the patients reported self-testing without the assistance of another person. Patient and provider sensory test findings disagreed (P = 0.0014) in 18 of 145 cases and fair inter-rater reliability was found (kappa = 0.73). Disagreement in sensory tests was related to patient age (P = 0.012). Sensory loss, previously undetected by providers, was found in 23 case subjects. CONCLUSIONS: Self-administered sensory tests provide patients an opportunity to share in the responsibility for preventing diabetes-related foot problems but should not replace routine foot evaluation by a provider.

Age Factors↗

PubMed2002

Thermotactile threshold testing for the evaluation of sensory nerve function in vibration-exposed patients and workers.

OBJECTIVES: The aim of the present study was to ascertain the usefulness of thermotactile testing under the measuring conditions clarified by our previous study in the evaluation of vibration-induced neuropathy. METHOD: Thermal (warm and cold) thresholds were examined on the index fingers of both hands of ten patients with hand-arm vibration syndrome, 36 workers exposed to hand-transmitted vibration, and ten healthy controls, using an aesthesiometer under the following measuring conditions: change rate of the applicator temperature was fixed at a rate of 1 degrees C/s; finger contact force on the applicator was kept at 0.5 N; and forearm was positioned on a support. Vibrotactile thresholds at 125 Hz and pain thresholds were also measured on the index fingers. RESULTS: Both warm and cold thresholds had more severely deteriorated in the patients than in the controls. Vibrotactile and pain thresholds were also increased in the patients. In the vibration-exposed workers, the neutral zone between the warm and cold threshold differed from in the controls. Thermotactile thresholds were likely to have deteriorated with advanced nerve impairment. Likelihood ratios of thermotactile testing were significantly high between the patients and the controls. For vibration-exposed workers with elevated vibrotactile and pain thresholds, the ratios were also significantly high, particularly in the neutral zone, though the accuracy tended to be lower than in the patients. Thermotactile thresholds appeared to be more closely correlated with pain thresholds than vibrotactile thresholds. CONCLUSIONS: Thermotactile threshold testing under the present measuring conditions can be useful for evaluating small sensory nerve fibre dysfunction in vibration-exposed subjects, and the neutral zone may be a sensitive indicator in vibration-exposed workers who may have slight or mild nerve impairments.

Adult↗

PubMed1996

Texture evaluations of cooked, diced broiler breast samples by sensory and mechanical methods.

The texture of cooked chicken breast is usually determined on intact pieces or strips that are representative of the muscle. Researchers emphasize the importance of uniformity of sample size and orientation of fibers to the shearing blades to ensure consistent data from instruments such as shear devices. For sensory evaluations, sample pieces of chicken breasts presented to panelists are often sized as single 2-cm2 or several 1-cm2 pieces. In this study, two sensory and two mechanical procedures were evaluated for efficacy in discerning texture differences in 1-cm2 pieces of cooked chicken. Three postmortem deboning times (2, 6, and 24 h) provided a texture quality spectrum. Sensory characteristics were evaluated by descriptive analysis trained panel (DA-TP) and by category scales-untrained panel (CS-UP). Twenty-gram breast portions of 1-cm2 pieces were evaluated using a multi-blade Allo-Kramer (AK) shear blade. Warner-Bratzler (WB) shear values of intact 1.9-cm-wide strips were also recorded. Discriminant analysis classification based on CS-UP gave higher error rates (probabilities of misclassification) than classification based on DA-TP. The CS-UP error rates were 0.36 (tender) and 0.65 (juiciness). The error rate of classification by DA-TP was 0.21. Error rates for classification by mechanical devices were 0.30 for WB and 0.21 for AK. Sample size is a consideration in texture evaluation protocols. Smaller sample pieces appear to mask differences in initial chew characteristics and in juiciness that are due to deboning time.

Adult↗

PubMed2004

Sodium lactate addition on the quality and shelf life of refrigerated sliced poultry sausage packaged in air or nitrogen atmosphere.

