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Biomedical subjects

B Debesse

Publications and source records attributed to B Debesse.

At least 91 records · Page 5Linked to original sources
PubMed1980

[Sarcoidosis and portal and pulmonary arterial hypertension: a case report (author's transl)].

A 27-year-old patient, originally from Martinique, presented with a progressive hepatic granulomatosis with hepatomegaly, splenomegaly, and non-icteric cholestasis, associated with bronchial granulomatosis lesions. The sarcoidosis regressed rapidly after high doses (60 mg/day) of prednisone. Portal hypertension developed later and provoked a severe hematemesis from rupture of esophageal varices. Signs of pulmonary arterial hypertension were then observed, and the diagnosis confirmed by pressure tests after catheterization, and angiography. A portocaval shunt caused the esophageal varices to subside, but the pulmonary arterial hypertension, resistant to corticotherapy, was rapidly fatal. In the case reported, the pulmonary arterial hypertension, independent of any parenchymatous lesion, was attributed to fibrosis of the arterial walls. The association of portal and pulmonary arterial hypertension with sarcoidosis is a very rare occurrence, and the pathogenesis of this association remains a debatable subject.

Adult↗
PubMed1979

Experimental modifications induced by membrane oxygenators on lung ultrastructure in dogs and baboons.

Extracorporeal circulation with membrane oxygenator (E.C.M.O.) was performed in 6 dogs and 5 baboons during 4 to 57 hours. Examination of pulmonary samples showed progressive lesions in the two species: at the second hour of E.C., alteration of capillary endothelium, at the sixth, extensive lesions of all the lung structures, worsening later on. We discussed whether these lesions are related to the E.C.M.O., their reversibility and the questionable benefit of E.C.M.O. for management of respiratory distress syndrome.

Animals↗
PubMed1976

[Digestive lesions after abdominopelvic irradiation, in the treatment of cancers of the genital tract].

The authors report 15 cases collected over a few years on a gastroenterology unit, and emphasize the digestive complications occurring after pelvic or abdomino-pelvic irradiation for genital carcinoma. The rectum and pelvic colon are generally affected. The delays of onset after radiotherapy may reach or exceed several months. The vascular lesions, caused by ionising radiation, explain the tissue ischemia and, consequently the failure of local medical treatment. When severe hemorrhage or visceral perforation occur, surgery is necessary. However, sutures often break down on these insufficiently vascularised tissues and re-operation is always associated with a poor prognosis.

Aged↗
PubMed1975

[Cystadenocarcinoma of the pancreas. Apropos of 2 cases].

The authors report two cases of cystadenocarcinoma of the pancreas and review the clinical, radiological and angiographic findings. The pathological study may be first disappointing, especially on frozen sections in the operating theater. The diagnosis depends essentially on the finding of an epithelial border which is difficult to demonstrate for it is often interrupted on one part of the circumference. Malignancy is suggested by the characteristics of the cells and the structural disorganisation. Total removal is necessary to avoid relapses, provided one removes neighbouring organs and all invaded lymph nodes. Cystadenomas and cystadeno-carcinomas are very rare tumours. The passage from one to the other seems inevitable. The necessity for surgery is thus absolute. However, if the malignant tumour is irremovable, an anastomosis between the cyst and the digestive tract may temporarily relieve the patient, especially as the course is sometimes rather slow.

Aged↗
PubMed1975

[Operated primary bronchial cancer. Study of the survival of 560 patients].

560 patients with primary broncho-pulmonary carcinoma underwent surgery, excision being possible in 78 p. cent. Overall post-operative survival is 29 p. cent at 5 years and 11.5 p. cent at ten years. Among the various prognostic factors, lymph node involvement is the most important. In the most favourable cases, survival at 5 years is 46 p. cent. Such a result shows that the prognosis in primary carcinoma of the lung is not as grim as it is usually said to be.

Adenocarcinoma↗
PubMed1975

[Re-establishment of tracheal continuity by lowering the larynx after tracheal resection].

The authors describe a technique for re-establishing tracheal continuity after anastomotic resection of the cervical and cervico-thoracic trachea. Simply lowering the larynx cervically without an associated thoracic phase enables termino-terminal anastomosis of the trachea to be carried out after resection of more than 5 cm. In this article, the technique and the results obtained in 8 cases of pure tracheal stenosis are described in detail.

Anesthesia, Intravenous↗