PubMed Health⌕ Search

SEARCH · PubMed Health

Results for “Stomatitis, Denture”

Explore indexed PubMed citations for clinical trials, systematic reviews and public health research. Read source abstracts and follow each citation to its original PubMed record.

Quote a phrase for an exact phrase match. Source license links do not imply unrestricted reuse.

At least 19 recordsLinked to original sources
PubMed1979

The role of C. albicans in denture stomatitis.

Denture stomatitis is an erythematous disorder of the denture-bearing tissues, especially the maxillary hard palate. Frequently it mimics many oral lesions. Early diagnosis of the lesion is essential to assure rational therapy. A diagnostic procedure based upon the enumeration of Candida albicans appeared to be feasible. A control group of twenty fully dentate subjects with no clinical evidence of stomatitis was sampled to establish normal concentrations of C. albicans in the oral flora. Samples were taken from a triangular area of the hard palate, serially diluted in broth, and all dilutions were incubated aerobically. In the control population, C. albicans never exceeded 100 organisms per square centimeter per subject sample. A population of edentulous patients with denture stomatitis, prior to any therapy, was similarly sampled. In many of these patients the concentration of C. albicans always exceeded 10,000 organisms per square centimeter per patient. The patients received denture replacements and antimycotic antibiotic therapy. Follow-up cultures were taken 4 to 6 weeks after completion of therapy. All patients were found to be free of denture stomatitis.

Antifungal Agents↗
PubMed1975

Denture stomatitis. A clinical, electron-microscopic, microradiographic and light-microscopic study.

The present study includes a reexamination of 10 patients who, two years ago received complete upper and lower denture treatment to eliminate an existing denture stomatitis. Clinical healing of the denture stomatitis was obtained only in one patient, whereas the remaining nine patients wtill displayed an obvious denture stomatitis. Biopsies were taken from the palatal mucosa and examined histologically, microradiographically, and by electron microscopy. The results of these examination indicated that, in denture stomatitis there is a reduced thickness of the epithelium, an absence of a stratum corneum, a markedly widened intercellular space, especially in the stratum basale, and an intense infiltration of inflammatory cells, plasma cells and lymphocytes in the connective tissue, as well as in the epithelium. These changes are characteristic features of an inflammatory process, and similar to the changes which occur, for example, in chronic, marginal gingivitis. The composition of the inflammatory infiltrate suggested that, in denture stomatitis, immunological phenomena influence the pattern of the tissue reaction.

Alveolar Process↗
PubMed1976

[Clinical evaluation of an hygiene program for patients with denture stomatitis].

1. Daily thorough cleaning of dentures is the essential factor for the healing or prevention of denture stomatitis. 2. The denture-bearing base and its mucosal side should be shaped and prepared in such a manner that denture hygiene is facilitated. 3. In papillomatous stomatitis surgical and hygienic measures must be combined.

Dentures↗
PubMed1977

Denture stomatitis and methods influencing its cure.

A review of the etiology and pathology of chronic denture stomatitis is presented, and two current methods of treatment have been evaluated. The concept of use of tissue conditioning materials is discussed and has proved to be helpful. The physical condition of the patient and his cooperation during and after treatment were observed to be significant factors in the treatment of chronic denture stomatitis. This study was preliminary in nature. Before more conclusive judgements can be made, standard methods should be developed for quantifying the improvement for patients with chronic denture stomatitis. In a more comprehensive study, steps could be taken to guard against investigator bias.

Denture Liners↗
PubMed1976

Evaluation of a dehydrated test strip,Microstix -Candida for detection of Candida-induced denture stomatitis.

The outgrowth of yeast from the fitting surface of the maxillary denture and the palatal mucosa was estimated in 63 denture wearers by means of smears and by culture on Microstix-Candida (M-C). There was a significant relationship between the concentration of yeasts as assessed by smears and by M-C. There were confluent spots on M-C, indicating large numbers of yeast cells, in 81% of 37 denture wearers with a positive microscopic diagnosis for Candida-induced denture stomatitis, whereas there were confluent spots on M-C in only one of 26 denture wearers with a negative microscopic diagnosis for infection. It is concluded that the M-C test seems to have sufficient diagnostic sensitivity to be an alternative to the smear for establishing the diagnosis of Candida-induced denture stomatitis.