The aim of this study was to determine the effect of sodium lactate addition on shelf-life extension of sliced poultry sausage packaged both in air and nitrogen atmospheres and stored in refrigerated conditions. Basic chemical composition, pH, and malonaldehyde content were assayed and color measurement using the reflection method was carried out. Microbiological examination consisted of determination of total number of aerobic psychrotrophic bacteria and number of lactic acid bacteria. Sensory evaluation of products was performed. Microbiological and sensory quality of sliced poultry meat sausage was dependent on the addition during production of sodium lactate and the composition of gases (air or nitrogen) used in packaging. Slices of poultry sausage with 1% as well as 2% of sodium lactate maintained their initial quality of evaluated sensory attributes longer, irrespective of the applied gases. Sodium lactate inhibited growth of aerobic psychrotrophic bacteria and lactic acid bacteria during refrigerated storage. Sodium lactate also inhibited the formation of malonaldehyde in sliced poultry sausage during refrigerated storage. The effectiveness of this process depended on the concentration of sodium lactate addition. It was concluded that 1% as well as 2% addition of sodium lactate could extend the shelf life of sliced poultry sausage packaged in air atmosphere and stored at 5 to 7 degrees C by 3 or 4 times, respectively. Sliced poultry sausage treated with 2% sodium lactate packed in nitrogen had the longest (35-day) shelf life. This was a sevenfold increase in the shelf life of sliced poultry sausage compared with the control.

Air↗

PubMed2005

Scientific analysis of second-hand smoke by the tobacco industry, 1929-1972.

The 1972 U.S. surgeon general's report The Health Consequences of Smoking was the first to include a warning about exposure to second-hand smoke. Because the tobacco industry has a record of withholding the results of their research from the public, we searched the internal tobacco industry documents and compared internal industry research on second-hand smoke to what the industry published in the open scientific literature through 1972. We found chemical analyses, sensory evaluations, and discussions of sidestream cigarette smoke (the smoke emitted by the cigarette between puffs, the main component of second-hand smoke), beginning in 1929. American Tobacco Company research in the 1930s indicated that, compared with mainstream smoke, sidestream smoke was produced in larger quantities and contained, per cigarette, 2 times more nicotine and 12 times more ammonia. Research funded by the Tobacco Industry Research Committee in the 1950s revealed that sidestream smoke contained, per unit cigarette, higher concentrations of carcinogenic polycyclic aromatic hydrocarbons, per unit mass, including four times more 3,4 benzopyrene. In 1956 and 1957, respectively, Philip Morris and R. J. Reynolds also began to research sidestream smoke. In 1961, Philip Morris began to do sensory evaluation and modification of sidestream odor during product development. This sensory evaluation of sidestream smoke was the first biological testing of sidestream smoke by a tobacco company. Prior to the release of the 1972 U.S. surgeon general's report, the tobacco industry published the majority of its findings in the open scientific literature and does not appear to have perceived second-hand smoke as a threat to human health.

Disclosure↗

PubMed1995

Cereal and nut bars, nutritional quality and storage stability.

Six snack-type bars were manufactured, to contain oat and wheat germ and two different walnut levels, agglutinated with natural sweeteners and fats. Two bars also contained toasted amaranth with brown sugar cover and wheat extrudate, while two others, contained puffed instead of toasted amaranth. Water activity (Aw) and moisture were determined in the manufactured products. Quality and sensory evaluation and proximate analysis were carried out on the bars containing highest levels of walnuts (18%). The caloric contribution of the bars was computed by Atwater methods. The nutritional quality of the bars was determined by means of the Protein Efficiency Ratio (PER) and Net Protein Ratio (NPR), and the results were used to obtain relative PER and relative NPR. Samples of the latter bars were kept under accelerated storage for 15 days at 37 degrees C and analyzed every 5 days to determine their Aw, moisture, peroxide and sensory acceptability. The drying time for the cereal - and walnut - based bars was 45 min at 120 degrees C. All bars presented a good fiber supply and the CN1 bar, containing only oat, wheat germ and walnut, had the greatest protein content. In the sensory evaluation, the walnut level with the greatest preference was 18%. PER and NPR values of the bars did not differ significantly showing values approximately 86% that of the casein value. During storage, the moisture and Aw decreased in all the bars. Peroxides remained within the acceptable ranges; acceptability based on sensory evaluation remained best in the bar with toasted amaranth.(ABSTRACT TRUNCATED AT 250 WORDS)

