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At least 19 recordsLinked to original sources

Normalization of visual fields following bromocriptine treatment in hyperprolactinemic patients with visual field constriction.

Two patients with galactorrhea-amenorrhea and bilateral visual field defects were studied. Routine radiologic examination of each patient revealed a normal sella turcica and no demineralization of the posterior clinoid process. Serum prolactin levels were elevated (patient V. G., 80 ng/ml; patient S. R., 204 ng/ml). Within 2 months of bromocriptine therapy, the serum prolactin levels were normal (patient V. G., 12.21 ng/ml; patient S. R., 8.25 ng/ml) and the bilateral visual field defects were corrected. Bromocriptine has been shown to control prolactin secretion in patients with prolactin-secreting pituitary tumors. Normalization of restricted visual fields following bromocriptine therapy indicates the possibility of an anatomical regression of pituitary hyperplasia or an underlying prolactin-producing microadenoma. It is speculated that the modality of functional galactorrhea reflects hyperplasia of the lactotrophs preceding a nodular and ultimately an adenomatous change. The continuous and prolonged administration of bromocriptine may prevent such a progressive sequence. Further experience is required to validate this possibility.

Adult

Optokinetic eye movements in albino rabbits: inversion in anterior visual field.

When visual contrasts are restricted to the anterior sector (90 degrees to 180 degrees) of the albino rabbit's visual field, eye position is dramatically unstable, and when such contrasts are moved, horizontal optokinetic eye movements are inverted: the direction of pursuit is opposite to that of the stimulus. In the posterior visual field stability and optokinetic reactions are normal, as in all parts of the pigmented rabbit's visual field. This phenomenon may be one more of the complex of visual system defects linked to albinism.

Albinism

Evaluation of the Friedmann Visual Field Analyser.

Visual fields were assessed in 320 eyes of 169 patients, using the Friedmann Visual Field Analyzer (F.V.F.A.) and the Oculus perimeter. The F.V.F.A. was found to be a rapid indicator of both the presence, the location and the density of scotomata. Because some defects were missed by the F.V.F.A. it should be used in combination with some other technique to search for early defects, particularly in the Bjerrum region. Since the F.V.F.A. can be used easily by a technician, the physician's efforts can be utilized to best advantage in exploring those regions likely to contain abnormalities.

Aged

The visual evoked response to word stimuli in the visual fields.

The visual evoked response (VER) has been considered an objective indicator of visual and perceptual processing, although as yet there is no clear evidence of a relationship between visual recognition and electrophysiological activity. The present study was performed to determine whether VER's can provide indications of differences in responses to word stimuli presented in different parts of the visual field. Additionally, evidence was sought as to whether the left and right hemispheres process visual information symmetrically. In 20 adult subjects with normal binocular vision, VER's were recorded simultaneously from left and right hemispheres in response to the repeated presentation of a three-letter word in each of 7 visual field locations. VER's of any subject in response to one stimulus site were consistent and repeatable; intersubject variation was large. For subject comparison, amplitude of VER was the measured response. No significant or consistent amplitude characteristics were identified that related to recognition of the stimulus. From comparison of responses to the different field locations, central stimulation (at 0 degrees) evoked the largest peak-to-trough amplitude (X=8.21 uV+/- 2.56). Amplitudes tended to be larger at 4 degrees than at 2 degrees from center; left field stimulation tended to give larger amplitudes than right field; however, these trends were larger than from the left, this difference was not valid since 11 subjects had larger right hemisphere responses, whereas 9 had larger amplitudes from the left hemisphere. Thus, the study suggests that the VER reflects some net electrical activity from the recording sites that may be traced to an external sensory stimulus and shows that this activity is symmetrical for each hemisphere.

Adult

Static vs dynamic visual field evaluation; with emphasis on the utility of the Friedmann Visual Field Analyzer.

This paper contrasts static and dynamic perimetry, highlighting the advantages and disadvantages of each. A type of static perimetry, the Friedmann Visual Field Analyzer, is discussed in some detail. A clinical study, comparing the sensitivity of the Friedmann Visual Field Analyzer and B&L Autoplot in detecting field defects in known glaucoma patients, is presented. The results of this study support the notion that static fields (utilizing the FVFA) are significantly more sensitive than dynamic fields (utilizing the B&L Autoplot) in detecting field defects in known glaucoma patients.

Diagnostic Errors

Visually evoked cortical potentials in the evaluation of homonymous and bitemporal visual field defects.

Visually evoked cortical potentials were studied in six patients with a homonymous and six with a bitemporal hemianopia by presenting a pattern-reversal stimulus separately to a temporal or nasal retinal area and by recording the responses from leads over the hemispheres. Homonymous visual field defects are characterized by a reduction of VECPs from the affected hemisphere. The disturbance of VECPs in bitemporal hemianopia is more serious, since the fibres from both retinal halves may be damaged by a chiasm tumour.

Evoked Potentials

Disc and field damage in patients with unilateral visual field loss from primary open-angle glaucoma.

To assess the temporal relationship between field and disc change in early glaucoma, 24 patients with unilateral visual field loss from primary open angle glaucoma were identified for planimetric optic disc measurements. Cross-sectional analysis of disc rim area was performed and compared to 25 age-matched normal controls. The mean (+/- SD) disc rim area in eyes with normal visual fields (1.10 +/- 0.31 mm2) was slightly larger than that of eyes with visual field loss (0.90 +/- 0.33 mm2). The mean disc rim area in the control group (1.49 +/- 0.19 mm2) was significantly different from both sets of eyes in the asymmetric primary open angle glaucoma patients (p = 0.000). These findings support the hypothesis that loss of the optic disc rim can be detected before perimetric abnormalities develop in patients with glaucoma.

Aged