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Results for “Satiation”

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At least 19 recordsLinked to original sources

PubMed1979

A food satiation and oral hygiene punishment program to suppress chronic rumination by retarded persons.

Food satiation and oral hygiene punishment were used to treat the non-life-threatening rumination of two institutionalized profoundly retarded persons. Satiation consisted of allowing the clients to eat until a satiation criterion of food refusal was achieved or until two full meal portions were consumed. The oral hygiene procedure consisted of cleansing the clients' teeth and gums with Listerine for 2 minutes following each instance of rumination. In the formal study, three conditions--baseline, satiation, and satiation plus oral hygiene--were used following the lunch meal in a multiple-baseline across-subjects design. One client's rumination decreased from an average of 89.5% during baseline to 48.8% during the satiation condition and to 3% during satiation plus oral hygiene. The second client's rumination decreased from a baseline average of 49.9% to 7.9% during satiation and to 1.4% during satiation plus oral hygiene. Generalization probes taken following the breakfast and dinner meals showed a systematic decline in rumination as the various conditions were implemented following the lung meal. In the 16-week follow-up, rumination was treated following all meals with oral hygiene, and satiation was used at one of the daily meals for 1 week on a rotating basis. Rumination remained at a near-zero level following all meals throughout the follow-up. Thereafter, a maintenance program was conducted by the ward staff. The satiation plus oral hygiene punishment treatment program appears to be an immediate, effective, enduring, and humane method of treating the non-life-threatening rumination of retarded individuals.

Adult↗

PubMed1992

The threshold for satiating effectiveness of psyllium in a nutrient base.

A combination of psyllium fiber with nutrients in a commercially available wafer (Fiberall-Ciba Consumer Pharmaceutical) was evaluated for its effectiveness in reducing food intake and appetite. Each of 15 nonobese healthy women received no wafers and four different amounts (39, 104, 169, and 234 kcal) of the fiber wafer with water, in a ratio of 13 kcal (and 0.565 g psyllium) wafer per 41.67 g water, 30 minutes prior to a test meal of macaroni and beef, on nonconsecutive days. Intake of the test meal and hunger ratings were both significantly reduced after intake of the two largest wafer amounts (169 and 234 kcal, respectively), in comparison with the two smaller amounts and none at all. The reduction produced by the largest amount compared to none at all was 122 kcal (about half the energy of the amount given). There were no significant differences in intake and hunger ratings among the two smaller amounts and none at all. Thus the threshold for intake reduction by this product with water lies between 104 and 169 kcal. Methodologically, this work underscores the importance of testing the satiating effects of foods at multiple levels before conclusions are drawn about their satiating effectiveness, and suggests that the threshold for significant reduction should be considered as a measure of the product's satiating effectiveness. The relative contributions of the nutrients, the fiber, and the water to the satiating effect still need to be determined.

Adolescent↗

PubMed1992

Beliefs about the satiating effect of bread with spread varying in macronutrient content.

Beliefs about the satiating effect of foods varying in contents of proteins, fats, carbohydrates, and fibre were investigated by face-to-face interviews with a random telephone sample of 101 subjects. Respondents were presented with photographs of two slices of bread covered with common spreads. Fibre level was manipulated by using white bread or wholemeal bread. Levels of proteins, fats and carbohydrates were manipulated by using different kinds of spread. Low and high levels of proteins, fats and carbohydrates had similar energy contents. The results showed that protein-rich spreads (lean meat products) and high-fibre (wholemeal) bread were believed to have a strong satiating effect. The satiating effect of high-fat spreads (butter, bacon) was believed to be much smaller, whereas the sweet carbohydrate spreads (jam, honey) were believed to have no satiating effect.

Adult↗

PubMed1978

A smoking satiation procedure with reduced medical risk.

Tested the efficacy of a smoking satiation procedure with reduced medical risk. As predicted, experimental taste satiation (holding smoke in the mouth with occasional inhalations) suppressed habitual smoking as effectively as rapid smoking satiation. In view of the extensive relapse problems that follow the singular application of aversive conditioning procedures, follow-up hypnosis and counseling treatments were applied in order to assist Ss in maintaining smoking cessation. At the time of the 6-month follow-up contact, confirmed abstinence reports for 66% of all Ss who received treatment were obtained.

Adult↗

PubMed1976

Necker cube reversal: sensory or psychological satiation?