Amaranthus↗

PubMed1980

[Storage stability of Guelders smoked sausage (Gelderse rookworst) containing 20 per cent mechanically processed pork (author's transl)].

'Gelderse rookworst' (Guelders smoked sausage) containing 20 per cent of mechanically processed pork was prepared. The reference product was formulated with 20 per cent of manually deboned pork derived from the same lot of bones. The products were stored for 0, 4 and 8 weeks at 12 degrees C and subjected to chemical analysis (fat oxidation) and sensory evaluation. The type of bones was varied by using ham bones and vertebrae. Bones were used in the fresh state and after six weeks' storage at -18 degrees C. The effect of sodium ascorbate and a blend of ascorbyl-palmitate and alpha-tocopherol on oxidative rancidity was studied in the products. The internal and external colour of the freshly prepared sausages containing mechanically processed pork were considered to be superior, whereas the taste was regarded as being inferior to the corresponding products prepared with manually deboned tissue. The products containing residual meat from vertebrae were considered to be superior to those containing residual meat from ham bones. Sensory evaluation of the products containing residual meat from frozen bones did not differ to any appreciable extent from that of products derived from fresh bones. Lipid oxidation measurements (peroxide numbers and p-anisidine values) did not show any marked increase during storage of the products. Sensory evaluation of the products stored for four weeks at 12 degrees C revealed inferior products in a number of cases; this number continued to increase after eight weeks. Sausages containing ascorbate usually received higher scores for taste and internal colour than did the corresponding products without ascorbate or containing the blend of antioxidants.

Animals↗

PubMed1999

Theory of Reasoned Action predicts milk consumption in women.

OBJECTIVE: To determine the factors influencing the consumption or avoidance of milk in women. SUBJECTS/SETTING: One hundred women completed food frequency questionnaires and a milk attitudes questionnaire framed within the Theory of Reasoned Action and performed sensory evaluations of different milk samples. STATISTICAL ANALYSES: Differences among milk types were assessed using 2-way analysis of variance and least-significant-difference mean comparison procedures. Correlation and multiple regression analyses, and standardized partial regression coefficients, were used to determine the contribution of each component of the model in predicting behavior. RESULTS: Mean age of the 100 subjects was 39 years (range = 20-70 years). Milk consumption among subjects was low; 23 subjects indicated that they seldom or never drank milk. Data from the dairy frequency questionnaire showed that the primary milk for 42%, 36%, 27%, and 18% of the milk drinkers was skim, 2%, 1%, and whole, respectively (subjects could indicate more than 1 type of milk consumed). The Theory of Reasoned Action indicated that health and familiarity belief items were most associated with attitudes toward milk consumption. Skim milk had significantly lower scores for taste and texture belief items than 1%, 2%, and whole milk (P < .05), yet more subjects reported that they drank skim milk (42%) than the other milk types. Sensory evaluation demonstrated that subjects linked whole milk significantly more than skim milk (P < .05). CONCLUSIONS/APPLICATIONS: Some people continue to consume skim milk for reasons other than beliefs about taste and texture or actual sensory preference. This study identifies important factors contributing to milk consumption such as beliefs, attitudes, and sensory evaluation, which can be used to develop a specific framework in which to examine other components of milk consumption behavior.

Adult↗

PubMed1995

[Sensory nerve conduction velocity determined by somatosensory evoked potentials in patients with hereditary motor and sensory neuropathy type I].

