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Results for “Calcification, Physiologic”

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At least 145 records · Page 8Linked to original sources
PubMed1965

TETRACYCLINE: EFFECT ON OSTEOGENESIS IN VITRO.

Tetracycline hydrochloride added to cultures of rudiments of embryonic bone in a concentration of 1 microgram per milliliter prevents mineralization of the bones and is found throughout the calcified zones. The inhibition is reversible; upon transfer of a treated culture to a normal medium, mineralization proceeds normally but maldeveloped bones result.

Animals↗
PubMed1988

Diffuse idiopathic skeletal hyperostosis.

The ubiquitous nature of spinal ligamentous calcification in the paleontologic record provides additional support for the suggestion that DISH is a protective phenomenon rather than a musculoskeletal disease, and perhaps represents a normal variant. Clinical assessment of contemporary DISH suggests a protective mechanical effect, paradoxically associated with increased risk of hypertension and cerebrovascular accident. DISH should probably not be considered a satisfactory explanation for back pain, but the presence of spinal ligamentous calcification requires that the patient be assessed for hypertension and that aggressive therapy be instituted for any found.

Adaptation, Physiological↗
PubMed1965

SOME ASPECTS OF CALCIUM METABOLISM IN MALIGNANT DISEASE OF BONE.

The rate of calcification of new bone (accretion rate) was measured by a radioisotope technique in 20 patients with carcinoma of the breast, 14 patients with multiple myelomatosis, five patients with Paget's disease of bone, and in six patients with solitary, non-osseous tumours. The rate of bone destruction was assessed in these patients by the measurement of the rate of urinary calcium excretion. In the patients with carcinoma of the breast and bone metastases there was a marked increase both in the accretion rate and in the urinary calcium excretion suggesting an osteoblastic response to bone destruction. An osteoblastic response was also present in the patients with multiple myelomatosis but was not correlated with the urinary calcium excretion. In patients with Paget's disease of bone, high values of accretion rate were found indicating very active new bone formation.

Bone Neoplasms↗