24 students, 5 male and 19 female, were used in a repeated-measures factorial design to test two theories of Necker cube reversal. It was hypothesized that cubes with complete contours and high figure-ground contrast would reverse at faster rates than cubes with incomplete contours and low contrast if a sensory satiation theory (Köhler & Wallach, 1944) is valid, but at the same rate if the satiation of an orientation theory (Orbach, Ehrlich, & Health, 1963) is correct. High contrast was achieved with black contours on white grounds and vice versa, low contrast with gray contours on black and white grounds. Cubes with complete contours, and stimuli in which only the eight corners of the cube were visible through 18-mm holes superimposed upon the complete cube, provided the contour variable. The results showed a higher reversal rate for cubes with complete contours but no contrast effect. The results were interpreted as supporting a sensory satiation theory.

Adaptation, Ocular↗

PubMed1975

Food satiation as a procedure to decelerate vomiting.

A food satiation procedure was used in two experiments to decelerate the frequency of vomiting responses in two profoundly retarded adults who exhibited well-defined vomiting-ruminatory response chains. For several years prior to this study, the subjects had exhibited a history of vomiting behavior. Satiation was accomplished during regular meals and consisted of allowing the subjects to eat until a satiation criterion of food refusal was achieved. The results revealed a 94 percent reduction of vomiting in Experiment 1 and a 50 percent response reduction in Experiment 2. Ten-day follow-up sessions indicated that the response reduction was maintained in both experiments. In Experiment 1 the subject exhibited a 4.99 kg weight gain at the 10-day follow-up with a total of 13.61 kg weight gain at a 4-week posttreatment weight check.

Feeding Behavior↗

PubMed1975

Pattern of drinking and feeding produced by hypothalamic norepinephrine injection in the satiated rat.

Injection of norepinephrine into the perifornical region of the anterior hypothalamus elicited both drinking and feeding in satiated rats. Analysis of these behaviors revealed the following: (1) Both responses were dose-dependent, occurring at doses at least as low as 0.5 mug. (2) The drinking response (1-4 ml) had a latency of around 1.5 min and a duration of 2-3 min. It was followed within a minute or two by eating (2-4 g) that lasted approximately 20 min. It was also followed by a period of drinking suppression that lasted approximately 60 min. (3) Satiation from the ingestion process appeared to be a primary factor in terminating the elicited feeding response, whereas a time-related factor was important in terminating the elicited drinking. (4) These ingestive responses produced by noradrenergic stimulation of the anterior perifornical hypothalamus were found to bear striking similarities to the rat's natural feeding behavior and premeal component of his natural food-associated drinking behavior. (5) These noradrenergically elicited responses could not be observed with lateral hypothalamic stimulation, while only feeding was elicited by ventromedial hypothalamic stimulation. (6) The drinking induced by central noradrenergic stimulation, in contrast to that induced by peripheral beta-adrenergic stimulation, was unaffected by nephrectomy.

Animals↗

PubMed1977

Satiation and sensory deprivation combined in smoking therapy: some case studies and unexpected side-effects.

Two promising techniques for smoking reduction, sensory deprivation and stimulus satiation, were applied in combination to five smokers. All were successful initially in achieving abstinence and four ultimately in maintaning abstinence. The issue of possible side-effects is worth considering. Quitting per se and both satiation and sensory deprivation may be stressful and as a result may potentially produce negative side effects. The observation of positive side-effects in these cases balances this possibility to some extent.

Adult↗

PubMed1992

GABAA receptors in the amygdala: role in feeding in fasted and satiated rats.

The purpose of this study was to clarify further the site of action in the amygdala as well as functional characteristics of feeding in response to two GABA receptor agonists. Guide cannulae for microinjection were implanted stereotaxically in the rat just above the central nucleus of the amygdala (CNA). Microinjections of 0.05, 0.25, 0.5 or 1.0 nmol muscimol, a GABAA-selective receptor agonist, produced a dose- and time-dependent decrease of food intake in both the satiated and fasted rat. The bilateral injection of muscimol into the amygdala was more effective than a unilateral injection during the first 2 h, although the overall effects were similar. Microinjection of 0.1 nmol bicuculline methiodide, a GABAA receptor antagonist, into the CNA significantly blocked this inhibitory effect of 0.05 and 0.5 nmol muscimol again in both the satiated and fasted rat. Doses of 0.05, 0.5, 5.0 and 10.0 nmol of the selective GABAB agonist, baclofen, injected into homologous sites in the CNA did not alter food intake. These findings support the viewpoint that the amygdala and its central nucleus comprise a pivotal region involved in the mechanisms underlying the control of feeding behavior. Further, it is envisaged that hypophagic or anorexic responses are induced through the activation of GABAA receptors by the presynaptic release of GABA from neurons which form a component of the anatomical system for hunger and satiety.