We evaluated sensory nerve conduction velocity (SCV) determined by somatosensory evoked potentials (SEPs) components in 2 cases of hereditary motor and sensory neuropathy whose sensory nerve action potentials (SNAPs) were not evoked. SEPs elicited by median or ulnar nerve stimulation at the wrist or elbow were recorded from 5 scalp electrodes with ear reference. In both cases, no parietal N20 or frontal P20 component was identified, but a clear parietal P27 component was noted. The onset latency of the P27 component elicited by wrist or elbow stimulation was identified as the point where the superimposed 5 waves diverged. Then, the SCV was obtained by dividing the distance between the wrist and elbow by the onset latency difference. Tibial SCV was also determined by a similar method in one patient. The SCVs of the median, ulnar and tibial nerves were markedly decreased but 10-30% faster than the motor nerve conduction velocities measured concomitantly. We showed that a multichannel scalp recording of SEPs makes it possible to determine the onset latencies of the cortical components. So, SEP testing should be applied to obtain the SCVs in patients whose SNAPs were unrecordable.

Adult↗

PubMed1995

Cutaneous innervation in sensory neuropathies: evaluation by skin biopsy.

OBJECTIVE: To use punch skin biopsies to evaluate the loss of intra-epidermal nerve fibers in sensory neuropathies. BACKGROUND: Previous assessments of epidermal nerve fibers have been constrained by relatively insensitive staining techniques and variability in quantification. METHODS: Punch skin biopsies were performed on the heel and leg of HIV-seronegative controls, HIV-seropositive individuals without neuropathy, and patients with sensory neuropathies, including HIV-seronegative and HIV-positive individuals. After formalin fixation, 50-microns free-floating sections were stained with a monoclonal antibody to neuron-specific ubiquitin hydrolase, PGP9.5. The number of intraepidermal fibers/mm in at least three sections from each patient was counted by one observer blinded to site and clinical status. RESULTS: Dermal and epidermal nerve fibers were readily identified and quantified. The immunostaining technique reliably demonstrated a dermal plexus of myelinated and unmyelinated fibers parallel to the surface of the skin. In the epidermis, unmyelinated fibers ascended vertically between the keratinocytes to reach the stratum corneum. The number of intra-epidermal fibers/mm in the distal leg (mean +/- SEM) was 17.84 +/- 3.03 in seven HIV-seronegative controls. Epidermal fiber number was significantly reduced (p = 0.01) in five HIV-infected patients with sensory neuropathies associated with didanosine or zalcitabine therapy (1.07 +/- 0.40) and in eight HIV-seronegative patients with sensory neuropathies (3.1 +/- 3.1). Four of five neurologically normal HIV-seropositive subjects had reduced numbers of epidermal fibers, suggesting a subclinical neuropathy. Serial biopsies in one individual demonstrated the evolution of degenerating epidermal fibers after development of zalcitabine-induced sensory neuropathy. CONCLUSION: Skin biopsies stained with the sensitive panaxonal marker anti-PGP9.5 demonstrated significant reduction in intraepidermal fibers in sensory neuropathies. This simple and repeatable technique is a reliable method for quantitation of small cutaneous sensory fibers. In addition, skin biopsies may be useful in assessing the course and spatial distribution of involvement in peripheral nerve disease.

Adult↗

PubMed2005

[Evaluation of sensory deficit of the inferior alveolar nerve after mandibular osteotomy].

INTRODUCTION: Injury of the inferior alveolar nerve (IAN) is one of the most common complications of mandibular osteotomy. The wide differences in results published to date led us to evaluate the incidence of sensorial disorders persisting for one year in a series of 40 patients. MATERIAL AND METHOD: This study included 40 patients aged 14-58 years. We studied subjective expression of sensorial disorders using a questionnaire with items for the different orofacial functions related to the IAN. We studied the clinical expression of these sensorial disorders by testing the three modes of exteroceptive sensitivity (tact, temperature, pain) in 25 patients. Four clinical tests appropriate for the area of the mental nerve. Somesthesic evoked potentials were recorded in 8 patients. RESULTS: 77% of the patients complained of altered skin sensitivity but a sensorial deficit was revealed by clinical tests in only 60%. Somesthesic evoked potentials were perturbed for 64% of the nerves with a clinical deficit and in 100% without a clinical deficit. DISCUSSION: There was a greater incidence of subjective complaints than objective nerve injury. Recoring somesthesic evoked potentials provides interesting information for the electrophysiological diagnosis of nerve injury. Indications could be widened for traumatic injury of the IAN, particularly to obtain medicolegal documentation.

