[Role of free phenol in the development of encephalopathy in patients with endogenous toxicoses].
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Biomedical subjects
Publications and source records attributed to A I Lobakov.
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Hemofiltration (HF) potentials are presented in complex treatment of 12 patients with disseminated suppurative peritonitis in the phase of polyorgan failure with signs of adult respiratory distress syndrome (ARDS). It has been shown that HF reduces the amount of extravascular fluid in the lungs, increases right-to-left pulmonary shunt, eliminates mediators causing higher permeability of pulmonary vessels, and other medium-molecular toxins. Death was recorded in 6 out of 12 patients. In 3 of the dead patients HF had an obvious positive effect, and death was caused by acute hepatorenal failure. Thus, HF seems promising for the treatment of ARDS in patients with peritonitis.
Central, cerebral, pulmonary and peripheral hemodynamics has been studied using impedance plethysmography in 36 terminally ill patients with pyogenic generalized peritonitis. It has been shown that direct dependence of changes in the cardiac output on its cerebral fraction, as well as impedance findings of brain and lung hydration may be considered as prognostically unfavourable. The onset of hypoperfusion of the vital organs which accompanies peripheral vasodilation and decreased hemodynamic activity is associated with unfavourable vital prognosis.