Amygdala↗

PubMed1992

Maltose: the primary signal of hunger and satiation in human beings.

In rats, blood glucose concentration serves as the primary signal responsible for the induction of the sensation of hunger. In human beings, however, blood glucose concentration has been shown not to be the primary signal for the production of hunger sensation. Disaccharide, in the form of lactose in milk, sucrose in nature, and maltose from the breakdown of starch in the mouth, is part and parcel of human diet. The present study tested the hypothesis that maltose could be the primary signal responsible for the induction of the sensation of hunger and satiation in human beings. The hunger-moderating effect of maltose was compared with that of glucose by applying the test materials to the sweet-sensing taste buds on the tongue. Even at lower dosages, the effect of maltose was significant. At higher dosages, both glucose and maltose caused significant moderation of hunger. Maltose, a disaccharide, can be the agent responsible for the primary signals to induce the sensations of hunger and satiation in human beings.

Adult↗

PubMed1992

The 5-HT1A agonist 8-OH-DPAT attenuates the satiating action of cholecystokinin.

To investigate the dependence of the satiating action of cholecystokinin (CCK) on serotonergic action at central 5-HT receptors, we examined the effect of systemic pretreatment with 8-OH-DPAT (a 5-HT1A agonist that decreases central 5-HT synthesis and release via an action at somatodendritic autoreceptors in the brainstem raphe) on the suppression of food intake induced by systemic administration of cholecystokinin octapeptide (CKK-8). 8-OH-DPAT significantly attenuated the satiating action of CKK-8. This result is consistent with the hypothesis that peripherally acting CCK recruits central serotonergic processes to elicit normal satiety.

8-Hydroxy-2-(di-n-propylamino)tetralin↗

PubMed1992

Effects of methadone on free feeding in satiated rats.

A variety of opioids and opiates are known to increase short-term food intake. In the present study, we evaluated the effects of methadone on free feeding in satiated rats. We assessed the effect of methadone (0, 1.5, 3.0, 5.0, and 10.0 mg/kg) on food intake 1, 2, 4, and 6 h after injection for 3 consecutive days. Two hours after methadone administration, food intake was inversely related to dose, but after 6 h a direct relationship between dose and feeding was obtained. Food intake increased with repeated methadone administration. In Experiment 2, methadone (5.0 mg/kg) was injected and food was made available 0, 1, 2, or 3 h later. Maximal food intake occurred in the third and fourth hours following methadone administration. As in Experiment 1, food intake increased with repeated methadone administration. Increases in food intake following repeated methadone administration may have been due to the development of tolerance to effects of methadone that may interfere with feeding, such as sedation. In Experiment 3, methadone was administered daily or every fifth day, assuming that spacing injections would retard tolerance development. Repeated daily methadone administration was associated with increased food intake earlier in the session, whereas increases in food intake following spaced methadone administration occurred later in the session. These data indicate that methadone increases short-term feeding in satiated rats. This is in contrast to the reported decrease in food-reinforced behavior noted in operant studies. This contrast may be due to sedating or other disabling effects of methadone.

Animals↗

PubMed1979

Satiation therapy: a procedure for reducing deviant sexual arousal.

Two single-case experiments demonstrated the efficacy of satiation therapy with adult males who had long-standing deviant sexual interests. The procedure involves the pairing of prolonged masturbation (1 hour) with the verbalization by the patient of his deviant sexual fantasies and in both cases the designs permitted the attribution of control over aberrant responding to the satiation therapy. The results are discussed in terms of the possible active ingredients of the procedure.

Adult↗

PubMed1976

The effects of (+)-amphetamine and fenfluramine on feeding in starved and satiated mice.

(+)-Amphetamine and fenfluramine depressed both the food intake during the first 2 h of feeding of mice adapted to feed between 12:00 and 15:00 daily and the food intake of free feeding mice between 24:00 and 02:00 (lighting on, 09:00-21:00) in a dose-dependent manner. Higher doses of each drug were needed to produce a significant depression in the latter case. However, (+)-amphetamine (0.5-2 mg/kg) markedly increased the negligible food intake of free feeding mice between 12:00 and 14:00, an effect which rapidly disappeared at higher doses. Fenfluramine at doses up to 40 mg/kg had no effect on the feeding of these mice. Nevertheless, as caffeine (10-40 mg/kg) also increased feeding, behavioural arousal might be an important factor in this anomalous feeding response, although a specific action by (+)-amphetamine and caffeine on the feeding centres of the satiated mouse cannot be ruled out.