Adolescent↗

PubMed1998

Computer-based bioassay for evaluation of sensory irritation of airborne chemicals and its limit of detection.

We expanded a previously described rule-based computerized method to recognize the sensory irritating effect of airborne chemicals. Using 2-chlorobenzylchloride (CBC) as a sensory irritant, characteristic modifications of the normal breathing pattern of exposed mice were evaluated by measuring the duration of braking (TB) after inspiration and the resulting decrease in breathing frequency. From the measurement of TB, each breath was then classified as normal (N) or sensory irritation (S). Using increasing exposure concentrations, the classification S increased from < or = 2% (equivalent to sham-exposure) to 100% within a narrow exposure concentration range. The potency of CBC was then evaluated by calculating the concentration necessary to produce 50% of the breaths classified as S, i.e., S50. This approach is easier to use than obtaining RD50 (decrease in respiratory frequency by 50%) when high exposure concentrations are difficult to achieve. Detection limits were also established for this bioassay and experiments were conducted to obtain a level of response just around these limits, in order to delineate the practicality of using this bioassay at low exposure concentrations. Using this approach, sensory irritation was the only effect induced by CBC at low exposure concentrations. However, bronchoconstriction and pulmonary irritation were superimposed on this effect at higher exposure concentrations.

Air Pollutants↗

PubMed1994

A new fibrin seal: functional evaluation of sensory regeneration following primary repair of peripheral nerves.

A new fibrin seal has recently been evaluated in terms of axonal regeneration; however morphological examination of the fibre composition of regenerated nerves may not necessarily provide functionally relevant information. This study therefore aims to evaluate the functional regenerated sensation, following peripheral nerve transection treated with fibrin seal (Tisseel-Duo, Immuno; Austria). The sural nerve-innervated skin of the rat hindfoot served as the target organ. Previously published results from animals following transection and suture served as controls. Ten 3-month-old female Sprague-Dawley rats were used. The sciatic nerve was divided and rejoined with fibrin seal. The rats were allowed unrestricted movement directly after surgery and allowed to survive for 3 months. Our observations show that the functional results of regenerated polymodal nociceptors and low-threshold mechanoreceptors show no statistical difference when compared with microsuture. This strengthens the early positive morphological impression of this new product. Further prospective studies in man are anticipated.

Animals↗

PubMed1998

Mismatch negativity and auditory sensory memory evaluation: a new faster paradigm.

A new faster paradigm to measure the duration of auditory sensory memory, as indexed by mismatch negativity (MMN) suppression to stimuli presented at increasing inter-stimulus intervals (ISI), is proposed. Trains of three stimuli were delivered at very short ISI (300 ms). The inter-train interval varied according to the memory probe interval (MPI) tested. Trains started randomly with a deviant or standard stimulus (50% each), with their event-related brain potentials subtracted to obtain the MMN. The new paradigm provided MMNs identical to the conventional one at MPIs of 0.4 and 4.0 s in young subjects, and revealed MMN suppression when the MPI was increased to 5.0 s in older subjects. The new paradigm estimates auditory sensory memory duration in one-third the time of conventional MMN.

Acoustic Stimulation↗

PubMed2002

The evaluation of skin friction using a frictional feel analyzer.