Candidiasis, Oral↗
PubMed1975

Denture stomatitis. Relapse tendency and removal of acquired discolourations in long-term denture disinfection with chlorhexidine.

Five patients with denture stomatitis were initially treated for 14 days with a combination of amphotericin B lozenges and denture soaking in 0.2% chlorhexidine. To prevent recurrence the dentures were then kept overnight in 0.2% chlorhexidine during five months. No relapse occurred, but the dentures (all-acrylic) became heavily discoloured by chlorhexidine. During this period fungi could not be grown either on palatal or on maxillar denture agar models, and clinical signs and symptoms were reduced further. At the end of treatment hypochlorite was used to remove chlorhexidine-induced denture stain. Brushing and soaking (0.16%) proved more efficient than brushing alone, and when a 0.60% solution was used, the stains were generally eliminated in two hours. Hypochlorites in the prevention and removal of chlorhexidine discolourations deserve further attention.

Aged↗
PubMed1978

Experimental Candida-induced denture stomatitis in the Wistar rat.

An experimental model of yeast-induced denture stomatitis has been set up in the rat by inoculating Candida albicans on the fitting side of a maxillary acrylic plate retained by an orthodontic band around the incisors. Thirty-eight Wistar rats were used in two series of experiments with an observation period of 2 weeks. In each of the series there were one control and three experimental groups. Control rats were left untreated, while rats of the experimental groups wore either uninoculated or inoculated plates, or had their palatal mucosa smeared with the yeast. For cytologic examination the palate was scraped in Series I and the fitting side of the plate in Series II. After 1 week a generalized simple inflammation had developed in the palate of most animals of the experimental groups. It was most severe and persistent in rats with inoculated plates. Histologic signs of inflammation and hyphal formation were also most pronounced in this group. Hyphae did not invade the epithelium. Except for an initial loss of body weight, which was restored by day 10 or 12, the rats tolerated their plates. The Wistar rat seems to be well suited for experimental studies on denture stomatitis.

Animals↗
PubMed1975

Denture stomatitis. The clinical effects of chlorhexidine and amphotericin B.

The clinical effects of an antibacterial substance with antifungal activity (chlorhexidine) and specific antimycotic (amphotericin B) in denture stomatitis were studied in 100 patients. Five 14-day regimens of chlorhexidine, amphotericin B or placebo lozenges combined with denture immersion in 0.2% chlorhexidine or water were tested. The efficiency of amphotericin B and chlorhexidine was comparable. This indicates that chlorhexidine has a considerable antifungal effect in the oral cavity and, further, that fungi are the responsible micro-organism in denture stomatitis rather than bacteria. Chlorhexidine frequently discloured the dentures. A high incidence of local and general predisposing factors to denture stomatitis, as well as of relapse 14 days after treatment, was observed.

Amphotericin B↗
PubMed1975

Denture stomatitis. Effects of chlorhexidine and amphotericin B on the mycotic flora.

In 100 patients with denture stomatitis cultures and direct smears were used to evaluate 5 treatments, including sucking of chlorhexidine, amphotericin B or placebo tablets combined with denture soaking in 0.2% chlorhexidine or water. After 14 days of treatment the amphotericin B lozenges had brought about a significant reduction in the quantity of fungus on the oral mucosa, whereas they barely affected the large amount present on the fitting surface of the upper denture. Denture immersion in chlorhexidine significantly reduced the number of organisms both on the mucous membrane and on the denture. It therefore seems at least as important to treat the denture as the patient in denture stomatitis. Fourteen days after withdrawal of the drugs the mycotic flora was largely re-established.

Amphotericin B↗
PubMed1978

[Local and systemic antimycotic therapy of Candida-induced denture stomatitis].

15 patients with clinically outstanding prosthesis stomatitis due to microscopically proved candida infection underwent treatment with the antimycotic agent Clotrimazol. After two weeks' therapy improvement was observed in 6 patients (40%), healing in 4 patients (27%); 4 patients did not respond and in one patient the condition was temporally made worse. Examination two weeks after cessation of therapy showed that the clinical condition in 8 patients was as bad as before therapy (53%), and 4 patients (27%) were symptom-free. 3 patients (20%) had improved further. Suggestions for the treatment of prosthesis stomatitis can be derived from these findings.

Bacteriological Techniques↗