Amphetamine↗

PubMed1975

Ingestion in the satiated rat: role of alpha and beta receptors in mediating effects of hypothalamic adrenergic stimulation.

Anterior perifornical hypothalamic injection of l-norepinephrine in satiated rats elicits a brief, vigorous drinking response followed within a minute or two by a vigorous feeding response. These adrenergically elicited responses, which bear striking similarities to a rat's naturally motivated ingestive behaviors, were examined in the present series of experiments. It was found that: (1) Both responses could be elicited by perifornical hypothalamic injection of l-epinephrine, which was actually found to be more potent than l-norepinephrine. In contrast, only feeding could be elicited by the alpha-stimulant metaraminol, and neither feeding nor drinking could be elicited by hypothalamic injection of d-norepinephrine. l-isoproterenol, or dopamine. (2) The threshold doses of l-epinephrine for eliciting reliable ingestive responses were quite low, namely, 0.8 nmole (0.15 mug) for drinking and 0.2 nmole (0.04 mug) for feeding. (3) Pharmacological analysis of the ingestive behaviors induced by l-norepinephrine or l-epinephrine indicated that the eating response was mediated by alpha-adrenergic receptors, whereas the drinking response involved the synergistic action of both alpha- and beta-adrenergic receptors. No evidence for the involvement of dopaminergic or cholinergic (muscarinic) receptors was obtained. (4) A third adrenergically elicited phenomenon, namely, a suppression of drinking, was observed during and after the period of induced feeding. Analysis of this effect revealed its dependence solely upon alpha-adrenergic receptor activity.

Animals↗

PubMed1977

Comparison of the cycloheximide and food satiation effects on a discrimination task.

The effects of intraventricular cycloheximide (CHX) pretreatment were examined on the ability of rats to recall a light position discrimination task. The CHX pretreatment used inhibited brain protein synthesis at the time of training by 71%. Following treatment with CHX the animals demonstrated no retention of the task 18 hr later. Free feeding for 24 hr prior to treatment with cerebro-spinal-like fluid (CSF) produced similar effects as CHX. It is proposed that the amnesic effect of CHX in this behavioral paradigm may be a nonspecific action resulting from decreased motivation. Both the CHX-treated and satiated animals exhibited low responding levels during training, despite comparable behavioral activity levels for the CHX- and CSF-treated groups.

Animals↗

PubMed1979

Increasing the rate of ethanol consumption in food- and water-satiated rats.

The effects of food satiation, ethanol concentration, and the schedule of ethanol availability on the rate of ethanol consumption were investigated in rats. In Experiment 1 separate groups were exposed to 6.2 or 12.5% w/v ethanol and unlimited access to food. The food and ethanol were available concurrently for one to three hours daily. After approximately 15 sessions unlimited food was available whenever ethanol was not available. The rate of ethanol consumption was positively related to ethanol concentration and negatively related to duration of ethanol availability. In Experiment 2 similar procedures were followed, except rats had unlimited access to food throughout the experiment. The results were similar to Experiment 1. In Experiment 3 separate groups were exposed to 6.2 and 12.5% w/v ethanol for one hour every other day; unlimited food was available throughout the experiment. The results were similar to the one-hour availability groups in Experiments 1 and 2. In all experiments ethanol consumption rates increased to levels above baseline and above the usual ethanol metabolic rate found in rats. The results demonstrated new combinations of ethanol availability and non-availability durations that were sufficient to significantly increase the rate of ethanol consumption.

Alcohol Drinking↗

PubMed1979

A first order approximation of satiation time: (IRT)2/Rt.

Habituation, satiation, adaptation, and boredom are a few of the words used to label the behavioral consequences of a fundamental operation: repeated and protracted presentation of a stimulus. The cumulative measure of the response associated with that stimulus is expected to display an inflection at some time Ti after which the slope approaches zero. Ti can be estimated by dividing the square of the interresponse time (IRT)2 by the duration of the response associated with reinforcement (Rt), where Rt is expressed in the nearest whole temporal unit of interresponse time. Calculated TiS for habituation to the same sexual, aggressive, or social stimuli are compatible with general observation.

Habituation, Psychophysiologic↗