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At least 19 recordsLinked to original sources
PubMed1977

[Automated evaluation and analysis of isotopic heart function tests with minimal cardiac transit times].

The clinical evaluation of cardiac function by non-invasive means with the help of radioactive isotopes registering minimal cardiac transit times (MTTs) is increasingly employed in routine diagnosis. In order to economise on work load and time expenditure and for the purpose of an objective and complete evaluation of data, automatic data processing is desirable. This paper describes a program that consists of 4 sections: 1. examination 2. generation of data 3. processing of data 4. evaluation of data. The program permits a nearly total automated data generation, analysis, calculation, classification, final clinical evaluation and the automated production of a medical report. This greatly reduces the time spent per examination to approximately 5 minutes. The automated evaluation of the data is based on clinical experience with approximately 3.500 measurements in patients with the most frequent cardiac diseases. The result is an objective statement of causes of MTT changes and is highly useful for medical routine application. The control and the final inclusion of the findings into the spectrum of other clinical results remains the subject of the physician's judgement. The advantage of the method is the evaluation of all cardiac segments. This pertains to the evaluation of both atria and both ventricles, as well as of the entire central circulation with and without participation of the lung.

Computers↗
PubMed1991

[Arrhythmic syncope and invasive electrophysiologic heart function tests].

The authors submitted to electrophysiological examination a total of 100 patients (66 men and 34 women) with brief disorders of consciousness where they ruled out extracardiac causes of unconsciousness, impaired blood flow through the heart and the syndrome of s-a node dysfunction. Forty-three subjects had severe arrhythmias during ECG monitoring in bed or by Holter's system (20 subjects paroxysms of ventricular tachycardia, 14 subjects ventricular extrasystoles according to Lown class 3-5, six subjects had transient high-grade a-v blocks, three subjects had symptomatic paroxysms of supraventricular tachycardia). In 57 patients ECG monitoring did not reveal ectopic arrhythmias and high-grade a-v blocks. Invasive examination confirmed or diagnosed arrhythmic syncopes in 49% of the entire group of 100 patients. It assessed the arrhythmic cause of syncopes in 33% of 57 subjects without severe arrhythmias and in 70% of 43 subjects with severe arrhythmias detected during ECG monitoring.

Adolescent↗
PubMed1979

[Index of isometric contraction--a comparison with invasive methods of cardiac function testing in patients with ischemic heart diseases and post-myocardial infarct status].

In 81 patients with an ischaemic heart disease and myocardial infarction the evidence of the presphygmic index PI (non-invasive index) was tested concerning a beginning myocardial functional disturbance and a latent heart insufficiency, respectively, with the help of an invasive cardiopulmonary functional diagnostics which was performed under dosed bicycle ergometer load in the steady state. The presphygmic index PI correlates in significantly positive way with the end-diastolic pressure of the heart and the quotient from minute volume of the heart and the end-diastolic pressure of the pulmonary arteries (VM/PAEDP). The presphygmic index is on the basis of this correlation of the left-ventricular function suitable to establish disturbances of the myocardial functions and to give the possibility of a separation of the patients in cardially sufficient and cardially insufficient ones. Here the evidence of the presphygmic index might be larger concerning the recognition of a latent heart insufficiency than concerning the recognition of beginning myocardial functional disturbances. The presphygmic index apparantly possesses a high degree of sensibility then, when the myocardial functional disturbances coincide with a beginning reduction of the pumping action of the heart.

Adult↗
PubMed1986

Age-related changes in left ventricular diastolic performance.

Previous studies show that the radionuclide-derived indices of left ventricular (LV) diastolic performance are abnormal at rest in many patients with coronary artery disease (CAD), even in those with normal resting ejection fraction (EF) and no prior myocardial infarction. This study examined the age-related changes in LV peak filling rate and time to peak filling rate in 65 subjects between the ages of 20 and 75 years with a low likelihood of CAD. All subjects had normal resting EF (greater than or equal to 50%), and none had prior infarction. There was a significant age-related decline in resting peak filling rate (r = -0.47, p less than 0.001) and exercise peak filling rate (r = -0.52, p less than 0.001), but no age-related effect in the time to peak filling rate. Of the 29 subjects less than 50 years of age, 26 (90%) had resting peak filling rate greater than or equal to 2.5 EDV/sec (3.1 +/- 0.6, mean +/- SD) compared to 17 of 36 subjects (47%) greater than or equal to 50 years of age (2.6 +/- 0.6) (p = 0.002). In a subgroup of 28 subjects with a history of hypertension, the age-related effect was more marked than in the remaining 37 subjects without such a history (r = -0.66 vs -0.33). Thus, the peak filling rate at rest and during exercise decreases with advancing age; the high frequency of observed abnormality in the peak filling rate at rest in patients with CAD may conceivably be related in part to age differences between patients with CAD and the control group.

Adult↗
PubMed1977

Left ventricular function after cigarette smoking by chronic smokers: comparison of normal subjects and patients with coronary artery disease.

Twenty normal subjects and 25 patients with coronary artery disease underwent systolic time interval analysis before and after rapidly smoking two cigarettes. A slight increase in heart rate and arterial pressure was seen in both groups. In patients with coronary artery disease, preejection period/left ventricular ejection time ratio increased; in normal subjects it decreased. Left ventricular performance is diminished after cigarette smoking among subjects who have preexisting significant coronary artery disease.

Adult↗
PubMed1989

Specialized testing after recent acute myocardial infarction.

A wide variety of specialized laboratory tests have been used to characterize prognosis and functional capacity soon after a patient has an acute myocardial infarction. Few attempts have been made to integrate the available data on these tests into clinically relevant guidelines for the clinician. This review evaluates the use of these tests, alone and in combination, throughout the course of recovery from acute myocardial infarction. The primary objective of these tests is to quantify myocardial ischemia and left ventricular dysfunction, the pathophysiologic basis of prognosis and functional capacity. The selection of one test over another depends on whether either test provides information on myocardial ischemia and left ventricular dysfunction not available through the standard clinical evaluation, and the risk, quality, and cost associated with each test. The stepwise application of specialized testing after acute myocardial infarction enables the identification of three groups of patients: approximately 20% at very high risk, due primarily to irreversible left ventricular dysfunction; approximately 30% at moderately high risk, due primarily to myocardial ischemia; and approximately 50% at low risk who are free of significant left ventricular dysfunction or myocardial ischemia. Accurate discrimination among these three groups enables the application of aggressive medical and surgical therapy to patients at moderate to high risk and accelerated recovery for patients at low risk. Specialized testing also helps to guide subsequent management after thrombolysis and revascularization procedures.

Coronary Angiography↗