BACKGROUND/AIMS: Sensory evaluation is an important factor for cosmetic products. Several devices for the measurement of sensory properties have been developed in recent years. The objective here is to measure skin surface friction using these devices and examine the correlation with other physiological parameters in order to evaluate the potential of physical measurement of tactile sensation. METHODS: A KES-SE Frictional Analyzer, a commercial device for measurement of surface frictional characteristics, was used in this study. An arm holder was added to this device for measurement on the human forearm. The frictional coefficient (MIU) and its mean deviation (MMD) were used as the parameter to indicate surface friction. The moisture content in the stratum corneum was measured with a Corneometer CM825, the transepidermal water loss with a Tewameter TM210, the viscoelastic properties of the skin with a Cutometer SEM575 and the skin surface pattern by observing the negative replica using silicon rubber. RESULTS: The MIU was not influenced by load; however, it was increased due to water application on the skin. The relationship between MIU and the moisture content in the stratum comeum, between MMD and skin surface pattern and between MMD and viscosity of both normal human forearm skin and SDS (sodium dodecyl sulfate)-induced dry skin were confirmed by statistical analysis in a test on human subjects. There was also a correlation between either MIU or MMD and sensory evaluation in the morning after the application of moisturizing products. CONCLUSION: Human skin surface friction was measured by using a KES-SE Frictional Analyzer. Judging from the correlation between either MIU or MMD and sensory evaluation, we considered this instrumental analysis to be useful for evaluating the tactile impression of human skin.

Biophysics↗

PubMed1992

Hypoalgesic effect of EMLA and lidocaine gel applied on human oral mucosa: quantitative evaluation by sensory and pain thresholds to argon laser stimulation.

Sensory and pain thresholds to argon laser stimulation were used to evaluate the analgesic efficacy and duration of a eutectic mixture of local anesthetics (EMLA) and a 2% lidocaine gel applied topically on the oral mucosa. Application of EMLA for 2 min on the tongue and gingiva increased the pain thresholds by 92.8% and 63.4% respectively. Corresponding values for lidocaine gel were 53.6% and 21.9%. Standardized variation of the EMLA application period (2, 5, and 15 min) produced significantly different analgesic profiles on the tongue but not on the gingiva. Application of EMLA for 5 and 15 min on the tongue and for 2, 5, and 15 min on the gingiva increased the pain thresholds to a predefined analgesic level (2.15 W) for 2 to 25 min. The present experimental model for assessment of oral mucosa pain is suggested to be well-suited for investigations of intraoral analgesia.

Administration, Topical↗

PubMed1985

Evaluation of sensory nerve conduction velocity testing of the superficial radial nerve.

The purposes of this study were to evaluate the methods for examining the superficial radial nerve and to compare velocities and amplitudes of responses based on electrode shape and placement and site of stimulation. We selected 51 subjects with a mean age of 37 years from a healthy group. Twenty additional subjects with a mean age of 28 were also examined. Nerve conduction was done by stimulating over the dorsal forearm and lateral arm and recording from the superficial radial nerve where its branches cross the extensor pollicis longus tendon. The second group of subjects were stimulated at the same site and also at the elbow. Recording was done with a rectangular-shaped electrode placed in the area between the extensor pollicis longus and the extensor pollicis brevis tendons. We found a mean conduction velocity of 61 m/sec +/- 4.91 in the first group with a mean amplitude of response of 36.7 microV +/- 11.7 when we stimulated at the forearm site and 4.06 microV +/- 6.75 when we stimulated at the lateral arm site. In the second group of subjects, conduction velocity from lateral arm to forearm site was 63 m/sec +/- 4.50; from the lateral arm to elbow, 66 m/sec +/- 10.4; and from the elbow to the forearm site, 64 m/sec +/- 9.71. Amplitudes of response were 43.8 microV +/- 14.45 at the forearm stimulation site, 18.06 +/- microV +/- 7.37 at the elbow site, and 6.7 microV +/- 4.25 at the lateral arm site. We compared the mean velocities from the two methods and found no significant differences.(ABSTRACT TRUNCATED AT 250 WORDS)

Adolescent↗